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Journal Abstract Search


220 related items for PubMed ID: 8798383

  • 1. Mutation of protease domain residues Lys37-39 in human protein C inhibits activation by the thrombomodulin-thrombin complex without affecting activation by free thrombin.
    Gerlitz B, Grinnell BW.
    J Biol Chem; 1996 Sep 13; 271(37):22285-8. PubMed ID: 8798383
    [Abstract] [Full Text] [Related]

  • 2. Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling.
    Knobe KE, Berntsdotter A, Shen L, Morser J, Dahlbäck B, Villoutreix BO.
    Proteins; 1999 May 01; 35(2):218-34. PubMed ID: 10223294
    [Abstract] [Full Text] [Related]

  • 3. Tryptophans 231 and 234 in protein C report the Ca(2+)-dependent conformational change required for activation by the thrombin-thrombomodulin complex.
    Rezaie AR, Esmon CT.
    Biochemistry; 1995 Sep 26; 34(38):12221-6. PubMed ID: 7547963
    [Abstract] [Full Text] [Related]

  • 4. Mutation of Glu-80-->Lys results in a protein C mutant that no longer requires Ca2+ for rapid activation by the thrombin-thrombomodulin complex.
    Rezaie AR, Mather T, Sussman F, Esmon CT.
    J Biol Chem; 1994 Feb 04; 269(5):3151-4. PubMed ID: 7906267
    [Abstract] [Full Text] [Related]

  • 5. Calcium-dependent activation of protein C by thrombin/thrombomudulin: role of negatively charged amino acids within the activation peptide of protein C.
    Friedrich U, Pötzsch B, Preissner KT, Müller-Berghaus G, Ehrlich H.
    Thromb Haemost; 1994 Oct 04; 72(4):567-72. PubMed ID: 7878634
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  • 7. Identification of a region in protein C involved in thrombomodulin-stimulated activation by thrombin: potential repulsion at anion-binding site I in thrombin.
    Grinnell BW, Gerlitz B, Berg DT.
    Biochem J; 1994 Nov 01; 303 ( Pt 3)(Pt 3):929-33. PubMed ID: 7980464
    [Abstract] [Full Text] [Related]

  • 8. The function of calcium in protein C activation by thrombin and the thrombin-thrombomodulin complex can be distinguished by mutational analysis of protein C derivatives.
    Rezaie AR, Esmon CT.
    J Biol Chem; 1992 Dec 25; 267(36):26104-9. PubMed ID: 1334492
    [Abstract] [Full Text] [Related]

  • 9. Role of Gly197 in the structure and function of protein C.
    Lu Y, Biswas I, Villoutreix BO, Rezaie AR.
    Biochim Biophys Acta Gen Subj; 2021 Jun 25; 1865(6):129892. PubMed ID: 33722640
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  • 11. Occupancy of anion binding exosite 2 on thrombin determines Ca2+ dependence of protein C activation.
    Liu LW, Rezaie AR, Carson CW, Esmon NL, Esmon CT.
    J Biol Chem; 1994 Apr 22; 269(16):11807-12. PubMed ID: 8163479
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  • 13. Characterization of a thrombomodulin binding site on protein C and its comparison to an activated protein C binding site for factor Va.
    Gale AJ, Griffin JH.
    Proteins; 2004 Feb 15; 54(3):433-41. PubMed ID: 14747992
    [Abstract] [Full Text] [Related]

  • 14. Thrombin interacts with thrombomodulin, protein C, and thrombin-activatable fibrinolysis inhibitor via specific and distinct domains.
    Hall SW, Nagashima M, Zhao L, Morser J, Leung LL.
    J Biol Chem; 1999 Sep 03; 274(36):25510-6. PubMed ID: 10464282
    [Abstract] [Full Text] [Related]

  • 15. Glycosaminoglycan contributions to both protein C activation and thrombin inhibition involve a common arginine-rich site in thrombin that includes residues arginine 93, 97, and 101.
    Ye J, Rezaie AR, Esmon CT.
    J Biol Chem; 1994 Jul 08; 269(27):17965-70. PubMed ID: 8027055
    [Abstract] [Full Text] [Related]

  • 16. Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin.
    Koeppe JR, Beach MA, Baerga-Ortiz A, Kerns SJ, Komives EA.
    Biochemistry; 2008 Oct 14; 47(41):10933-9. PubMed ID: 18803401
    [Abstract] [Full Text] [Related]

  • 17. Recombinant human soluble thrombomodulin delivers bounded thrombin to antithrombin III: thrombomodulin associates with free thrombin and is recycled to activate protein c.
    Aritomi M, Watanabe N, Ohishi R, Gomi K, Kiyota T, Yamamoto S, Ishida T, Maruyama I.
    Thromb Haemost; 1993 Sep 01; 70(3):418-22. PubMed ID: 8259541
    [Abstract] [Full Text] [Related]

  • 18. Ser252Asn Mutation Introduces a New N-Linked Glycosylation Site and Causes Type IIb Protein C Deficiency.
    Zhou S, Wu X, Song Y, Li L, Shi C, Lai Z, Ding Q, Wu W, Dai J, Wang X, Lu Y.
    Thromb Haemost; 2024 May 01; 124(5):459-470. PubMed ID: 38011863
    [Abstract] [Full Text] [Related]

  • 19. Mutagenesis studies toward understanding the mechanism of the cofactor function of thrombomodulin.
    Rezaie AR, Yang L.
    Biophys Chem; 2005 Oct 03; 117(3):255-61. PubMed ID: 15970373
    [Abstract] [Full Text] [Related]

  • 20. Glycosylation of human protein C affects its secretion, processing, functional activities, and activation by thrombin.
    Grinnell BW, Walls JD, Gerlitz B.
    J Biol Chem; 1991 May 25; 266(15):9778-85. PubMed ID: 2033065
    [Abstract] [Full Text] [Related]


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