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Journal Abstract Search


120 related items for PubMed ID: 8820429

  • 1. Short-term maintenance of phase I and II metabolism in precision-cut liver slices in dynamic organ culture.
    Ekins S.
    Drug Metab Dispos; 1996 Mar; 24(3):364-6. PubMed ID: 8820429
    [Abstract] [Full Text] [Related]

  • 2. Xenobiotic metabolism in rat, dog, and human precision-cut liver slices, freshly isolated hepatocytes, and vitrified precision-cut liver slices.
    Ekins S, Williams JA, Murray GI, Burke MD, Marchant NC, Engeset J, Hawksworth GM.
    Drug Metab Dispos; 1996 Sep; 24(9):990-5. PubMed ID: 8886609
    [Abstract] [Full Text] [Related]

  • 3. Quantitative differences in phase I and II metabolism between rat precision-cut liver slices and isolated hepatocytes.
    Ekins S, Murray GI, Burke MD, Williams JA, Marchant NC, Hawksworth GM.
    Drug Metab Dispos; 1995 Nov; 23(11):1274-9. PubMed ID: 8591730
    [Abstract] [Full Text] [Related]

  • 4. Metabolism of coumarin and 7-ethoxycoumarin by rat, mouse, guinea pig, cynomolgus monkey and human precision-cut liver slices.
    Steensma A, Beamand JA, Walters DG, Price RJ, Lake BG.
    Xenobiotica; 1994 Sep; 24(9):893-907. PubMed ID: 7810171
    [Abstract] [Full Text] [Related]

  • 5. Alterations of the catalytic activities of drug-metabolizing enzymes in cultures of human liver slices.
    VandenBranden M, Wrighton SA, Ekins S, Gillespie JS, Binkley SN, Ring BJ, Gadberry MG, Mullins DC, Strom SC, Jensen CB.
    Drug Metab Dispos; 1998 Nov; 26(11):1063-8. PubMed ID: 9806947
    [Abstract] [Full Text] [Related]

  • 6. Stability of cytochromes P450 and phase II conjugation systems in precision-cut rat lung slices cultured up to 72 h.
    Umachandran M, Ioannides C.
    Toxicology; 2006 Jul 05; 224(1-2):14-21. PubMed ID: 16701934
    [Abstract] [Full Text] [Related]

  • 7. [14C]7-ethoxycoumarin metabolism by precision-cut rat hepatic slices.
    Ball SE, Thiel VE, Tio CO, Lim HK, Kao J, Sisenwine SF, Scatina J.
    Drug Metab Dispos; 1996 Apr 05; 24(4):383-9. PubMed ID: 8801051
    [Abstract] [Full Text] [Related]

  • 8. Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity.
    Carlile DJ, Hakooz N, Houston JB.
    Drug Metab Dispos; 1999 Apr 05; 27(4):526-32. PubMed ID: 10101148
    [Abstract] [Full Text] [Related]

  • 9. Empirical validation of a rat in vitro organ slice model as a tool for in vivo clearance prediction.
    de Graaf IA, de Kanter R, de Jager MH, Camacho R, Langenkamp E, van de Kerkhof EG, Groothuis GM.
    Drug Metab Dispos; 2006 Apr 05; 34(4):591-9. PubMed ID: 16415126
    [Abstract] [Full Text] [Related]

  • 10. Differential maintenance of cytochrome P450 enzymes in cultured precision-cut human liver slices.
    Renwick AB, Watts PS, Edwards RJ, Barton PT, Guyonnet I, Price RJ, Tredger JM, Pelkonen O, Boobis AR, Lake BG.
    Drug Metab Dispos; 2000 Oct 05; 28(10):1202-9. PubMed ID: 10997941
    [Abstract] [Full Text] [Related]

  • 11. Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium.
    Catania JR, McGarrigle BP, Rittenhouse-Olson K, Olson JR.
    Toxicol In Vitro; 2007 Feb 05; 21(1):109-15. PubMed ID: 17011741
    [Abstract] [Full Text] [Related]

  • 12. [Application of precision-cut liver slice to the study of the effect of glutathione on cadmium chloride hepatotoxicity].
    Yang Z, Peng R, Xi J, Wu J.
    Wei Sheng Yan Jiu; 2003 Sep 05; 32(5):429-31. PubMed ID: 14650181
    [Abstract] [Full Text] [Related]

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  • 14. Development of a simple incubation system for metabolism studies with precision-cut liver slices.
    Dogterom P.
    Drug Metab Dispos; 1993 Sep 05; 21(4):699-704. PubMed ID: 8104130
    [Abstract] [Full Text] [Related]

  • 15. A species comparison of 14C-labeled 7-ethoxycoumarin metabolism in precision-cut liver slices from guinea pig and dog using a phosphor imaging system.
    Terada T, Kaneko H, Terashita S, Tozuka Z, Tokuma Y, Hata T.
    Res Commun Mol Pathol Pharmacol; 1996 Jan 05; 91(1):41-56. PubMed ID: 8824930
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  • 17. Cryopreservation of rat and mouse hepatocytes. II. Assessment of metabolic capacity using testosterone metabolism.
    Swales NJ, Johnson T, Caldwell J.
    Drug Metab Dispos; 1996 Nov 05; 24(11):1224-30. PubMed ID: 8937857
    [Abstract] [Full Text] [Related]

  • 18. Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies.
    van de Kerkhof EG, de Graaf IA, de Jager MH, Meijer DK, Groothuis GM.
    Drug Metab Dispos; 2005 Nov 05; 33(11):1613-20. PubMed ID: 16051733
    [Abstract] [Full Text] [Related]

  • 19. Effects of the anticancer dehydrotarplatin on cytochrome P450 and antioxidant enzymes in male rat tissues.
    Nannelli A, Messina A, Marini S, Trasciatti S, Longo V, Gervasi PG.
    Arch Toxicol; 2007 Jul 05; 81(7):479-87. PubMed ID: 17364183
    [Abstract] [Full Text] [Related]

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