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Journal Abstract Search

111 related items for PubMed ID: 8691988

  • 1. Characterization of the oxidation reactions catalyzed by CYP2D enzyme in rat renal microsomes.
    Masubuchi Y, Yamamoto K, Suzuki T, Horie T, Narimatsu S.
    Life Sci; 1996 May 24; 58(26):2431-7. PubMed ID: 8691988
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  • 2. Selective deficiency of debrisoquine 4-hydroxylase activity in mouse liver microsomes.
    Masubuchi Y, Iwasa T, Hosokawa S, Suzuki T, Horie T, Imaoka S, Funae Y, Narimatsu S.
    J Pharmacol Exp Ther; 1997 Sep 24; 282(3):1435-41. PubMed ID: 9316857
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  • 6. Purification and characterization of a dog cytochrome P450 isozyme belonging to the CYP2D subfamily and development of its antipeptide antibody.
    Nakamura A, Yamamoto Y, Tasaki T, Sugimoto C, Masuda M, Kazusaka A, Fujita S.
    Drug Metab Dispos; 1995 Nov 24; 23(11):1268-73. PubMed ID: 8591729
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  • 7. In vivo administration of H2 blockers, cimetidine and ranitidine, reduced the contents of the cytochrome P450IID (CYP2D) subfamily and their activities in rat liver microsomes.
    Orishiki M, Matsuo Y, Nishioka M, Ichikawa Y.
    Int J Biochem; 1994 Jun 24; 26(6):751-8. PubMed ID: 8063004
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  • 8. Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.
    Masubuchi Y, Igarashi S, Suzuki T, Horie T, Narimatsu S.
    J Pharmacol Exp Ther; 1996 Nov 24; 279(2):724-31. PubMed ID: 8930177
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  • 9. Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase.
    Masubuchi Y, Hosokawa S, Horie T, Suzuki T, Ohmori S, Kitada M, Narimatsu S.
    Drug Metab Dispos; 1994 Nov 24; 22(6):909-15. PubMed ID: 7895609
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  • 10. Polymorphic debrisoquine 4-hydroxylase activity in the rat is due to differences in CYP2D2 expression.
    Schulz-Utermoehl T, Bennett AJ, Ellis SW, Tucker GT, Boobis AR, Edwards RJ.
    Pharmacogenetics; 1999 Jun 24; 9(3):357-66. PubMed ID: 10471068
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  • 11. Inhibition and induction of cytochrome P450 isozymes after repetitive administration of imipramine in rats.
    Masubuchi Y, Takahashii C, Fujio N, Horie T, Suzuki T, Imaoka S, Funae Y, Narimatsu S.
    Drug Metab Dispos; 1995 Sep 24; 23(9):999-1003. PubMed ID: 8565792
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  • 12. Regioselectivity and substrate concentration-dependency of involvement of the CYP2D subfamily in oxidative metabolism of amitriptyline and nortriptyline in rat liver microsomes.
    Masubuchi Y, Iwasa T, Fujita S, Suzuki T, Horie T, Narimatsu S.
    J Pharm Pharmacol; 1996 Sep 24; 48(9):925-9. PubMed ID: 9036183
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  • 13. In-vitro metabolic interaction of bunitrolol enantiomers in rabbit liver microsomes.
    Narimatsu S, Mizukami T, Huang Y, Masubuchi Y, Suzuki T.
    J Pharm Pharmacol; 1996 Nov 24; 48(11):1185-9. PubMed ID: 8961170
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  • 14. Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol.
    Narimatsu S, Arai T, Masubuchi Y, Horie T, Hosokawa M, Ueno K, Kataoka H, Yamamoto S, Ishikawa T, Cho AK.
    Biol Pharm Bull; 2001 Sep 24; 24(9):988-94. PubMed ID: 11558582
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  • 15. In vitro evidence against the oxidation of quinidine by the sparteine/debrisoquine monooxygenase of human liver.
    Otton SV, Brinn RU, Gram LF.
    Drug Metab Dispos; 1988 Sep 24; 16(1):15-7. PubMed ID: 2894945
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  • 16. Molecular basis of the Dark Agouti rat drug oxidation polymorphism: importance of CYP2D1 and CYP2D2.
    Yamamoto Y, Tasaki T, Nakamura A, Iwata H, Kazusaka A, Gonzalez FJ, Fujita S.
    Pharmacogenetics; 1998 Feb 24; 8(1):73-82. PubMed ID: 9511184
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  • 17. Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats.
    Suzuki T, Narimatsu S, Fujita S, Masubuchi Y, Umeda S, Imaoka S, Funae Y.
    Drug Metab Dispos; 1992 Feb 24; 20(3):367-73. PubMed ID: 1355709
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  • 18. The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man.
    Kobayashi S, Murray S, Watson D, Sesardic D, Davies DS, Boobis AR.
    Biochem Pharmacol; 1989 Sep 01; 38(17):2795-9. PubMed ID: 2775304
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  • 19. Development of a high-performance liquid chromatographic method for the analysis of enatiomer/enantiomer interaction in oxidative metabolism of bunitrolol in rat liver microsomes.
    Narimatsu S, Huang Y, Mizukami T, Masubuchi Y, Suzuki T.
    Anal Biochem; 1994 Oct 01; 222(1):256-61. PubMed ID: 7856858
    [Abstract] [Full Text] [Related]

  • 20. Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes.
    Suzuki T, Fujita S, Narimatsu S, Masubuchi Y, Tachibana M, Ohta S, Hirobe M.
    FASEB J; 1992 Jan 06; 6(2):771-6. PubMed ID: 1537468
    [Abstract] [Full Text] [Related]

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