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Journal Abstract Search

126 related items for PubMed ID: 8714024

  • 1. Progress in the development of oxytocin antagonists for use in preterm labor.
    Pettibone DJ, Guidotti M, Harrell CM, Jasper JR, Lis EV, O'Brien JA, Reiss DR, Woyden CJ, Bock MG, Evans BE.
    Adv Exp Med Biol; 1995; 395():601-12. PubMed ID: 8714024
    [Abstract] [Full Text] [Related]

  • 2. 1-((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo [2.2.1]-heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperaz ine (L-368,899): an orally bioavailable, non-peptide oxytocin antagonist with potential utility for managing preterm labor.
    Williams PD, Anderson PS, Ball RG, Bock MG, Carroll L, Chiu SH, Clineschmidt BV, Culberson JC, Erb JM, Evans BE.
    J Med Chem; 1994 Mar 04; 37(5):565-71. PubMed ID: 8126695
    [Abstract] [Full Text] [Related]

  • 3. Progress in the development of oxytocin antagonists for use in preterm labor.
    Williams PD, Bock MG, Evans BE, Freidinger RM, Pettibone DJ.
    Adv Exp Med Biol; 1998 Mar 04; 449():473-9. PubMed ID: 10026841
    [Abstract] [Full Text] [Related]

  • 4. Potential use of oxytocin and vasopressin V1a antagonists in the treatment of preterm labour and primary dysmenorrhoea.
    Akerlund M, Melin P, Maggi M.
    Adv Exp Med Biol; 1995 Mar 04; 395():595-600. PubMed ID: 8714023
    [Abstract] [Full Text] [Related]

  • 5. 1-(1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4- yl)-4H-3,1-benzoxazin-2(1H)-one (L-371,257): a new, orally bioavailable, non-peptide oxytocin antagonist.
    Williams PD, Clineschmidt BV, Erb JM, Freidinger RM, Guidotti MT, Lis EV, Pawluczyk JM, Pettibone DJ, Reiss DR, Veber DF.
    J Med Chem; 1995 Nov 10; 38(23):4634-6. PubMed ID: 7473590
    [No Abstract] [Full Text] [Related]

  • 6. SSR126768A (4-chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, hydrochloride): a new selective and orally active oxytocin receptor antagonist for the prevention of preterm labor.
    Serradeil-Le Gal C, Valette G, Foulon L, Germain G, Advenier C, Naline E, Bardou M, Martinolle JP, Pouzet B, Raufaste D, Garcia C, Double-Cazanave E, Pauly M, Pascal M, Barbier A, Scatton B, Maffrand JP, Le Fur G.
    J Pharmacol Exp Ther; 2004 Apr 10; 309(1):414-24. PubMed ID: 14722330
    [Abstract] [Full Text] [Related]

  • 7. Identification of an orally active, nonpeptidyl oxytocin antagonist.
    Pettibone DJ, Clineschmidt BV, Kishel MT, Lis EV, Reiss DR, Woyden CJ, Evans BE, Freidinger RM, Veber DF, Cook MJ.
    J Pharmacol Exp Ther; 1993 Jan 10; 264(1):308-14. PubMed ID: 8423533
    [Abstract] [Full Text] [Related]

  • 8. Barusiban suppresses oxytocin-induced preterm labour in non-human primates.
    Reinheimer TM.
    BMC Pregnancy Childbirth; 2007 Jun 01; 7 Suppl 1(Suppl 1):S15. PubMed ID: 17570159
    [Abstract] [Full Text] [Related]

  • 9. Barusiban, a new highly potent and long-acting oxytocin antagonist: pharmacokinetic and pharmacodynamic comparison with atosiban in a cynomolgus monkey model of preterm labor.
    Reinheimer TM, Bee WH, Resendez JC, Meyer JK, Haluska GJ, Chellman GJ.
    J Clin Endocrinol Metab; 2005 Apr 01; 90(4):2275-81. PubMed ID: 15671092
    [Abstract] [Full Text] [Related]

