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Journal Abstract Search

199 related items for PubMed ID: 8756325

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  • 7. Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase.
    Whisstock J, Lesk AM, Carrell R.
    Proteins; 1996 Nov; 26(3):288-303. PubMed ID: 8953650
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  • 8. 6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis.
    Mahadeva R, Dafforn TR, Carrell RW, Lomas DA.
    J Biol Chem; 2002 Mar 01; 277(9):6771-4. PubMed ID: 11773044
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  • 11. Defining the mechanism of polymerization in the serpinopathies.
    Ekeowa UI, Freeke J, Miranda E, Gooptu B, Bush MF, Pérez J, Teckman J, Robinson CV, Lomas DA.
    Proc Natl Acad Sci U S A; 2010 Oct 05; 107(40):17146-51. PubMed ID: 20855577
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  • 12. Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop.
    Wei A, Rubin H, Cooperman BS, Christianson DW.
    Nat Struct Biol; 1994 Apr 05; 1(4):251-8. PubMed ID: 7656054
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  • 13. Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization.
    Krishnan B, Gierasch LM.
    Nat Struct Mol Biol; 2011 Feb 05; 18(2):222-6. PubMed ID: 21258324
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  • 14. Pathogenic alpha 1-antitrypsin polymers are formed by reactive loop-beta-sheet A linkage.
    Sivasothy P, Dafforn TR, Gettins PG, Lomas DA.
    J Biol Chem; 2000 Oct 27; 275(43):33663-8. PubMed ID: 10924508
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  • 17. Alpha 1-antitrypsin Siiyama (Ser53-->Phe). Further evidence for intracellular loop-sheet polymerization.
    Lomas DA, Finch JT, Seyama K, Nukiwa T, Carrell RW.
    J Biol Chem; 1993 Jul 25; 268(21):15333-5. PubMed ID: 8340361
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  • 20. Loop-sheet polymerization: the structural basis of Z alpha 1-antitrypsin accumulation in the liver.
    Lomas DA.
    Clin Sci (Lond); 1994 May 25; 86(5):489-95. PubMed ID: 8033502
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