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152 related items for PubMed ID: 8709168

  • 1. [Single-dose toxicity studies of prulifloxacin (NM441) in mice, rats and dogs and the active metabolite (NM394) in rats].
    Shimazu H, Ishikawa Y, Nishiguchi Y, Yoshida M, Iwakura K, Sumi N, Shindo Y.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():33-44. PubMed ID: 8709168
    [Abstract] [Full Text] [Related]

  • 2. Pharmacokinetics of prulifloxacin. 1st communication: absorption, distribution and excretion in rats, dogs and monkeys after a single administration.
    Okuyama Y, Momota K, Morino A.
    Arzneimittelforschung; 1997 Mar; 47(3):276-84. PubMed ID: 9105546
    [Abstract] [Full Text] [Related]

  • 3. [Renal toxicity of prulifloxacin (NM441) in rats].
    Kawaminami A, Tawaratani T, Ishibashi S, Oka T, Matsuyama S, Kakemi K, Iwakura K, Sumi N, Shindo Y.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():267-76. PubMed ID: 8709167
    [Abstract] [Full Text] [Related]

  • 4. [A 4-week intravenous toxicity study of the active metabolite (NM394) of prulifloxacin (NM441) in rats followed by a 4-week recovery test].
    Ishida S, Iketani M, Yamazaki S, Tamura K, Shindo Y, Iwakura K, Sumi N.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():131-48. PubMed ID: 8709157
    [Abstract] [Full Text] [Related]

  • 5. [Single and 4-week oral toxicity studies of prulifloxacin (NM441) in aged dogs].
    Ihara T, Akune A, Nakama K, Chihaya Y, Nagata R, Sumi N, Asaoka H, Shindo Y.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():149-69. PubMed ID: 8709158
    [Abstract] [Full Text] [Related]

  • 6. Pharmacokinetics of prulifloxacin. 3rd communication: metabolism in rats, dogs and monkeys.
    Okuyama Y, Morino A.
    Arzneimittelforschung; 1997 Mar; 47(3):293-8. PubMed ID: 9105548
    [Abstract] [Full Text] [Related]

  • 7. [A 4-week oral toxicity study of prulifloxacin (NM441) in dogs followed by a 4-week recovery test].
    Oda S, Ide M, Tamura K, Nagatani M, Shindo Y, Iwakura K, Sumi N.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():71-88. PubMed ID: 8709170
    [Abstract] [Full Text] [Related]

  • 8. [A 4-week oral toxicity study of prulifloxacin (NM441) in rats followed by a 4-week recovery test].
    Nishimura N, Fukuda K, Yamazaki S, Tamura K, Shindo Y, Iwakura K, Sumi N.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():45-70. PubMed ID: 8709169
    [Abstract] [Full Text] [Related]

  • 9. [Reproductive and developmental toxicity studies of prulifloxacin (NM441)(2)--A teratogenicity study in rats by oral administration].
    Morinaga T, Fujii S, Furukawa S, Kikumori M, Yasuhira K, Shindo Y, Watanabe M, Sumi N.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():187-206. PubMed ID: 8709161
    [Abstract] [Full Text] [Related]

  • 10. [Antigenicity studies of prulifloxacin (NM441)].
    Tateda C, Sakai K, Yamakawa S, Nakasuji T, Nakamura T, Sumi N, Shindo Y.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():231-9. PubMed ID: 8709164
    [Abstract] [Full Text] [Related]

  • 11. [Mutagenicity studies of prulifloxacin (NM441) and the active metabolite (NM394)].
    Iwakura K, Tamura H, Yamashita Y, Watanabe M, Sumi N, Shindo Y, Ando M, Kojima M.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():241-57. PubMed ID: 8709165
    [Abstract] [Full Text] [Related]

  • 12. [Reproductive and developmental toxicity studies of prulifloxacin (NM441)(4)--A perinatal and postnatal study in rats by oral administration].
    Morinaga T, Fujii S, Okazaki I, Kikumori M, Nishimori T, Shindo Y, Watanabe M, Sumi N.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():219-30. PubMed ID: 8709163
    [Abstract] [Full Text] [Related]

  • 13. [A 13-week oral toxicity study of prulifloxacin (NM441) in dogs followed by a 5-week recovery test].
    Yoshida M, Kawaminami A, Tawaratani T, Uchimoto H, Ishibashi S, Iwakura K, Sumi N, Shindo Y.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():113-29. PubMed ID: 8709156
    [Abstract] [Full Text] [Related]

  • 14. [A 13-week oral toxicity study of prulifloxacin (NM441) in rats followed by a 5-week recovery test].
    Ishibashi S, Nakazawa M, Tawaratani T, Uchimoto H, Yoshida M, Iwakura K, Sumi N, Shindo Y.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():89-111. PubMed ID: 8709171
    [Abstract] [Full Text] [Related]

  • 15. [Reproductive and developmental toxicity studies of prulifloxacin (NM441)(1)--A fertility study in rats by oral administration].
    Morinaga T, Fujii S, Furukawa S, Kikumori M, Yasuhira K, Shindo Y, Watanabe M, Sumi N.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():171-85. PubMed ID: 8709160
    [Abstract] [Full Text] [Related]

  • 16. Pharmacokinetics of prulifloxacin. 2nd communication: pharmacokinetics and effect on hepatic drug-metabolizing enzyme activities after repeated administration and transfer into fetus and milk after a single administration in rats.
    Okuyama Y, Momota K, Morino A.
    Arzneimittelforschung; 1997 Mar; 47(3):285-92. PubMed ID: 9105547
    [Abstract] [Full Text] [Related]

  • 17. Therapeutic effect of the quinolone prodrug prulifloxacin against experimental urinary tract infections in mice.
    Tomii Y, Ozaki M, Matsuda M, Honmura T, Nishimura I, Yamaguchi R, Adachi T, Okawa Y, Nishino T.
    Arzneimittelforschung; 1996 Dec; 46(12):1169-73. PubMed ID: 9006794
    [Abstract] [Full Text] [Related]

  • 18. In vivo antibacterial activity of a prodrug of NM394, a thiazetoquinoline carboxylic acid derivative.
    Ozaki M, Tomii Y, Matsuda M, Segawa J, Kitano M, Kise M, Nishino T.
    Chemotherapy; 1998 Dec; 44(1):21-30. PubMed ID: 9444405
    [Abstract] [Full Text] [Related]

  • 19. [Reproductive and developmental toxicity studies of prulifloxacin (NM441)(3)--A teratogenicity study in rabbits by oral administration].
    Morinaga T, Fujii S, Furukawa S, Kikumori M, Yasuhira K, Shindo Y, Watanabe M, Sumi N.
    J Toxicol Sci; 1996 Jun; 21 Suppl 1():207-17. PubMed ID: 8709162
    [Abstract] [Full Text] [Related]

  • 20. Paraoxonase has a major role in the hydrolysis of prulifloxacin (NM441), a prodrug of a new antibacterial agent.
    Tougou K, Nakamura A, Watanabe S, Okuyama Y, Morino A.
    Drug Metab Dispos; 1998 Apr; 26(4):355-9. PubMed ID: 9531524
    [Abstract] [Full Text] [Related]

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