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693 related items for PubMed ID: 8701981

  • 1. Evolution of neoplastic development in the liver of transgenic mice co-expressing c-myc and transforming growth factor-alpha.
    Santoni-Rugiu E, Nagy P, Jensen MR, Factor VM, Thorgeirsson SS.
    Am J Pathol; 1996 Aug; 149(2):407-28. PubMed ID: 8701981
    [Abstract] [Full Text] [Related]

  • 2. Disruption of the pRb/E2F pathway and inhibition of apoptosis are major oncogenic events in liver constitutively expressing c-myc and transforming growth factor alpha.
    Santoni-Rugiu E, Jensen MR, Thorgeirsson SS.
    Cancer Res; 1998 Jan 01; 58(1):123-34. PubMed ID: 9426068
    [Abstract] [Full Text] [Related]

  • 3. Molecular mechanisms of hepatocarcinogenesis in transgenic mouse models of liver cancer.
    Calvisi DF, Thorgeirsson SS.
    Toxicol Pathol; 2005 Jan 01; 33(1):181-4. PubMed ID: 15805070
    [Abstract] [Full Text] [Related]

  • 4. Bcl-2 delays and alters hepatic carcinogenesis induced by transforming growth factor alpha.
    Vail ME, Pierce RH, Fausto N.
    Cancer Res; 2001 Jan 15; 61(2):594-601. PubMed ID: 11212255
    [Abstract] [Full Text] [Related]

  • 5. Activation of beta-catenin during hepatocarcinogenesis in transgenic mouse models: relationship to phenotype and tumor grade.
    Calvisi DF, Factor VM, Loi R, Thorgeirsson SS.
    Cancer Res; 2001 Mar 01; 61(5):2085-91. PubMed ID: 11280770
    [Abstract] [Full Text] [Related]

  • 6. Coexpression of C-myc and transforming growth factor alfa in the liver promotes early replicative senescence and diminishes regenerative capacity after partial hepatectomy in transgenic mice.
    Factor VM, Jensen MR, Thorgeirsson SS.
    Hepatology; 1997 Dec 01; 26(6):1434-43. PubMed ID: 9397983
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  • 10. Differential dependence of the tumorigenicity of chemically transformed rat liver epithelial cells on autocrine production of transforming growth factor alpha.
    Duddy SK, Earp HS, Russell WE, Smith GJ, Grisham JW.
    Cell Growth Differ; 1995 Mar 01; 6(3):251-61. PubMed ID: 7794793
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  • 11. Synergy between truncated c-Met (cyto-Met) and c-Myc in liver oncogenesis: importance of TGF-beta signalling in the control of liver homeostasis and transformation.
    Amicone L, Terradillos O, Calvo L, Costabile B, Cicchini C, Della Rocca C, Lozupone F, Piacentini M, Buendia MA, Tripodi M.
    Oncogene; 2002 Feb 21; 21(9):1335-45. PubMed ID: 11857077
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  • 12. Cooperation of TGF alpha and c-Myc in mouse mammary tumorigenesis: coordinated stimulation of growth and suppression of apoptosis.
    Amundadottir LT, Nass SJ, Berchem GJ, Johnson MD, Dickson RB.
    Oncogene; 1996 Aug 15; 13(4):757-65. PubMed ID: 8761297
    [Abstract] [Full Text] [Related]

  • 13. Ploidy and karyotypic alterations associated with early events in the development of hepatocarcinogenesis in transgenic mice harboring c-myc and transforming growth factor alpha transgenes.
    Sargent LM, Sanderson ND, Thorgeirsson SS.
    Cancer Res; 1996 May 01; 56(9):2137-42. PubMed ID: 8616862
    [Abstract] [Full Text] [Related]

  • 14. Transgenic mouse model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor alpha in hepatic oncogenesis.
    Murakami H, Sanderson ND, Nagy P, Marino PA, Merlino G, Thorgeirsson SS.
    Cancer Res; 1993 Apr 15; 53(8):1719-23. PubMed ID: 8467484
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  • 15. Autonomous growth in serum-free medium and production of hepatocellular carcinomas by differentiated hepatocyte lines that overexpress transforming growth factor alpha 1.
    Wu JC, Merlino G, Cveklova K, Mosinger B, Fausto N.
    Cancer Res; 1994 Nov 15; 54(22):5964-73. PubMed ID: 7525051
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  • 16. Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis.
    Conner EA, Lemmer ER, Omori M, Wirth PJ, Factor VM, Thorgeirsson SS.
    Oncogene; 2000 Oct 19; 19(44):5054-62. PubMed ID: 11042693
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  • 17. Molecular and genetic analysis of liver oncogenesis in transforming growth factor alpha transgenic mice.
    Takagi H, Sharp R, Hammermeister C, Goodrow T, Bradley MO, Fausto N, Merlino G.
    Cancer Res; 1992 Oct 01; 52(19):5171-7. PubMed ID: 1394122
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  • 18. Interactions between MYC and transforming growth factor alpha alter the growth and tumorigenicity of liver progenitor cells.
    Cheung RS, Brooling JT, Johnson MM, Riehle KJ, Campbell JS, Fausto N.
    Carcinogenesis; 2007 Dec 01; 28(12):2624-31. PubMed ID: 17698969
    [Abstract] [Full Text] [Related]

  • 19. Dysregulation of apoptosis by c-myc in transgenic hepatocytes and effects of growth factors and nongenotoxic carcinogens.
    Christensen JG, Goldsworthy TL, Cattley RC.
    Mol Carcinog; 1999 Aug 01; 25(4):273-84. PubMed ID: 10449034
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  • 20. Clonal cosegregation of tumorigenicity with overexpression of c-myc and transforming growth factor alpha genes in chemically transformed rat liver epithelial cells.
    Lee LW, Raymond VW, Tsao MS, Lee DC, Earp HS, Grisham JW.
    Cancer Res; 1991 Oct 01; 51(19):5238-44. PubMed ID: 1717143
    [Abstract] [Full Text] [Related]

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