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Journal Abstract Search

195 related items for PubMed ID: 8810309

  • 21. Probing the substrate alignment at the active site of 15-lipoxygenases by targeted substrate modification and site-directed mutagenesis. Evidence for an inverse substrate orientation.
    Schwarz K, Borngräber S, Anton M, Kuhn H.
    Biochemistry; 1998 Nov 03; 37(44):15327-35. PubMed ID: 9799493
    [Abstract] [Full Text] [Related]

  • 22. Kinetic investigations of the rate-limiting step in human 12- and 15-lipoxygenase.
    Segraves EN, Holman TR.
    Biochemistry; 2003 May 13; 42(18):5236-43. PubMed ID: 12731864
    [Abstract] [Full Text] [Related]

  • 23. A single active site residue directs oxygenation stereospecificity in lipoxygenases: stereocontrol is linked to the position of oxygenation.
    Coffa G, Brash AR.
    Proc Natl Acad Sci U S A; 2004 Nov 02; 101(44):15579-84. PubMed ID: 15496467
    [Abstract] [Full Text] [Related]

  • 24. Role of Arg403 for thermostability and catalytic activity of rabbit 12/15-lipoxygenase.
    Di Venere A, Horn T, Stehling S, Mei G, Masgrau L, González-Lafont A, Kühn H, Ivanov I.
    Biochim Biophys Acta; 2013 Jun 02; 1831(6):1079-88. PubMed ID: 23438511
    [Abstract] [Full Text] [Related]

  • 25. Is ATP a substrate for 15-lipoxygenase?
    Kumarathasan R, Leenen FH.
    Biochem Cell Biol; 2000 Jun 02; 78(2):87-91. PubMed ID: 10874469
    [Abstract] [Full Text] [Related]

  • 26. Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities.
    Kakularam KR, Canyelles-Niño M, Chen X, Lluch JM, González-Lafont À, Kuhn H.
    Int J Mol Sci; 2023 Jun 12; 24(12):. PubMed ID: 37373195
    [Abstract] [Full Text] [Related]

  • 27. Identification of the iron-binding histidine residues in soybean lipoxygenase L-1.
    Steczko J, Axelrod B.
    Biochem Biophys Res Commun; 1992 Jul 31; 186(2):686-9. PubMed ID: 1497657
    [Abstract] [Full Text] [Related]

  • 28. The N-terminal domain of the reticulocyte-type 15-lipoxygenase is not essential for enzymatic activity but contains determinants for membrane binding.
    Walther M, Anton M, Wiedmann M, Fletterick R, Kuhn H.
    J Biol Chem; 2002 Jul 26; 277(30):27360-6. PubMed ID: 12004065
    [Abstract] [Full Text] [Related]

  • 29. Arachidonate 12-lipoxygenases with reference to their selective inhibitors.
    Yamamoto S, Katsukawa M, Nakano A, Hiraki E, Nishimura K, Jisaka M, Yokota K, Ueda N.
    Biochem Biophys Res Commun; 2005 Dec 09; 338(1):122-7. PubMed ID: 16171776
    [Abstract] [Full Text] [Related]

  • 30. Omega-oxidation impairs oxidizability of polyenoic fatty acids by 15-lipoxygenases: consequences for substrate orientation at the active site.
    Ivanov I, Schwarz K, Holzhütter HG, Myagkova G, Kühn H.
    Biochem J; 1998 Dec 01; 336 ( Pt 2)(Pt 2):345-52. PubMed ID: 9820810
    [Abstract] [Full Text] [Related]

  • 31. Affinities of various mammalian arachidonate lipoxygenases and cyclooxygenases for molecular oxygen as substrate.
    Juránek I, Suzuki H, Yamamoto S.
    Biochim Biophys Acta; 1999 Jan 04; 1436(3):509-18. PubMed ID: 9989280
    [Abstract] [Full Text] [Related]

  • 32. Creating lipoxygenases with new positional specificities by site-directed mutagenesis.
    Hornung E, Rosahl S, Kühn H, Feussner I.
    Biochem Soc Trans; 2000 Dec 04; 28(6):825-6. PubMed ID: 11171221
    [Abstract] [Full Text] [Related]

  • 33. The three-dimensional structure of soybean lipoxygenase-1: an arachidonic acid 15-lipoxygenase.
    Boyington JC, Gaffney BJ, Amzel LM.
    Adv Exp Med Biol; 1997 Dec 04; 400A():133-8. PubMed ID: 9547548
    [No Abstract] [Full Text] [Related]

  • 34. Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase.
    Aleem AM, Tsai WC, Tena J, Alvarez G, Deschamps J, Kalyanaraman C, Jacobson MP, Holman T.
    Biochemistry; 2019 Feb 12; 58(6):848-857. PubMed ID: 30565457
    [Abstract] [Full Text] [Related]

  • 35. Conditions for the formation of the oxo derivatives of arachidonic acid from platelet 12-lipoxygenase and soybean 15-lipoxygenase.
    Fruteau de Laclos B, Borgeat P.
    Biochim Biophys Acta; 1988 Feb 19; 958(3):424-33. PubMed ID: 3124882
    [Abstract] [Full Text] [Related]

  • 36. Cloning, purification and characterization of non-human primate 12/15-lipoxygenases.
    Johannesson M, Backman L, Claesson HE, Forsell PK.
    Prostaglandins Leukot Essent Fatty Acids; 2010 Feb 19; 82(2-3):121-9. PubMed ID: 20106647
    [Abstract] [Full Text] [Related]

  • 37. Site-directed mutagenesis studies on the iron-binding domain and the determinant for the substrate oxygenation site of porcine leukocyte arachidonate 12-lipoxygenase.
    Suzuki H, Kishimoto K, Yoshimoto T, Yamamoto S, Kanai F, Ebina Y, Miyatake A, Tanabe T.
    Biochim Biophys Acta; 1994 Jan 20; 1210(3):308-16. PubMed ID: 8305485
    [Abstract] [Full Text] [Related]

  • 38. Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies.
    Palmieri-Thiers C, Alberti JC, Canaan S, Brunini V, Gambotti C, Tomi F, Oliw EH, Berti L, Maury J.
    Arch Biochem Biophys; 2011 May 01; 509(1):82-9. PubMed ID: 21345329
    [Abstract] [Full Text] [Related]

  • 39. Molecular-dynamics simulation of dioxygen egress from 12/15-lipoxygenase-arachidonic acid complex.
    Pietra F.
    Chem Biodivers; 2012 Jun 01; 9(6):1019-32. PubMed ID: 22700222
    [Abstract] [Full Text] [Related]

  • 40. cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases.
    Chen XS, Kurre U, Jenkins NA, Copeland NG, Funk CD.
    J Biol Chem; 1994 May 13; 269(19):13979-87. PubMed ID: 8188678
    [Abstract] [Full Text] [Related]

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