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330 related items for PubMed ID: 8810295

  • 1. Phosphatidylinositol 4,5-bisphosphate binding to the pleckstrin homology domain of phospholipase C-delta1 enhances enzyme activity.
    Lomasney JW, Cheng HF, Wang LP, Kuan Y, Liu S, Fesik SW, King K.
    J Biol Chem; 1996 Oct 11; 271(41):25316-26. PubMed ID: 8810295
    [Abstract] [Full Text] [Related]

  • 2. Positive charge at position 549 is essential for phosphatidylinositol 4,5-bisphosphate-hydrolyzing but not phosphatidylinositol-hydrolyzing activities of human phospholipase C delta1.
    Wang LP, Lim C, Kuan Y, Chen CL, Chen HF, King K.
    J Biol Chem; 1996 Oct 04; 271(40):24505-16. PubMed ID: 8798711
    [Abstract] [Full Text] [Related]

  • 3. A single amino acid substitution in the pleckstrin homology domain of phospholipase C delta1 enhances the rate of substrate hydrolysis.
    Bromann PA, Boetticher EE, Lomasney JW.
    J Biol Chem; 1997 Jun 27; 272(26):16240-6. PubMed ID: 9195925
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  • 4. Activation of phospholipase C delta1 through C2 domain by a Ca(2+)-enzyme-phosphatidylserine ternary complex.
    Lomasney JW, Cheng HF, Roffler SR, King K.
    J Biol Chem; 1999 Jul 30; 274(31):21995-2001. PubMed ID: 10419523
    [Abstract] [Full Text] [Related]

  • 5. Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis.
    Cheng HF, Jiang MJ, Chen CL, Liu SM, Wong LP, Lomasney JW, King K.
    J Biol Chem; 1995 Mar 10; 270(10):5495-505. PubMed ID: 7890667
    [Abstract] [Full Text] [Related]

  • 6. Replacements of single basic amino acids in the pleckstrin homology domain of phospholipase C-delta1 alter the ligand binding, phospholipase activity, and interaction with the plasma membrane.
    Yagisawa H, Sakuma K, Paterson HF, Cheung R, Allen V, Hirata H, Watanabe Y, Hirata M, Williams RL, Katan M.
    J Biol Chem; 1998 Jan 02; 273(1):417-24. PubMed ID: 9417098
    [Abstract] [Full Text] [Related]

  • 7. Catalytic domain of phosphoinositide-specific phospholipase C (PLC). Mutational analysis of residues within the active site and hydrophobic ridge of plcdelta1.
    Ellis MV, James SR, Perisic O, Downes CP, Williams RL, Katan M.
    J Biol Chem; 1998 May 08; 273(19):11650-9. PubMed ID: 9565585
    [Abstract] [Full Text] [Related]

  • 8. Group IV cytosolic phospholipase A2 binds with high affinity and specificity to phosphatidylinositol 4,5-bisphosphate resulting in dramatic increases in activity.
    Mosior M, Six DA, Dennis EA.
    J Biol Chem; 1998 Jan 23; 273(4):2184-91. PubMed ID: 9442060
    [Abstract] [Full Text] [Related]

  • 9. Catalysis by phospholipase C delta1 requires that Ca2+ bind to the catalytic domain, but not the C2 domain.
    Grobler JA, Hurley JH.
    Biochemistry; 1998 Apr 07; 37(14):5020-8. PubMed ID: 9538021
    [Abstract] [Full Text] [Related]

  • 10. The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes.
    Garcia P, Gupta R, Shah S, Morris AJ, Rudge SA, Scarlata S, Petrova V, McLaughlin S, Rebecchi MJ.
    Biochemistry; 1995 Dec 12; 34(49):16228-34. PubMed ID: 8519781
    [Abstract] [Full Text] [Related]

  • 11. Involvement of EF hand motifs in the Ca(2+)-dependent binding of the pleckstrin homology domain to phosphoinositides.
    Yamamoto T, Takeuchi H, Kanematsu T, Allen V, Yagisawa H, Kikkawa U, Watanabe Y, Nakasima A, Katan M, Hirata M.
    Eur J Biochem; 1999 Oct 01; 265(1):481-90. PubMed ID: 10491207
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  • 15. The pleckstrin homology domain of phosphoinositide-specific phospholipase Cdelta4 is not a critical determinant of the membrane localization of the enzyme.
    Lee SB, Várnai P, Balla A, Jalink K, Rhee SG, Balla T.
    J Biol Chem; 2004 Jun 04; 279(23):24362-71. PubMed ID: 15037625
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  • 16. Phosphatidylserine induces functional and structural alterations of the membrane-associated pleckstrin homology domain of phospholipase C-delta1.
    Uekama N, Sugita T, Okada M, Yagisawa H, Tuzi S.
    FEBS J; 2007 Jan 04; 274(1):177-87. PubMed ID: 17222180
    [Abstract] [Full Text] [Related]

  • 17. Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid.
    Pitcher JA, Touhara K, Payne ES, Lefkowitz RJ.
    J Biol Chem; 1995 May 19; 270(20):11707-10. PubMed ID: 7744811
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  • 19. The Pleckstrin homology domains of phospholipases C-beta and -delta confer activation through a common site.
    Guo Y, Philip F, Scarlata S.
    J Biol Chem; 2003 Aug 08; 278(32):29995-30004. PubMed ID: 12761218
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  • 20. The pleckstrin homology domain of phospholipase Cbeta transmits enzymatic activation through modulation of the membrane-domain orientation.
    Drin G, Douguet D, Scarlata S.
    Biochemistry; 2006 May 09; 45(18):5712-24. PubMed ID: 16669615
    [Abstract] [Full Text] [Related]

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