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122 related items for PubMed ID: 8766720

  • 21. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.
    Biochemistry; 1998 Nov 24; 37(47):16465-71. PubMed ID: 9843412
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  • 22. Akt activity in presenilin 1 wild-type and mutation transfected human SH-SY5Y neuroblastoma cells after serum deprivation and high glucose stress.
    Vestling M, Wiehager B, Tanii H, Cowburn RF.
    J Neurosci Res; 2001 Nov 01; 66(3):448-56. PubMed ID: 11746362
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  • 23. Evidence for phosphorylation and oligomeric assembly of presenilin 1.
    Seeger M, Nordstedt C, Petanceska S, Kovacs DM, Gouras GK, Hahne S, Fraser P, Levesque L, Czernik AJ, George-Hyslop PS, Sisodia SS, Thinakaran G, Tanzi RE, Greengard P, Gandy S.
    Proc Natl Acad Sci U S A; 1997 May 13; 94(10):5090-4. PubMed ID: 9144195
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  • 24. The seven-transmembrane spanning topography of the Alzheimer disease-related presenilin proteins in the plasma membranes of cultured cells.
    Dewji NN, Singer SJ.
    Proc Natl Acad Sci U S A; 1997 Dec 09; 94(25):14025-30. PubMed ID: 9391146
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  • 25. The presenilin 1 C92S mutation increases abeta 42 production.
    Lewis PA, Perez-Tur J, Golde TE, Hardy J.
    Biochem Biophys Res Commun; 2000 Oct 14; 277(1):261-3. PubMed ID: 11027672
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  • 26. Developmental expression of wild-type and mutant presenilin-1 in hippocampal neurons from transgenic mice: evidence for novel species-specific properties of human presenilin-1.
    Lévesque L, Annaert W, Craessaerts K, Mathews PM, Seeger M, Nixon RA, Van Leuven F, Gandy S, Westaway D, St George-Hyslop P, De Strooper B, Fraser PE.
    Mol Med; 1999 Aug 14; 5(8):542-54. PubMed ID: 10501657
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  • 30. Amyloidogenic function of the Alzheimer's disease-associated presenilin 1 in the absence of endoproteolysis.
    Steiner H, Romig H, Pesold B, Philipp U, Baader M, Citron M, Loetscher H, Jacobsen H, Haass C.
    Biochemistry; 1999 Nov 02; 38(44):14600-5. PubMed ID: 10545183
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  • 31. Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations.
    Culvenor JG, Ilaya NT, Ryan MT, Canterford L, Hoke DE, Williamson NA, McLean CA, Masters CL, Evin G.
    Eur J Biochem; 2004 Jan 02; 271(2):375-85. PubMed ID: 14717705
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  • 32. Proteasome inhibitors prevent the degradation of familial Alzheimer's disease-linked presenilin 1 and potentiate A beta 42 recovery from human cells.
    Marambaud P, Ancolio K, Lopez-Perez E, Checler F.
    Mol Med; 1998 Mar 02; 4(3):147-57. PubMed ID: 9562973
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  • 36. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.
    Nat Cell Biol; 1999 Dec 02; 1(8):479-85. PubMed ID: 10587643
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  • 37. Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo.
    Thinakaran G, Borchelt DR, Lee MK, Slunt HH, Spitzer L, Kim G, Ratovitsky T, Davenport F, Nordstedt C, Seeger M, Hardy J, Levey AI, Gandy SE, Jenkins NA, Copeland NG, Price DL, Sisodia SS.
    Neuron; 1996 Jul 02; 17(1):181-90. PubMed ID: 8755489
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  • 39. Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C.
    Walter J, Grünberg J, Capell A, Pesold B, Schindzielorz A, Citron M, Mendla K, George-Hyslop PS, Multhaup G, Selkoe DJ, Haass C.
    Proc Natl Acad Sci U S A; 1997 May 13; 94(10):5349-54. PubMed ID: 9144240
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  • 40. Staurosporine-induced activation of caspase-3 is potentiated by presenilin 1 familial Alzheimer's disease mutations in human neuroglioma cells.
    Kovacs DM, Mancini R, Henderson J, Na SJ, Schmidt SD, Kim TW, Tanzi RE.
    J Neurochem; 1999 Dec 13; 73(6):2278-85. PubMed ID: 10582585
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