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PUBMED FOR HANDHELDS

Journal Abstract Search


105 related items for PubMed ID: 8784450

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  • 2. Development of neural network QSPR models for Hansch substituent constants. 2. Applications in QSAR studies of HIV-1 reverse transcriptase and dihydrofolate reductase inhibitors.
    Chiu TL, So SS.
    J Chem Inf Comput Sci; 2004; 44(1):154-60. PubMed ID: 14741022
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  • 3. QSAR using evolved neural networks for the inhibition of mutant PfDHFR by pyrimethamine derivatives.
    Hecht D, Cheung M, Fogel GB.
    Biosystems; 2008 Apr; 92(1):10-5. PubMed ID: 18160210
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  • 4. Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
    Schormann N, Senkovich O, Walker K, Wright DL, Anderson AC, Rosowsky A, Ananthan S, Shinkre B, Velu S, Chattopadhyay D.
    Proteins; 2008 Dec; 73(4):889-901. PubMed ID: 18536013
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  • 6. Quantitative structure-activity relationships of antimalarial and dihydrofolate reductase inhibition by quinazolines and 5-substituted benzyl-2,4-diaminopyrimidines.
    Hansch C, Fukunaga JY, Jow PY.
    J Med Chem; 1977 Jan; 20(1):96-102. PubMed ID: 319234
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  • 9. Generation of QSAR sets with a self-organizing map.
    Guha R, Serra JR, Jurs PC.
    J Mol Graph Model; 2004 Sep; 23(1):1-14. PubMed ID: 15331049
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  • 14. New 2,4-diamino-5-(2',5'-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity.
    Rosowsky A, Forsch RA, Sibley CH, Inderlied CB, Queener SF.
    J Med Chem; 2004 Mar 11; 47(6):1475-86. PubMed ID: 14998335
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  • 16. Quantitative structure-activity relationships by evolved neural networks for the inhibition of dihydrofolate reductase by pyrimidines.
    Landavazo DG, Fogel GB, Fogel DB.
    Biosystems; 2002 Feb 11; 65(1):37-47. PubMed ID: 11888662
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  • 19. Selective Pneumocystis carinii dihydrofolate reductase inhibitors: design, synthesis, and biological evaluation of new 2,4-diamino-5-substituted-furo[2,3-d]pyrimidines.
    Gangjee A, Guo X, Queener SF, Cody V, Galitsky N, Luft JR, Pangborn W.
    J Med Chem; 1998 Apr 09; 41(8):1263-71. PubMed ID: 9548816
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  • 20. Quantitative structure-activity relationships of 2, 4-diamino-5-(2-X-benzyl)pyrimidines versus bacterial and avian dihydrofolate reductase.
    Selassie CD, Gan WX, Kallander LS, Klein TE.
    J Med Chem; 1998 Oct 22; 41(22):4261-72. PubMed ID: 9784101
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