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Journal Abstract Search

170 related items for PubMed ID: 8825124

  • 1. Specific inhibition of epidermal growth factor receptor tyrosine kinase by 4-anilinoquinazolines.
    Wakeling AE, Barker AJ, Davies DH, Brown DS, Green LR, Cartlidge SA, Woodburn JR.
    Breast Cancer Res Treat; 1996; 38(1):67-73. PubMed ID: 8825124
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  • 4. Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions.
    Smaill JB, Rewcastle GW, Loo JA, Greis KD, Chan OH, Reyner EL, Lipka E, Showalter HD, Vincent PW, Elliott WL, Denny WA.
    J Med Chem; 2000 Apr 06; 43(7):1380-97. PubMed ID: 10753475
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  • 8. Epidermal growth factor receptor tyrosine kinase. Investigation of catalytic mechanism, structure-based searching and discovery of a potent inhibitor.
    Ward WH, Cook PN, Slater AM, Davies DH, Holdgate GA, Green LR.
    Biochem Pharmacol; 1994 Aug 17; 48(4):659-66. PubMed ID: 8080438
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  • 9. 4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile inhibitors of epidermal growth factor receptor kinase and their bioisosteric relationship to the 4-anilino-6,7-dialkoxyquinazoline inhibitors.
    Wissner A, Berger DM, Boschelli DH, Floyd MB, Greenberger LM, Gruber BC, Johnson BD, Mamuya N, Nilakantan R, Reich MF, Shen R, Tsou HR, Upeslacis E, Wang YF, Wu B, Ye F, Zhang N.
    J Med Chem; 2000 Aug 24; 43(17):3244-56. PubMed ID: 10966743
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  • 10. 1,4-dioxane-fused 4-anilinoquinazoline as inhibitors of epidermal growth factor receptor kinase.
    Lee JY, Park YK, Seo SH, So IS, Chung HK, Yang BS, Lee SJ, Park H, Lee YS.
    Arch Pharm (Weinheim); 2001 Nov 24; 334(11):357-60. PubMed ID: 11822173
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  • 11. Tyrosine kinase inhibitors. 13. Structure-activity relationships for soluble 7-substituted 4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidines designed as inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor.
    Thompson AM, Murray DK, Elliott WL, Fry DW, Nelson JA, Showalter HD, Roberts BJ, Vincent PW, Denny WA.
    J Med Chem; 1997 Nov 21; 40(24):3915-25. PubMed ID: 9397172
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  • 12. Biochemical and antiproliferative properties of 4-[ar(alk)ylamino]pyridopyrimidines, a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor.
    Fry DW, Nelson JM, Slintak V, Keller PR, Rewcastle GW, Denny WA, Zhou H, Bridges AJ.
    Biochem Pharmacol; 1997 Oct 15; 54(8):877-87. PubMed ID: 9354588
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  • 14. Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors.
    Hennequin LF, Thomas AP, Johnstone C, Stokes ES, Plé PA, Lohmann JJ, Ogilvie DJ, Dukes M, Wedge SR, Curwen JO, Kendrew J, Lambert-van der Brempt C.
    J Med Chem; 1999 Dec 30; 42(26):5369-89. PubMed ID: 10639280
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  • 15. Structure-activity relationships for 4-anilinoquinazolines as potent inhibitors at the ATP binding site of the epidermal growth factor receptor in vitro.
    Denny WA, Rewcastle GW, Bridges AJ, Fry DW, Kraker AJ.
    Clin Exp Pharmacol Physiol; 1996 May 30; 23(5):424-7. PubMed ID: 8713682
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  • 17. Inhibition of the epidermal growth factor receptor tyrosine kinase by PD153035 in human A431 tumors in athymic nude mice.
    Kunkel MW, Hook KE, Howard CT, Przybranowski S, Roberts BJ, Elliott WL, Leopold WR.
    Invest New Drugs; 1996 May 30; 13(4):295-302. PubMed ID: 8824347
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  • 18. Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas.
    Li B, Chang CM, Yuan M, McKenna WG, Shu HK.
    Cancer Res; 2003 Nov 01; 63(21):7443-50. PubMed ID: 14612544
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  • 20. Tyrosine kinase inhibitors. 11. Soluble analogues of pyrrolo- and pyrazoloquinazolines as epidermal growth factor receptor inhibitors: synthesis, biological evaluation, and modeling of the mode of binding.
    Palmer BD, Trumpp-Kallmeyer S, Fry DW, Nelson JM, Showalter HD, Denny WA.
    J Med Chem; 1997 May 09; 40(10):1519-29. PubMed ID: 9154973
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