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147 related items for PubMed ID: 8796377

  • 1. The effect of a selective 5-lipoxygenase inhibitor, zileuton, on tissue damage in acute colonic inflammation in rats.
    Zarif A, Eiznhamer D, Callaghan C, Doria MI, Broutman L, Keshavarzian A.
    Inflammation; 1996 Jun; 20(3):217-27. PubMed ID: 8796377
    [Abstract] [Full Text] [Related]

  • 2. Effects of zileuton, a new 5-lipoxygenase inhibitor, in experimentally induced colitis in rats.
    Zingarelli B, Squadrito F, Graziani P, Camerini R, Caputi AP.
    Agents Actions; 1993 Jul; 39(3-4):150-6. PubMed ID: 7905704
    [Abstract] [Full Text] [Related]

  • 3. Pre-clinical pharmacology of ICI D2138, a potent orally-active non-redox inhibitor of 5-lipoxygenase.
    McMillan RM, Spruce KE, Crawley GC, Walker ER, Foster SJ.
    Br J Pharmacol; 1992 Dec; 107(4):1042-7. PubMed ID: 1334748
    [Abstract] [Full Text] [Related]

  • 4. Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton.
    Rao NL, Dunford PJ, Xue X, Jiang X, Lundeen KA, Coles F, Riley JP, Williams KN, Grice CA, Edwards JP, Karlsson L, Fourie AM.
    J Pharmacol Exp Ther; 2007 Jun; 321(3):1154-60. PubMed ID: 17371808
    [Abstract] [Full Text] [Related]

  • 5. Intracolonic administration of zileuton, a selective 5-lipoxygenase inhibitor, accelerates healing in a rat model of chronic colitis.
    Bertrán X, Mañé J, Fernández-Bañares F, Castellá E, Bartolí R, Ojanguren I, Esteve M, Gassull MA.
    Gut; 1996 Jun; 38(6):899-904. PubMed ID: 8984030
    [Abstract] [Full Text] [Related]

  • 6. Effects of tepoxalin, a dual inhibitor of cyclooxygenase/5-lipoxygenase, on events associated with NSAID-induced gastrointestinal inflammation.
    Kirchner T, Aparicio B, Argentieri DC, Lau CY, Ritchie DM.
    Prostaglandins Leukot Essent Fatty Acids; 1997 Jun; 56(6):417-23. PubMed ID: 9223651
    [Abstract] [Full Text] [Related]

  • 7. 5-lipoxygenase inhibitory activity of zileuton.
    Carter GW, Young PR, Albert DH, Bouska J, Dyer R, Bell RL, Summers JB, Brooks DW.
    J Pharmacol Exp Ther; 1991 Mar; 256(3):929-37. PubMed ID: 1848634
    [Abstract] [Full Text] [Related]

  • 8. A-78773: a selective, potent 5-lipoxygenase inhibitor.
    Bell RL, Brooks DW, Young PR, Lanni C, Stewart AO, Bouska J, Malo PE, Carter GW.
    J Lipid Mediat; 1993 Mar; 6(1-3):259-64. PubMed ID: 8395248
    [Abstract] [Full Text] [Related]

  • 9. The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation.
    Nickerson-Nutter CL, Medvedeff ED.
    Arthritis Rheum; 1996 Mar; 39(3):515-21. PubMed ID: 8607901
    [Abstract] [Full Text] [Related]

  • 10. Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.
    Pallio G, Bitto A, Pizzino G, Galfo F, Irrera N, Minutoli L, Arcoraci V, Squadrito G, Macrì A, Squadrito F, Altavilla D.
    Eur J Pharmacol; 2016 Oct 15; 789():152-162. PubMed ID: 27450484
    [Abstract] [Full Text] [Related]

  • 11. Colorectal leukotriene B4 synthesis in vitro in inflammatory bowel disease: inhibition by the selective 5-lipoxygenase inhibitor BWA4C.
    Hawthorne AB, Boughton-Smith NK, Whittle BJ, Hawkey CJ.
    Gut; 1992 Apr 15; 33(4):513-7. PubMed ID: 1316305
    [Abstract] [Full Text] [Related]

  • 12. Zileuton reduces inflammatory reaction and brain damage following permanent cerebral ischemia in rats.
    Tu XK, Yang WZ, Wang CH, Shi SS, Zhang YL, Chen CM, Yang YK, Jin CD, Wen S.
    Inflammation; 2010 Oct 15; 33(5):344-52. PubMed ID: 20204486
    [Abstract] [Full Text] [Related]

  • 13. Intrinsic 5-lipoxygenase activity is required for neutrophil responsivity.
    Guidot DM, Repine MJ, Westcott JY, Repine JE.
    Proc Natl Acad Sci U S A; 1994 Aug 16; 91(17):8156-9. PubMed ID: 8058773
    [Abstract] [Full Text] [Related]

  • 14. Phorbol ester-induced dermal inflammation in mice: evaluation of inhibitors of 5-lipoxygenase and antagonists of leukotriene B4 receptor.
    Rao TS, Yu SS, Djuric SW, Isakson PC.
    J Lipid Mediat Cell Signal; 1994 Sep 16; 10(3):213-28. PubMed ID: 7812673
    [Abstract] [Full Text] [Related]

  • 15. Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton.
    Patel NS, Cuzzocrea S, Chatterjee PK, Di Paola R, Sautebin L, Britti D, Thiemermann C.
    Mol Pharmacol; 2004 Aug 16; 66(2):220-7. PubMed ID: 15266012
    [Abstract] [Full Text] [Related]

  • 16. Zileuton alleviates acute cisplatin nephrotoxicity: Inhibition of lipoxygenase pathway favorably modulates the renal oxidative/inflammatory/caspase-3 axis.
    Helmy MM, Hashim AA, Mouneir SM.
    Prostaglandins Other Lipid Mediat; 2018 Mar 16; 135():1-10. PubMed ID: 29355720
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.
    Wallace JL, MacNaughton WK, Morris GP, Beck PL.
    Gastroenterology; 1989 Jan 16; 96(1):29-36. PubMed ID: 2535830
    [Abstract] [Full Text] [Related]

  • 18. A trial of zileuton versus mesalazine or placebo in the maintenance of remission of ulcerative colitis. The European Zileuton Study Group For Ulcerative Colitis.
    Hawkey CJ, Dube LM, Rountree LV, Linnen PJ, Lancaster JF.
    Gastroenterology; 1997 Mar 16; 112(3):718-24. PubMed ID: 9041232
    [Abstract] [Full Text] [Related]

  • 19. Preclinical and clinical activity of zileuton and A-78773.
    Bell RL, Lanni C, Malo PE, Brooks DW, Stewart AO, Hansen R, Rubin P, Carter GW.
    Ann N Y Acad Sci; 1993 Nov 30; 696():205-15. PubMed ID: 8109828
    [Abstract] [Full Text] [Related]

  • 20. ER-34122, a novel dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model.
    Horizoe T, Nagakura N, Chiba K, Shirota H, Shinoda M, Kobayashi N, Numata H, Okamoto Y, Kobayashi S.
    Inflamm Res; 1998 Oct 30; 47(10):375-83. PubMed ID: 9831321
    [Abstract] [Full Text] [Related]

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