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Journal Abstract Search

111 related items for PubMed ID: 8786569

  • 1. Theophylline metabolism in human liver microsomes: inhibition studies.
    Tjia JF, Colbert J, Back DJ.
    J Pharmacol Exp Ther; 1996 Mar; 276(3):912-7. PubMed ID: 8786569
    [Abstract] [Full Text] [Related]

  • 2. Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.
    Gallagher EP, Wienkers LC, Stapleton PL, Kunze KL, Eaton DL.
    Cancer Res; 1994 Jan 01; 54(1):101-8. PubMed ID: 8261428
    [Abstract] [Full Text] [Related]

  • 3. Characterization of human liver cytochromes P-450 involved in theophylline metabolism.
    Sarkar MA, Hunt C, Guzelian PS, Karnes HT.
    Drug Metab Dispos; 1992 Jan 01; 20(1):31-7. PubMed ID: 1346993
    [Abstract] [Full Text] [Related]

  • 4. [O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.
    Rodrigues AD, Kukulka MJ, Roberts EM, Ouellet D, Rodgers TR.
    Drug Metab Dispos; 1996 Jan 01; 24(1):126-36. PubMed ID: 8825200
    [Abstract] [Full Text] [Related]

  • 5. Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation.
    Madan A, Parkinson A, Faiman MD.
    Alcohol Clin Exp Res; 1998 Sep 01; 22(6):1212-9. PubMed ID: 9756035
    [Abstract] [Full Text] [Related]

  • 6. [Mechanism of mono-hydroxylation of daidzein in human liver microsomes].
    Peng WX, Li HD, Zhou HH.
    Yao Xue Xue Bao; 2004 Nov 01; 39(11):892-6. PubMed ID: 15696928
    [Abstract] [Full Text] [Related]

  • 7. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ, Yokoyama H, Chiba K, Wanwimolruk S, Ishizaki T.
    J Pharmacol Exp Ther; 1996 Dec 01; 279(3):1327-34. PubMed ID: 8968357
    [Abstract] [Full Text] [Related]

  • 8. Biotransformation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome(s) P-450 in human liver microsomes.
    Campbell ME, Grant DM, Inaba T, Kalow W.
    Drug Metab Dispos; 1987 Dec 01; 15(2):237-49. PubMed ID: 2882985
    [Abstract] [Full Text] [Related]

  • 9. Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism.
    Gates S, Miners JO.
    Br J Clin Pharmacol; 1999 Mar 01; 47(3):299-305. PubMed ID: 10215755
    [Abstract] [Full Text] [Related]

  • 10. Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028.
    Kim H, Yoon YJ, Kim H, Kang S, Cheon HG, Yoo SE, Shin JG, Liu KH.
    Toxicol Lett; 2006 Oct 10; 166(2):105-14. PubMed ID: 16857327
    [Abstract] [Full Text] [Related]

  • 11. Characterization of the NADPH-dependent covalent binding of [14C]halothane to human liver microsomes: a role for cytochrome P4502E1 at low substrate concentrations.
    Madan A, Parkinson A.
    Drug Metab Dispos; 1996 Dec 10; 24(12):1307-13. PubMed ID: 8971135
    [Abstract] [Full Text] [Related]

  • 12. Reappraisal of human CYP isoforms involved in imipramine N-demethylation and 2-hydroxylation: a study using microsomes obtained from putative extensive and poor metabolizers of S-mephenytoin and eleven recombinant human CYPs.
    Koyama E, Chiba K, Tani M, Ishizaki T.
    J Pharmacol Exp Ther; 1997 Jun 10; 281(3):1199-210. PubMed ID: 9190854
    [Abstract] [Full Text] [Related]

  • 13. Metabolism of theophylline by cDNA-expressed human cytochromes P-450.
    Ha HR, Chen J, Freiburghaus AU, Follath F.
    Br J Clin Pharmacol; 1995 Mar 10; 39(3):321-6. PubMed ID: 7619675
    [Abstract] [Full Text] [Related]

  • 14. Identification of the human liver cytochrome P450 enzymes involved in the metabolism of zileuton (ABT-077) and its N-dehydroxylated metabolite, Abbott-66193.
    Machinist JM, Mayer MD, Shet MS, Ferrero JL, Rodrigues AD.
    Drug Metab Dispos; 1995 Oct 10; 23(10):1163-74. PubMed ID: 8654206
    [Abstract] [Full Text] [Related]

  • 15. Oxidative metabolism of the alkaloid rutaecarpine by human cytochrome P450.
    Ueng YF, Don MJ, Jan WC, Wang SY, Ho LK, Chen CF.
    Drug Metab Dispos; 2006 May 10; 34(5):821-7. PubMed ID: 16501007
    [Abstract] [Full Text] [Related]

  • 16. Formation of guanoxabenz from guanabenz in human liver. A new metabolic marker for CYP1A2.
    Clement B, Demesmaeker M.
    Drug Metab Dispos; 1997 Nov 10; 25(11):1266-71. PubMed ID: 9351903
    [Abstract] [Full Text] [Related]

  • 17. Diltiazem inhibition of cytochrome P-450 3A activity is due to metabolite intermediate complex formation.
    Jones DR, Gorski JC, Hamman MA, Mayhew BS, Rider S, Hall SD.
    J Pharmacol Exp Ther; 1999 Sep 10; 290(3):1116-25. PubMed ID: 10454485
    [Abstract] [Full Text] [Related]

  • 18. Theophylline N-demethylations as probes for P4501A1 and P4501A2.
    Sarkar MA, Jackson BJ.
    Drug Metab Dispos; 1994 Sep 10; 22(6):827-34. PubMed ID: 7895598
    [Abstract] [Full Text] [Related]

  • 19. Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1.
    Reid JM, Kuffel MJ, Miller JK, Rios R, Ames MM.
    Clin Cancer Res; 1999 Aug 10; 5(8):2192-7. PubMed ID: 10473105
    [Abstract] [Full Text] [Related]

  • 20. High performance liquid chromatographic determination of theophylline metabolites in human liver microsomes.
    Sarkar MA, Karnes HT.
    Biomed Chromatogr; 1991 Jan 10; 5(1):38-42. PubMed ID: 2032021
    [Abstract] [Full Text] [Related]

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