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Journal Abstract Search

134 related items for PubMed ID: 8786967

  • 1. The use of intracerebral microdialysis for the determination of pharmacokinetic profiles of anticancer drugs in tumor-bearing rat brain.
    de Lange EC, de Vries JD, Zurcher C, Danhof M, de Boer AG, Breimer DD.
    Pharm Res; 1995 Dec; 12(12):1924-31. PubMed ID: 8786967
    [Abstract] [Full Text] [Related]

  • 2. In vivo microdialysis to characterize drug transport in brain tumors: analysis of methotrexate uptake in rat glioma-2 (RG-2)-bearing rats.
    Devineni D, Klein-Szanto A, Gallo JM.
    Cancer Chemother Pharmacol; 1996 Dec; 38(6):499-507. PubMed ID: 8823490
    [Abstract] [Full Text] [Related]

  • 3. Influence of C6 and CNS1 brain tumors on methotrexate pharmacokinetics in plasma and brain tissue.
    Dukic SF, Kaltenbach ML, Heurtaux T, Hoizey G, Lallemand A, Vistelle R.
    J Neurooncol; 2004 Dec; 67(1-2):131-8. PubMed ID: 15072460
    [Abstract] [Full Text] [Related]

  • 4. Pharmacokinetics of methotrexate in the extracellular fluid of brain C6-glioma after intravenous infusion in rats.
    Dukic S, Heurtaux T, Kaltenbach ML, Hoizey G, Lallemand A, Gourdier B, Vistelle R.
    Pharm Res; 1999 Aug; 16(8):1219-25. PubMed ID: 10468023
    [Abstract] [Full Text] [Related]

  • 5. Pharmacokinetics of tumor cell exposure to [14C]methotrexate after intracarotid administration without and with hyperosmotic opening of the blood-brain and blood-tumor barriers in rat brain tumors: a quantitative autoradiographic study.
    Shapiro WR, Voorhies RM, Hiesiger EM, Sher PB, Basler GA, Lipschutz LE.
    Cancer Res; 1988 Feb 01; 48(3):694-701. PubMed ID: 3335031
    [Abstract] [Full Text] [Related]

  • 6. Microdialysis-directed Intra-tumor Pharmacokinetic Modeling of Methotrexate in Mice and Humans.
    Alsulimani HH, Kim J, Sani SN.
    J Pharm Pharm Sci; 2016 Feb 01; 19(2):239-51. PubMed ID: 27518173
    [Abstract] [Full Text] [Related]

  • 7. Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study.
    Blakeley JO, Olson J, Grossman SA, He X, Weingart J, Supko JG, New Approaches to Brain Tumor Therapy (NABTT) Consortium.
    J Neurooncol; 2009 Jan 01; 91(1):51-8. PubMed ID: 18787762
    [Abstract] [Full Text] [Related]

  • 8. Evaluation of methotrexate tissue exposure by in situ microdialysis in a rat model.
    Ekstrøm O, Andersen A, Warren DJ, Giercksky KE, Slørdal L.
    Cancer Chemother Pharmacol; 1994 Jan 01; 34(4):297-301. PubMed ID: 8033296
    [Abstract] [Full Text] [Related]

  • 9. Determination of free extracellular levels of methotrexate by microdialysis in muscle and solid tumor of the rabbit.
    Dukic S, Kaltenbach ML, Gourdier B, Marty H, Vistelle R.
    Pharm Res; 1998 Jan 01; 15(1):133-8. PubMed ID: 9487560
    [Abstract] [Full Text] [Related]

  • 10. CNS penetration of methotrexate and its metabolite 7-hydroxymethotrexate in mice bearing orthotopic Group 3 medulloblastoma tumors and model-based simulations for children.
    Perkins RS, Davis A, Campagne O, Owens TS, Stewart CF.
    Drug Metab Pharmacokinet; 2023 Feb 01; 48():100471. PubMed ID: 36669926
    [Abstract] [Full Text] [Related]

