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Journal Abstract Search

170 related items for PubMed ID: 8761427

  • 1. Effect of tamoxifen feeding on metabolic activation of tamoxifen by the liver of the rhesus monkey: does liver accumulation of inhibitory metabolites protect from tamoxifen-dependent genotoxicity and cancer?
    Comoglio A, Gibbs AH, White IN, Gant T, Martin EA, Smith LL, Gamalero SR, DeMatteis F.
    Carcinogenesis; 1996 Aug; 17(8):1687-93. PubMed ID: 8761427
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  • 2. Species differences in the covalent binding of [14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved.
    White IN, De Matteis F, Gibbs AH, Lim CK, Wolf CR, Henderson C, Smith LL.
    Biochem Pharmacol; 1995 Apr 18; 49(8):1035-42. PubMed ID: 7748182
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  • 3. Characterization of rat cytochrome P450 isozymes involved in the covalent binding of cyclosporin A to microsomal proteins.
    Sadrieh N, Thomas PE.
    Toxicol Appl Pharmacol; 1994 Aug 18; 127(2):222-32. PubMed ID: 8048065
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  • 4. Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.
    Mani C, Pearce R, Parkinson A, Kupfer D.
    Carcinogenesis; 1994 Dec 18; 15(12):2715-20. PubMed ID: 8001226
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  • 6. Examination of microsomal cytochrome P450-catalyzed in vitro activation of o-phenylphenol to DNA binding metabolite(s) by 32P-postlabeling technique.
    Pathak DN, Roy D.
    Carcinogenesis; 1992 Sep 18; 13(9):1593-7. PubMed ID: 1394845
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  • 7. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
    Hissink AM, Oudshoorn MJ, Van Ommen B, Haenen GR, Van Bladeren PJ.
    Chem Res Toxicol; 1996 Dec 18; 9(8):1249-56. PubMed ID: 8951226
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  • 8. In vitro studies on the metabolic activation of the furanopyridine L-754,394, a highly potent and selective mechanism-based inhibitor of cytochrome P450 3A4.
    Sahali-Sahly Y, Balani SK, Lin JH, Baillie TA.
    Chem Res Toxicol; 1996 Sep 18; 9(6):1007-12. PubMed ID: 8870989
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  • 9. Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
    Sadrieh N, Snyderwine EG.
    Carcinogenesis; 1995 Jul 18; 16(7):1549-55. PubMed ID: 7614688
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  • 10. Cytochrome P-450 3A and 2D6 catalyze ortho hydroxylation of 4-hydroxytamoxifen and 3-hydroxytamoxifen (droloxifene) yielding tamoxifen catechol: involvement of catechols in covalent binding to hepatic proteins.
    Dehal SS, Kupfer D.
    Drug Metab Dispos; 1999 Jun 18; 27(6):681-8. PubMed ID: 10348797
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  • 13. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 18; (59):1-66, A1-E7. PubMed ID: 11803702
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  • 15. 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.
    Arlt VM, Hewer A, Sorg BL, Schmeiser HH, Phillips DH, Stiborova M.
    Chem Res Toxicol; 2004 Aug 18; 17(8):1092-101. PubMed ID: 15310241
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  • 16. Species and strain differences in the hepatic cytochrome P450-mediated biotransformation of 1,4-dichlorobenzene.
    Hissink AM, Oudshoorn MJ, Van Ommen B, Van Bladeren PJ.
    Toxicol Appl Pharmacol; 1997 Jul 18; 145(1):1-9. PubMed ID: 9221818
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  • 17. N,N',N''-triethylenethiophosphoramide (thio-TEPA) oxygenation by constitutive hepatic P450 enzymes and modulation of drug metabolism and clearance in vivo by P450-inducing agents.
    Ng SF, Waxman DJ.
    Cancer Res; 1991 May 01; 51(9):2340-5. PubMed ID: 1707751
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