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Journal Abstract Search


125 related items for PubMed ID: 8702527

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  • 3. A leucine to proline mutation at position 233 in the insulin receptor inhibits cleavage of the proreceptor and transport to the cell surface.
    Maassen JA, Van der Vorm ER, Van der Zon GC, Klinkhamer MP, Krans HM, Möller W.
    Biochemistry; 1991 Nov 05; 30(44):10778-83. PubMed ID: 1931997
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  • 5. Activation of glucose transport by a natural mutation in the human insulin receptor.
    Longo N, Langley SD, Griffin LD, Elsas LJ.
    Proc Natl Acad Sci U S A; 1993 Jan 01; 90(1):60-4. PubMed ID: 8419945
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  • 6. Deletion of V335 from the L2 domain of the insulin receptor results in a conformationally abnormal receptor that is unable to bind insulin and causes Donohue's syndrome in a human subject.
    George S, Johansen A, Soos MA, Mortensen H, Gammeltoft S, Saudek V, Siddle K, Hansen L, O'Rahilly S.
    Endocrinology; 2003 Feb 01; 144(2):631-7. PubMed ID: 12538626
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  • 7. Replacements of leucine 87 in human insulin receptor alter affinity for insulin.
    Nakae J, Morioka H, Ohtsuka E, Fujieda K.
    J Biol Chem; 1995 Sep 15; 270(37):22017-22. PubMed ID: 7665623
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  • 12. Cysteine 981 of the human insulin receptor is required for covalent cross-linking between beta-subunit and a thiol-reactive membrane-associated protein.
    Garant MJ, Maksimova E, Montrose-Rafizadeh C, Lee-Kwon W, Kole S, Bernier M.
    Biochemistry; 2000 Jun 20; 39(24):7178-87. PubMed ID: 10852716
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  • 16. Substitution of arginine for histidine at position 209 in the alpha-subunit of the human insulin receptor. A mutation that impairs receptor dimerization and transport of receptors to the cell surface.
    Kadowaki T, Kadowaki H, Accili D, Yazaki Y, Taylor SI.
    J Biol Chem; 1991 Nov 05; 266(31):21224-31. PubMed ID: 1657953
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  • 17. Characterization of an insulin receptor mutant lacking the subunit processing site.
    Williams JF, McClain DA, Dull TJ, Ullrich A, Olefsky JM.
    J Biol Chem; 1990 May 25; 265(15):8463-9. PubMed ID: 2187866
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  • 18. Effects of amino acid replacements within the tetrabasic cleavage site on the processing of the human insulin receptor precursor expressed in Chinese hamster ovary cells.
    Yoshimasa Y, Paul JI, Whittaker J, Steiner DF.
    J Biol Chem; 1990 Oct 05; 265(28):17230-7. PubMed ID: 2211623
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  • 19. Mutational analysis of the N-linked glycosylation sites of the human insulin receptor.
    Elleman TC, Frenkel MJ, Hoyne PA, McKern NM, Cosgrove L, Hewish DR, Jachno KM, Bentley JD, Sankovich SE, Ward CW.
    Biochem J; 2000 May 01; 347 Pt 3(Pt 3):771-9. PubMed ID: 10769182
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  • 20. Functional properties of a naturally occurring Trp1200----Ser1200 mutation of the insulin receptor.
    Moller DE, Yokota A, Ginsberg-Fellner F, Flier JS.
    Mol Endocrinol; 1990 Aug 01; 4(8):1183-91. PubMed ID: 1963473
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