  • 10. Isosteric substitution of Asn5 in antagonists of oxytocin and vasopressin leads to highly selective and potent oxytocin and V1a receptor antagonists: new approaches for the design of potential tocolytics for preterm labor.
    Chan WY, Wo NC, Cheng LL, Manning M.
    J Pharmacol Exp Ther; 1996 May 01; 277(2):999-1003. PubMed ID: 8627583
    [Abstract] [Full Text] [Related]

  • 11. Antagonism of oxytocin in rats and pregnant rhesus monkeys by the novel cyclic hexapeptides, L-366,682 and L-366,948.
    Clineschmidt BV, Pettibone DJ, Reiss DR, Lis EV, Haluska GJ, Novy MJ, Cook MJ, Cukierski MA, Kaufman MJ, Bock MG.
    J Pharmacol Exp Ther; 1991 Mar 01; 256(3):827-32. PubMed ID: 2005582
    [Abstract] [Full Text] [Related]

  • 12. Noncompetitive nature of oxytocin antagonists with general structure Mpa(1)Xxx(2)Sar(7)Arg(8).
    Havass J, Bakos K, Márki A, Gáspár R, Gera L, Stewart JM, Fülöp F, Tóth GK, Zupkó I, Falkay G.
    Peptides; 2002 Aug 01; 23(8):1419-25. PubMed ID: 12182942
    [Abstract] [Full Text] [Related]

  • 13. Design and synthesis of highly selective in vitro and in vivo uterine receptor antagonists of oxytocin: comparisons with Atosiban.
    Manning M, Miteva K, Pancheva S, Stoev S, Wo NC, Chan WY.
    Int J Pept Protein Res; 1995 Aug 01; 46(3-4):244-52. PubMed ID: 8537178
    [Abstract] [Full Text] [Related]

  • 14. Profile of an oxytocin antagonist, RWJ 22164 for treatment of preterm labor in laboratory models of uterine contractility.
    Demarest KT, Hahn DW, Ericson E, Capetola RJ, Fuchs AR, McGuire JL.
    Am J Perinatol; 1989 Apr 01; 6(2):200-4. PubMed ID: 2712917
    [Abstract] [Full Text] [Related]

  • 15. The design of orally bioavailable 2, 5-diketopiperazine oxytocin antagonists: from concept to clinical candidate for premature labor.
    Borthwick AD, Liddle J.
    Med Res Rev; 2011 Jul 01; 31(4):576-604. PubMed ID: 20027670
    [Abstract] [Full Text] [Related]

  • 16. Orally active, nonpeptide oxytocin antagonists.
    Evans BE, Leighton JL, Rittle KE, Gilbert KF, Lundell GF, Gould NP, Hobbs DW, DiPardo RM, Veber DF, Pettibone DJ.
    J Med Chem; 1992 Oct 16; 35(21):3919-27. PubMed ID: 1331449
    [Abstract] [Full Text] [Related]

  • 17. Design of oxytocin antagonists with prolonged action: potential tocolytic agents for the treatment of preterm labor.
    Chan WY, Hruby VJ, Rockway TW, Hlavacek J.
    J Pharmacol Exp Ther; 1986 Oct 16; 239(1):84-7. PubMed ID: 3761199
    [Abstract] [Full Text] [Related]

  • 18. Oxytocin antagonists in preterm labour and delivery.
    Melin P.
    Baillieres Clin Obstet Gynaecol; 1993 Sep 16; 7(3):577-600. PubMed ID: 8252818
    [Abstract] [Full Text] [Related]

  • 19. Effect of an oxytocin antagonist on plasma oxytocin levels during nocturnal uterine contractions in the pregnant baboon.
    An TH, Song CH, Choi BC, Pak SC, Mehendale R, Flouret G.
    Gynecol Endocrinol; 2002 Jun 16; 16(3):173-8. PubMed ID: 12192888
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of spontaneous uterine contractions during the last trimester in pregnant baboons by an oxytocin antagonist.
    Wilson L, Parsons MT, Flouret G.
    Am J Obstet Gynecol; 1990 Dec 16; 163(6 Pt 1):1875-82. PubMed ID: 2256498
    [Abstract] [Full Text] [Related]

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