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220 related items for PubMed ID: 8798383
1. Mutation of protease domain residues Lys37-39 in human protein C inhibits activation by the thrombomodulin-thrombin complex without affecting activation by free thrombin. Gerlitz B, Grinnell BW. J Biol Chem; 1996 Sep 13; 271(37):22285-8. PubMed ID: 8798383 [Abstract] [Full Text] [Related]
2. Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling. Knobe KE, Berntsdotter A, Shen L, Morser J, Dahlbäck B, Villoutreix BO. Proteins; 1999 May 01; 35(2):218-34. PubMed ID: 10223294 [Abstract] [Full Text] [Related]
3. Tryptophans 231 and 234 in protein C report the Ca(2+)-dependent conformational change required for activation by the thrombin-thrombomodulin complex. Rezaie AR, Esmon CT. Biochemistry; 1995 Sep 26; 34(38):12221-6. PubMed ID: 7547963 [Abstract] [Full Text] [Related]
4. Mutation of Glu-80-->Lys results in a protein C mutant that no longer requires Ca2+ for rapid activation by the thrombin-thrombomodulin complex. Rezaie AR, Mather T, Sussman F, Esmon CT. J Biol Chem; 1994 Feb 04; 269(5):3151-4. PubMed ID: 7906267 [Abstract] [Full Text] [Related]
5. Calcium-dependent activation of protein C by thrombin/thrombomudulin: role of negatively charged amino acids within the activation peptide of protein C. Friedrich U, Pötzsch B, Preissner KT, Müller-Berghaus G, Ehrlich H. Thromb Haemost; 1994 Oct 04; 72(4):567-72. PubMed ID: 7878634 [Abstract] [Full Text] [Related]
7. Identification of a region in protein C involved in thrombomodulin-stimulated activation by thrombin: potential repulsion at anion-binding site I in thrombin. Grinnell BW, Gerlitz B, Berg DT. Biochem J; 1994 Nov 01; 303 ( Pt 3)(Pt 3):929-33. PubMed ID: 7980464 [Abstract] [Full Text] [Related]
8. The function of calcium in protein C activation by thrombin and the thrombin-thrombomodulin complex can be distinguished by mutational analysis of protein C derivatives. Rezaie AR, Esmon CT. J Biol Chem; 1992 Dec 25; 267(36):26104-9. PubMed ID: 1334492 [Abstract] [Full Text] [Related]
9. Role of Gly197 in the structure and function of protein C. Lu Y, Biswas I, Villoutreix BO, Rezaie AR. Biochim Biophys Acta Gen Subj; 2021 Jun 25; 1865(6):129892. PubMed ID: 33722640 [Abstract] [Full Text] [Related]
13. Characterization of a thrombomodulin binding site on protein C and its comparison to an activated protein C binding site for factor Va. Gale AJ, Griffin JH. Proteins; 2004 Feb 15; 54(3):433-41. PubMed ID: 14747992 [Abstract] [Full Text] [Related]
14. Thrombin interacts with thrombomodulin, protein C, and thrombin-activatable fibrinolysis inhibitor via specific and distinct domains. Hall SW, Nagashima M, Zhao L, Morser J, Leung LL. J Biol Chem; 1999 Sep 03; 274(36):25510-6. PubMed ID: 10464282 [Abstract] [Full Text] [Related]
15. Glycosaminoglycan contributions to both protein C activation and thrombin inhibition involve a common arginine-rich site in thrombin that includes residues arginine 93, 97, and 101. Ye J, Rezaie AR, Esmon CT. J Biol Chem; 1994 Jul 08; 269(27):17965-70. PubMed ID: 8027055 [Abstract] [Full Text] [Related]
16. Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin. Koeppe JR, Beach MA, Baerga-Ortiz A, Kerns SJ, Komives EA. Biochemistry; 2008 Oct 14; 47(41):10933-9. PubMed ID: 18803401 [Abstract] [Full Text] [Related]
17. Recombinant human soluble thrombomodulin delivers bounded thrombin to antithrombin III: thrombomodulin associates with free thrombin and is recycled to activate protein c. Aritomi M, Watanabe N, Ohishi R, Gomi K, Kiyota T, Yamamoto S, Ishida T, Maruyama I. Thromb Haemost; 1993 Sep 01; 70(3):418-22. PubMed ID: 8259541 [Abstract] [Full Text] [Related]
18. Ser252Asn Mutation Introduces a New N-Linked Glycosylation Site and Causes Type IIb Protein C Deficiency. Zhou S, Wu X, Song Y, Li L, Shi C, Lai Z, Ding Q, Wu W, Dai J, Wang X, Lu Y. Thromb Haemost; 2024 May 01; 124(5):459-470. PubMed ID: 38011863 [Abstract] [Full Text] [Related]
19. Mutagenesis studies toward understanding the mechanism of the cofactor function of thrombomodulin. Rezaie AR, Yang L. Biophys Chem; 2005 Oct 03; 117(3):255-61. PubMed ID: 15970373 [Abstract] [Full Text] [Related]
20. Glycosylation of human protein C affects its secretion, processing, functional activities, and activation by thrombin. Grinnell BW, Walls JD, Gerlitz B. J Biol Chem; 1991 May 25; 266(15):9778-85. PubMed ID: 2033065 [Abstract] [Full Text] [Related] Page: [Next] [New Search]