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Pubmed for Handhelds

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Journal Abstract Search

114 related items for PubMed ID: 8824218

  • 21. 2,2',3,3',6,6'-hexachlorobiphenyl hydroxylation by active site mutants of cytochrome P450 2B1 and 2B11.
    Waller SC, He YA, Harlow GR, He YQ, Mash EA, Halpert JR.
    Chem Res Toxicol; 1999 Aug; 12(8):690-9. PubMed ID: 10458702
    [Abstract] [Full Text] [Related]

  • 22. Modification of serine 360 by a reactive intermediate of 17-alpha-ethynylestradiol results in mechanism-based inactivation of cytochrome P450s 2B1 and 2B6.
    Kent UM, Sridar C, Spahlinger G, Hollenberg PF.
    Chem Res Toxicol; 2008 Oct; 21(10):1956-63. PubMed ID: 18729327
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  • 23. Catalytic properties of an expressed cytochrome P450 2B1 from a Wistar-Kyoto rat liver cDNA library.
    Kobayashi Y, Strobel SM, Hopkins NE, Alworth WL, Halpert JR.
    Drug Metab Dispos; 1998 Oct; 26(10):1026-30. PubMed ID: 9763409
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  • 24. Alkylation of cellular macromolecules and target specificity of carcinogenic nitrosodialkylamines: metabolic activation by cytochromes P450 2B1 and 2E1.
    Shu L, Hollenberg PF.
    Carcinogenesis; 1997 Apr; 18(4):801-10. PubMed ID: 9111218
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  • 25. Directed evolution of mammalian cytochrome P450 2B1: mutations outside of the active site enhance the metabolism of several substrates, including the anticancer prodrugs cyclophosphamide and ifosfamide.
    Kumar S, Chen CS, Waxman DJ, Halpert JR.
    J Biol Chem; 2005 May 20; 280(20):19569-75. PubMed ID: 15774478
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  • 26. Mechanistic studies of cytochrome P450 2B1 inactivation by xanthates.
    Yanev SG, Kent UM, Roberts ES, Ballou DP, Hollenberg PF.
    Arch Biochem Biophys; 2000 Jun 01; 378(1):157-66. PubMed ID: 10871056
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  • 27. Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1.
    Goosen TC, Mills DE, Hollenberg PF.
    J Pharmacol Exp Ther; 2001 Jan 01; 296(1):198-206. PubMed ID: 11123381
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  • 30. Determinants of protein modification versus heme alkylation: inactivation of cytochrome P450 1A1 by 1-ethynylpyrene and phenylacetylene.
    Chan WK, Sui Z, Ortiz de Montellano PR.
    Chem Res Toxicol; 1993 Jan 01; 6(1):38-45. PubMed ID: 8448348
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  • 33. Escherichia coli expression of site-directed mutants of cytochrome P450 2B1 from six substrate recognition sites: substrate specificity and inhibitor selectivity studies.
    He YQ, He YA, Halpert JR.
    Chem Res Toxicol; 1995 Jun 01; 8(4):574-9. PubMed ID: 7548737
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  • 35. Substrate routes to the buried active site may vary among cytochromes P450: mutagenesis of the F-G region in P450 2B1.
    Scott EE, He YQ, Halpert JR.
    Chem Res Toxicol; 2002 Nov 01; 15(11):1407-13. PubMed ID: 12437331
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  • 36. The highly conserved Glu149 and Tyr190 residues contribute to peroxynitrite-mediated nitrotyrosine formation and the catalytic activity of cytochrome P450 2B1.
    Lin HL, Zhang H, Waskell L, Hollenberg PF.
    Chem Res Toxicol; 2005 Aug 01; 18(8):1203-10. PubMed ID: 16097793
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  • 38. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by n-propylxanthate.
    Kent UM, Yanev S, Hollenberg PF.
    Chem Res Toxicol; 1999 Apr 01; 12(4):317-22. PubMed ID: 10207119
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