  • 11. Determination of methotrexate and its major metabolite 7-hydroxymethotrexate in mouse plasma and brain tissue by liquid chromatography-tandem mass spectrometry.
    Guo P, Wang X, Liu L, Belinsky MG, Kruh GD, Gallo JM.
    J Pharm Biomed Anal; 2007 Apr 11; 43(5):1789-95. PubMed ID: 17289326
    [Abstract] [Full Text] [Related]

  • 12. Pharmacokinetic profile of methotrexate in psoriatic skin via the oral or subcutaneous route using dermal microdialysis showing higher methotrexate bioavailability in psoriasis plaques than in non-lesional skin.
    Quist SR, Quist J, Birkenmaier J, Stauch T, Gollnick HP.
    J Eur Acad Dermatol Venereol; 2016 Sep 11; 30(9):1537-43. PubMed ID: 27005005
    [Abstract] [Full Text] [Related]

  • 13. Tissue distribution of methotrexate following administration as a solution and as a magnetic microsphere conjugate in rats bearing brain tumors.
    Devineni D, Klein-Szanto A, Gallo JM.
    J Neurooncol; 1995 Sep 11; 24(2):143-52. PubMed ID: 7562001
    [Abstract] [Full Text] [Related]

  • 14. Influence of schedule of administration on methotrexate penetration in brain tumours.
    Dukic SF, Heurtaux T, Kaltenbach ML, Hoizey G, Lallemand A, Vistelle R.
    Eur J Cancer; 2000 Aug 11; 36(12):1578-84. PubMed ID: 10930807
    [Abstract] [Full Text] [Related]

  • 15. Development of a dog microdialysis model for determining synovial fluid pharmacokinetics of anti-arthritis compounds exemplified by methotrexate.
    Qian M, West W, Wu JT, Lu B, Christ DD.
    Pharm Res; 2003 Apr 11; 20(4):605-10. PubMed ID: 12739768
    [Abstract] [Full Text] [Related]

  • 16. Application of in vivo microdialysis to transdermal absorption of methotrexate in rats.
    Matsuyama K, Nakashima M, Nakaboh Y, Ichikawa M, Yano T, Satoh S.
    Pharm Res; 1994 May 11; 11(5):684-6. PubMed ID: 8058637
    [Abstract] [Full Text] [Related]

  • 17. The effects of drug transporter inhibitors on the pharmacokinetics and tissue distribution of methotrexate in normal and tumor-bearing mice: a microdialysis study.
    Sani SN, Henry K, Böhlke M, Kim J, Stricker-Krongrad A, Maher TJ.
    Cancer Chemother Pharmacol; 2010 May 11; 66(1):159-69. PubMed ID: 19816684
    [Abstract] [Full Text] [Related]

  • 18. The Impact of Liposomal Formulations on the Release and Brain Delivery of Methotrexate: An In Vivo Microdialysis Study.
    Hu Y, Rip J, Gaillard PJ, de Lange ECM, Hammarlund-Udenaes M.
    J Pharm Sci; 2017 Sep 11; 106(9):2606-2613. PubMed ID: 28322936
    [Abstract] [Full Text] [Related]

  • 19. Alterations in methotrexate pharmacokinetics by naproxen in the rat as measured by microdialysis.
    Ekstrøm PO, Giercksky KE, Andersen A, Slørdal L.
    Life Sci; 1997 Sep 11; 60(24):PL 359-64. PubMed ID: 9188769
    [Abstract] [Full Text] [Related]

  • 20. Determination of extracellular methotrexate tissue levels by microdialysis in a rat model.
    Ekstrøm PO, Andersen A, Warren DJ, Giercksky KE, Slørdal L.
    Cancer Chemother Pharmacol; 1996 Sep 11; 37(5):394-400. PubMed ID: 8599860
    [Abstract] [Full Text] [Related]

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