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277 related items for PubMed ID: 8763837
21. Chemosensitivity to the indoloquinone EO9 is correlated with DT-diaphorase activity and its gene expression. Smitskamp-Wilms E, Peters GJ, Pinedo HM, van Ark-Otte J, Giaccone G. Biochem Pharmacol; 1994 Apr 20; 47(8):1325-32. PubMed ID: 7514407 [Abstract] [Full Text] [Related]
23. Establishment of an isogenic human colon tumor model for NQO1 gene expression: application to investigate the role of DT-diaphorase in bioreductive drug activation in vitro and in vivo. Sharp SY, Kelland LR, Valenti MR, Brunton LA, Hobbs S, Workman P. Mol Pharmacol; 2000 Nov 20; 58(5):1146-55. PubMed ID: 11040064 [Abstract] [Full Text] [Related]
28. Factors affecting sensitivity to EO9 in rodent and human tumour cells in vitro: DT-diaphorase activity and hypoxia. Robertson N, Haigh A, Adams GE, Stratford IJ. Eur J Cancer; 1994 Nov 20; 30A(7):1013-9. PubMed ID: 7946565 [Abstract] [Full Text] [Related]
29. DT-diaphorase activity correlates with sensitivity to the indoloquinone EO9 in mouse and human colon carcinomas. Walton MI, Bibby MC, Double JA, Plumb JA, Workman P. Eur J Cancer; 1992 Nov 20; 28A(10):1597-600. PubMed ID: 1389472 [Abstract] [Full Text] [Related]
30. The role of human and rodent DT-diaphorase in the reductive metabolism of hypoxic cell cytotoxins. Walton MI, Sugget N, Workman P. Int J Radiat Oncol Biol Phys; 1992 Nov 20; 22(4):643-7. PubMed ID: 1544831 [Abstract] [Full Text] [Related]
31. Enzyme-directed bioreductive drug development revisited: a commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes, particularly DT-diaphorase. Workman P. Oncol Res; 1994 Nov 20; 6(10-11):461-75. PubMed ID: 7620214 [Abstract] [Full Text] [Related]
33. Structure-activity relationships for DT-diaphorase reduction of hypoxic cell directed agents: indoloquinones and diaziridinyl benzoquinones. Bailey SM, Suggett N, Walton MI, Workman P. Int J Radiat Oncol Biol Phys; 1992 Nov 20; 22(4):649-53. PubMed ID: 1544832 [Abstract] [Full Text] [Related]
34. DT-diaphorase as a target enzyme for biochemical modulation of mitomycin C. Saeki S, Nishiyama M, Toge T. Hiroshima J Med Sci; 1995 Sep 20; 44(3):55-63. PubMed ID: 8567314 [Abstract] [Full Text] [Related]
35. Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice. Loadman PM, Phillips RM, Lim LE, Bibby MC. Biochem Pharmacol; 2000 Apr 01; 59(7):831-7. PubMed ID: 10718341 [Abstract] [Full Text] [Related]
37. Induction of complementary function reductase enzymes in colon cancer cells by dithiole-3-thione versus sodium selenite. Erzinger MM, Bovet C, Uzozie A, Sturla SJ. J Biochem Mol Toxicol; 2015 Jan 01; 29(1):10-20. PubMed ID: 25179160 [Abstract] [Full Text] [Related]
38. Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells. Siegel D, Gibson NW, Preusch PC, Ross D. Cancer Res; 1990 Dec 01; 50(23):7483-9. PubMed ID: 1701346 [Abstract] [Full Text] [Related]