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152 related items for PubMed ID: 8778348

  • 1. [Mutagenesis of the human histamine H1 receptor and design of new antihistamine agents].
    Differding E, Gillard M, Moguilevsky N, Varsalona F, Noyer M, Daliers J, Goldstein S, Neuwels M, Lassoie MA, Guillaume JP, Bascour M, Bollen A, Hénichart JP.
    J Pharm Belg; 1996; 51(3):155-60. PubMed ID: 8778348
    [Abstract] [Full Text] [Related]

  • 2. Site-directed mutagenesis of the histamine H1 receptor: roles of aspartic acid107, asparagine198 and threonine194.
    Ohta K, Hayashi H, Mizuguchi H, Kagamiyama H, Fujimoto K, Fukui H.
    Biochem Biophys Res Commun; 1994 Sep 15; 203(2):1096-101. PubMed ID: 8093027
    [Abstract] [Full Text] [Related]

  • 3. Delineation of receptor-ligand interactions at the human histamine H1 receptor by a combined approach of site-directed mutagenesis and computational techniques - or - how to bind the H1 receptor.
    Jongejan A, Leurs R.
    Arch Pharm (Weinheim); 2005 Jun 15; 338(5-6):248-59. PubMed ID: 15952243
    [Abstract] [Full Text] [Related]

  • 4. Pharmacological and functional characterisation of the wild-type and site-directed mutants of the human H1 histamine receptor stably expressed in CHO cells.
    Moguilevsky N, Varsalona F, Guillaume JP, Noyer M, Gillard M, Daliers J, Henichart JP, Bollen A.
    J Recept Signal Transduct Res; 1995 Jun 15; 15(1-4):91-102. PubMed ID: 8903934
    [Abstract] [Full Text] [Related]

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  • 7. Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens.
    Bruysters M, Pertz HH, Teunissen A, Bakker RA, Gillard M, Chatelain P, Schunack W, Timmerman H, Leurs R.
    Eur J Pharmacol; 2004 Mar 08; 487(1-3):55-63. PubMed ID: 15033376
    [Abstract] [Full Text] [Related]

  • 8. Homology modelling and binding site mapping of the human histamine H1 receptor.
    Kiss R, Kovári Z, Keseru GM.
    Eur J Med Chem; 2004 Nov 08; 39(11):959-67. PubMed ID: 15501545
    [Abstract] [Full Text] [Related]

  • 9. Pharmacological differences between human and guinea pig histamine H1 receptors: Asn84 (2.61) as key residue within an additional binding pocket in the H1 receptor.
    Bruysters M, Jongejan A, Gillard M, van de Manakker F, Bakker RA, Chatelain P, Leurs R.
    Mol Pharmacol; 2005 Apr 08; 67(4):1045-52. PubMed ID: 15626750
    [Abstract] [Full Text] [Related]

  • 10. Ligand-specific contribution of the N terminus and E2-loop to pharmacological properties of the histamine H1-receptor.
    Strasser A, Wittmann HJ, Seifert R.
    J Pharmacol Exp Ther; 2008 Sep 08; 326(3):783-91. PubMed ID: 18577700
    [Abstract] [Full Text] [Related]

  • 11. N1-(3-cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-yl)propyl]guanidine (UR-AK57), a potent partial agonist for the human histamine H1- and H2-receptors.
    Xie SX, Kraus A, Ghorai P, Ye QZ, Elz S, Buschauer A, Seifert R.
    J Pharmacol Exp Ther; 2006 Jun 08; 317(3):1262-8. PubMed ID: 16554355
    [Abstract] [Full Text] [Related]

  • 12. The noncompetitive antagonism of histamine H1 receptors expressed in Chinese hamster ovary cells by olopatadine hydrochloride: its potency and molecular mechanism.
    Matsumoto Y, Funahashi J, Mori K, Hayashi K, Yano H.
    Pharmacology; 2008 Jun 08; 81(3):266-74. PubMed ID: 18268402
    [Abstract] [Full Text] [Related]

  • 13. Molecular basis for the selective interaction of synthetic agonists with the human histamine H1-receptor compared with the guinea pig H1-receptor.
    Strasser A, Wittmann HJ, Kunze M, Elz S, Seifert R.
    Mol Pharmacol; 2009 Mar 08; 75(3):454-65. PubMed ID: 19047480
    [Abstract] [Full Text] [Related]

  • 14. Unique binding pocket for KW-4679 in the histamine H1 receptor.
    Nonaka H, Otaki S, Ohshima E, Kono M, Kase H, Ohta K, Fukui H, Ichimura M.
    Eur J Pharmacol; 1998 Mar 12; 345(1):111-7. PubMed ID: 9593602
    [Abstract] [Full Text] [Related]

  • 15. Histamine H1-receptor antagonists inhibit nuclear factor-kappaB and activator protein-1 activities via H1-receptor-dependent and -independent mechanisms.
    Roumestan C, Henriquet C, Gougat C, Michel A, Bichon F, Portet K, Jaffuel D, Mathieu M.
    Clin Exp Allergy; 2008 Jun 12; 38(6):947-56. PubMed ID: 18498541
    [Abstract] [Full Text] [Related]

  • 16. Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor.
    Deml KF, Beermann S, Neumann D, Strasser A, Seifert R.
    Mol Pharmacol; 2009 Nov 12; 76(5):1019-30. PubMed ID: 19720730
    [Abstract] [Full Text] [Related]

  • 17. Probing ligand-specific histamine H1- and H2-receptor conformations with NG-acylated Imidazolylpropylguanidines.
    Xie SX, Ghorai P, Ye QZ, Buschauer A, Seifert R.
    J Pharmacol Exp Ther; 2006 Apr 12; 317(1):139-46. PubMed ID: 16394198
    [Abstract] [Full Text] [Related]

  • 18. Three-dimensional models of histamine H3 receptor antagonist complexes and their pharmacophore.
    Axe FU, Bembenek SD, Szalma S.
    J Mol Graph Model; 2006 May 12; 24(6):456-64. PubMed ID: 16386444
    [Abstract] [Full Text] [Related]

  • 19. Analysis of an H1 receptor-mediated, zinc-potentiated vasoconstrictor action of the histidyl dipeptide carnosine in rabbit saphenous vein.
    O'Dowd A, Miller DJ.
    Br J Pharmacol; 1998 Nov 12; 125(6):1272-80. PubMed ID: 9863657
    [Abstract] [Full Text] [Related]

  • 20. Pharmacological profile of histaprodifens at four recombinant histamine H1 receptor species isoforms.
    Strasser A, Striegl B, Wittmann HJ, Seifert R.
    J Pharmacol Exp Ther; 2008 Jan 12; 324(1):60-71. PubMed ID: 17928567
    [Abstract] [Full Text] [Related]

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