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338 related items for PubMed ID: 8828460
41. Identification of naturally occurring dominant negative mutants of thyroid hormone alpha 1 and beta 1 receptors in a human hepatocellular carcinoma cell line. Lin KH, Zhu XG, Shieh HY, Hsu HC, Chen ST, McPhie P, Cheng SY. Endocrinology; 1996 Oct; 137(10):4073-81. PubMed ID: 8828459 [Abstract] [Full Text] [Related]
42. Requirement of corepressor binding of thyroid hormone receptor mutants for dominant negative inhibition. Nagaya T, Fujieda M, Seo H. Biochem Biophys Res Commun; 1998 Jun 29; 247(3):620-3. PubMed ID: 9647743 [Abstract] [Full Text] [Related]
43. A novel TR beta mutation (R383H) in resistance to thyroid hormone syndrome predominantly impairs corepressor release and negative transcriptional regulation. Clifton-Bligh RJ, de Zegher F, Wagner RL, Collingwood TN, Francois I, Van Helvoirt M, Fletterick RJ, Chatterjee VK. Mol Endocrinol; 1998 May 29; 12(5):609-21. PubMed ID: 9605924 [Abstract] [Full Text] [Related]
44. Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone. Safer JD, Cohen RN, Hollenberg AN, Wondisford FE. J Biol Chem; 1998 Nov 13; 273(46):30175-82. PubMed ID: 9804773 [Abstract] [Full Text] [Related]
45. Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement. Williams GR, Zavacki AM, Harney JW, Brent GA. Endocrinology; 1994 Apr 13; 134(4):1888-96. PubMed ID: 8137757 [Abstract] [Full Text] [Related]
46. The thyroid hormone receptor variant alpha2 is a weak antagonist because it is deficient in interactions with nuclear receptor corepressors. Tagami T, Kopp P, Johnson W, Arseven OK, Jameson JL. Endocrinology; 1998 May 13; 139(5):2535-44. PubMed ID: 9564869 [Abstract] [Full Text] [Related]
47. Do clinical manifestations of resistance to thyroid hormone correlate with the functional alteration of the corresponding mutant thyroid hormone-beta receptors? Hayashi Y, Weiss RE, Sarne DH, Yen PM, Sunthornthepvarakul T, Marcocci C, Chin WW, Refetoff S. J Clin Endocrinol Metab; 1995 Nov 13; 80(11):3246-56. PubMed ID: 7593433 [Abstract] [Full Text] [Related]
48. A novel resistance to thyroid hormone associated with a new mutation (T329N) in the thyroid hormone receptor beta gene. Sarkissian G, Dace A, Mesmacque A, Bony-Trifunovic H, Malezet-Desmoulins C, Torresani J, Margotat A. Thyroid; 1999 Feb 13; 9(2):165-71. PubMed ID: 10090317 [Abstract] [Full Text] [Related]
49. Differential sensitivity of thyroid hormone receptor isoform homodimers and mutant heterodimers to hormone-induced dissociation from deoxyribonucleic acid: its role in dominant negative action. Zhu XG, McPhie P, Cheng SY. Endocrinology; 1997 Apr 13; 138(4):1456-63. PubMed ID: 9075702 [Abstract] [Full Text] [Related]
50. Thyroid hormone receptors repress estrogen receptor activation of a TRE. Graupner G, Zhang XK, Tzukerman M, Wills K, Hermann T, Pfahl M. Mol Endocrinol; 1991 Mar 13; 5(3):365-72. PubMed ID: 1653892 [Abstract] [Full Text] [Related]
51. Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers. Yen PM, Darling DS, Carter RL, Forgione M, Umeda PK, Chin WW. J Biol Chem; 1992 Feb 25; 267(6):3565-8. PubMed ID: 1740410 [Abstract] [Full Text] [Related]
52. An artificial thyroid hormone receptor mutant without DNA binding can have dominant negative effect. Liu RT, Suzuki S, Takeda T, DeGroot LJ. Mol Cell Endocrinol; 1996 Jun 18; 120(1):85-93. PubMed ID: 8809742 [Abstract] [Full Text] [Related]
53. Resistance to thyroid hormone due to a novel thyroid hormone receptor mutant in a patient with hypothyroidism secondary to lingual thyroid and functional characterization of the mutant receptor. Nakajima Y, Yamada M, Horiguchi K, Satoh T, Hashimoto K, Tokuhiro E, Onigata K, Mori M. Thyroid; 2010 Aug 18; 20(8):917-26. PubMed ID: 20615127 [Abstract] [Full Text] [Related]
54. Active repression by thyroid hormone receptor splicing variant alpha2 requires specific regulatory elements in the context of native triiodothyronine-regulated gene promoters. Farsetti A, Lazar J, Phyillaier M, Lippoldt R, Pontecorvi A, Nikodem VM. Endocrinology; 1997 Nov 18; 138(11):4705-12. PubMed ID: 9348197 [Abstract] [Full Text] [Related]
55. A novel mutation (E333D) in the thyroid hormone beta receptor causing resistance to thyroid hormone syndrome. Maraninchi M, Bourcigaux N, Dace A, El-Yazidi C, Malezet-Desmoulins C, Krempf M, Torresani J, Margotat A. Exp Clin Endocrinol Diabetes; 2006 Nov 18; 114(10):569-76. PubMed ID: 17177139 [Abstract] [Full Text] [Related]
56. General receptor for phosphoinositides 1, a novel repressor of thyroid hormone receptor action that prevents deoxyribonucleic acid binding. Poirier MB, Hamann G, Domingue ME, Roy M, Bardati T, Langlois MF. Mol Endocrinol; 2005 Aug 18; 19(8):1991-2005. PubMed ID: 15878955 [Abstract] [Full Text] [Related]
57. Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor. Zhang XY, Kaneshige M, Kamiya Y, Kaneshige K, McPhie P, Cheng SY. Mol Endocrinol; 2002 Sep 18; 16(9):2077-92. PubMed ID: 12198244 [Abstract] [Full Text] [Related]
58. Thyroid hormone receptor does not heterodimerize with the vitamin D receptor but represses vitamin D receptor-mediated transactivation. Raval-Pandya M, Freedman LP, Li H, Christakos S. Mol Endocrinol; 1998 Sep 18; 12(9):1367-79. PubMed ID: 9731705 [Abstract] [Full Text] [Related]
59. Second zinc finger mutants of thyroid hormone receptor selectively preserve DNA binding and heterodimerization but eliminate transcriptional activation. Nagaya T, Kopp P, Kitajima K, Jameson JL, Seo H. Biochem Biophys Res Commun; 1996 May 15; 222(2):524-30. PubMed ID: 8670238 [Abstract] [Full Text] [Related]