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Journal Abstract Search

873 related items for PubMed ID: 8801053

  • 1. Metabolism of 2-amino-alpha-carboline. A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2.
    Raza H, King RS, Squires RB, Guengerich FP, Miller DW, Freeman JP, Lang NP, Kadlubar FF.
    Drug Metab Dispos; 1996 Apr; 24(4):395-400. PubMed ID: 8801053
    [Abstract] [Full Text] [Related]

  • 2. Human cytochromes P4501A1 and P4501A2: R-warfarin metabolism as a probe.
    Zhang Z, Fasco MJ, Huang Z, Guengerich FP, Kaminsky LS.
    Drug Metab Dispos; 1995 Dec; 23(12):1339-46. PubMed ID: 8689941
    [Abstract] [Full Text] [Related]

  • 3. Cytochrome P4501A1 mediates the metabolism of 2,3,7,8-tetrachlorodibenzofuran in the rat and human.
    Tai HL, McReynolds JH, Goldstein JA, Eugster HP, Sengstag C, Alworth WL, Olson JR.
    Toxicol Appl Pharmacol; 1993 Nov; 123(1):34-42. PubMed ID: 8236259
    [Abstract] [Full Text] [Related]

  • 4. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [Abstract] [Full Text] [Related]

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  • 6. Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.
    Shimada T, Yamazaki H, Mimura M, Wakamiya N, Ueng YF, Guengerich FP, Inui Y.
    Drug Metab Dispos; 1996 May; 24(5):515-22. PubMed ID: 8723730
    [Abstract] [Full Text] [Related]

  • 7. Rat liver cytochrome P450 metabolism of N-acetylbenzidine and N,N'-diacetylbenzidine.
    Lakshmi VM, Zenser TV, Davis BB.
    Drug Metab Dispos; 1997 Apr; 25(4):481-8. PubMed ID: 9107548
    [Abstract] [Full Text] [Related]

  • 8. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
    Turesky RJ, Constable A, Richoz J, Varga N, Markovic J, Martin MV, Guengerich FP.
    Chem Res Toxicol; 1998 Aug; 11(8):925-36. PubMed ID: 9705755
    [Abstract] [Full Text] [Related]

  • 9. Two food-borne heterocyclic amines: metabolism and DNA adduct formation of amino-alpha-carbolines.
    Frederiksen H.
    Mol Nutr Food Res; 2005 Mar; 49(3):263-73. PubMed ID: 15704238
    [Abstract] [Full Text] [Related]

  • 10. Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450.
    Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E, Stiborová M.
    Chem Res Toxicol; 2004 May; 17(5):663-71. PubMed ID: 15144223
    [Abstract] [Full Text] [Related]

  • 11. Metabolic oxidation of the carcinogens 4-aminobiphenyl and 4,4'-methylene-bis(2-chloroaniline) by human hepatic microsomes and by purified rat hepatic cytochrome P-450 monooxygenases.
    Butler MA, Guengerich FP, Kadlubar FF.
    Cancer Res; 1989 Jan 01; 49(1):25-31. PubMed ID: 2908851
    [Abstract] [Full Text] [Related]

  • 12. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
    Yao HT, Wu YS, Chang YW, Hsieh HP, Chen WC, Lan SJ, Chen CT, Chao YS, Chang L, Sun HY, Yeh TK.
    Drug Metab Dispos; 2007 Jul 01; 35(7):1042-9. PubMed ID: 17403915
    [Abstract] [Full Text] [Related]

  • 13. Theophylline N-demethylations as probes for P4501A1 and P4501A2.
    Sarkar MA, Jackson BJ.
    Drug Metab Dispos; 1994 Jul 01; 22(6):827-34. PubMed ID: 7895598
    [Abstract] [Full Text] [Related]

  • 14. Characterization of the oxidation of amine metabolites of nitrotoluenes by rat hepatic microsomes. N- and C-hydroxylation.
    Kedderis GL, Rickert DE.
    Mol Pharmacol; 1985 Aug 01; 28(2):207-14. PubMed ID: 4022002
    [Abstract] [Full Text] [Related]

  • 15. Androgen-dependent renal microsomal cytochrome P-450 responsible for N-hydroxylation and mutagenic activation of 3-methoxy-4-aminoazobenzene in the BALB/c mouse.
    Degawa M, Miura S, Hashimoto Y.
    Cancer Res; 1990 May 01; 50(9):2729-33. PubMed ID: 2328499
    [Abstract] [Full Text] [Related]

  • 16. Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes.
    Shimada T, Guengerich FP.
    Cancer Res; 1991 Oct 01; 51(19):5284-91. PubMed ID: 1913651
    [Abstract] [Full Text] [Related]

  • 17. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T, Shiraga T, Mitani Y, Terakawa M, Tokuma Y, Kagayama A.
    Drug Metab Dispos; 2000 Sep 01; 28(9):1128-34. PubMed ID: 10950860
    [Abstract] [Full Text] [Related]

  • 18. In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline.
    King RS, Teitel CH, Kadlubar FF.
    Carcinogenesis; 2000 Jul 01; 21(7):1347-54. PubMed ID: 10874013
    [Abstract] [Full Text] [Related]

  • 19. Species differences in the toxicity and cytochrome P450 IIIA-dependent metabolism of digitoxin.
    Eberhart DC, Gemzik B, Halvorson MR, Parkinson A.
    Mol Pharmacol; 1991 Nov 01; 40(5):859-67. PubMed ID: 1944247
    [Abstract] [Full Text] [Related]

  • 20. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2001 Feb 01; 29(2):200-5. PubMed ID: 11159812
    [Abstract] [Full Text] [Related]

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