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Journal Abstract Search

297 related items for PubMed ID: 8831760

  • 21. Cinnamyl-3,4-dihydroxy-α-cyanocinnamate is a potent inhibitor of 5-lipoxygenase.
    Pergola C, Jazzar B, Rossi A, Buehring U, Luderer S, Dehm F, Northoff H, Sautebin L, Werz O.
    J Pharmacol Exp Ther; 2011 Jul; 338(1):205-13. PubMed ID: 21447614
    [Abstract] [Full Text] [Related]

  • 22. Pharmacological cross-reactivity between 5-lipoxygenase-activating protein, 5-lipoxygenase, and leukotriene C4 synthase.
    Gupta N, Nicholson DW, Ford-Hutchinson AW.
    Can J Physiol Pharmacol; 1997 Jul; 75(10-11):1212-9. PubMed ID: 9431445
    [Abstract] [Full Text] [Related]

  • 23. Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.
    Cusan C, Spalluto G, Prato M, Adams M, Bodensieck A, Bauer R, Tubaro A, Bernardi P, Da Ros T.
    Farmaco; 2005 Apr; 60(4):327-32. PubMed ID: 15848208
    [Abstract] [Full Text] [Related]

  • 24. Design and synthesis of pyrimido[4,5-b][1,4]benzothiazine derivatives, as potent 15-lipoxygenase inhibitors.
    Bakavoli M, Nikpour M, Rahimizadeh M, Saberi MR, Sadeghian H.
    Bioorg Med Chem; 2007 Mar 01; 15(5):2120-6. PubMed ID: 17210254
    [Abstract] [Full Text] [Related]

  • 25. Dual inhibition of 5-lipoxygenase/cyclooxygenase by a reconstituted homeopathic remedy; possible explanation for clinical efficacy and favourable gastrointestinal tolerability.
    Jäggi R, Würgler U, Grandjean F, Weiser M.
    Inflamm Res; 2004 Apr 01; 53(4):150-7. PubMed ID: 15060721
    [Abstract] [Full Text] [Related]

  • 26. 12/15-lipoxygenase inhibitors in diabetic nephropathy in the rat.
    Ma J, Natarajan R, LaPage J, Lanting L, Kim N, Becerra D, Clemmons B, Nast CC, Surya Prakash GK, Mandal M, Adler SG.
    Prostaglandins Leukot Essent Fatty Acids; 2005 Jan 01; 72(1):13-20. PubMed ID: 15589395
    [Abstract] [Full Text] [Related]

  • 27. 6-substituted purines as inhibitors of 15-lipoxygenase; a structure-activity study.
    Bråthe A, Gundersen LL, Malterud KE, Rise F.
    Arch Pharm (Weinheim); 2005 Apr 01; 338(4):159-66. PubMed ID: 15864785
    [Abstract] [Full Text] [Related]

  • 28. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
    Riendeau D, Percival MD, Boyce S, Brideau C, Charleson S, Cromlish W, Ethier D, Evans J, Falgueyret JP, Ford-Hutchinson AW, Gordon R, Greig G, Gresser M, Guay J, Kargman S, Léger S, Mancini JA, O'Neill G, Ouellet M, Rodger IW, Thérien M, Wang Z, Webb JK, Wong E, Chan CC.
    Br J Pharmacol; 1997 May 01; 121(1):105-17. PubMed ID: 9146894
    [Abstract] [Full Text] [Related]

  • 29. Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity.
    Hamer RR, Tegeler JJ, Kurtz ES, Allen RC, Bailey SC, Elliott ME, Hellyer L, Helsley GC, Przekop P, Freed BS, White J, Martin LL.
    J Med Chem; 1996 Jan 05; 39(1):246-52. PubMed ID: 8568814
    [Abstract] [Full Text] [Related]

  • 30. Substituted thiopyrano[2,3,4-c,d]indoles as potent, selective, and orally active inhibitors of 5-lipoxygenase. Synthesis and biological evaluation of L-691,816.
    Hutchinson JH, Riendeau D, Brideau C, Chan C, Delorme D, Denis D, Falgueyret JP, Fortin R, Guay J, Hamel P.
    J Med Chem; 1993 Sep 17; 36(19):2771-87. PubMed ID: 8410991
    [Abstract] [Full Text] [Related]

  • 31. Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases.
    Deschamps JD, Kenyon VA, Holman TR.
    Bioorg Med Chem; 2006 Jun 15; 14(12):4295-301. PubMed ID: 16500106
    [Abstract] [Full Text] [Related]

  • 32. 1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.
    Boehm JC, Smietana JM, Sorenson ME, Garigipati RS, Gallagher TF, Sheldrake PL, Bradbeer J, Badger AM, Laydon JT, Lee JC, Hillegass LM, Griswold DE, Breton JJ, Chabot-Fletcher MC, Adams JL.
    J Med Chem; 1996 Sep 27; 39(20):3929-37. PubMed ID: 8831759
    [Abstract] [Full Text] [Related]

  • 33. Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.
    Moreau A, Chen QH, Praveen Rao PN, Knaus EE.
    Bioorg Med Chem; 2006 Dec 01; 14(23):7716-27. PubMed ID: 16931030
    [Abstract] [Full Text] [Related]

  • 34. Pharmacology of PF-4191834, a novel, selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain.
    Masferrer JL, Zweifel BS, Hardy M, Anderson GD, Dufield D, Cortes-Burgos L, Pufahl RA, Graneto M.
    J Pharmacol Exp Ther; 2010 Jul 01; 334(1):294-301. PubMed ID: 20378715
    [Abstract] [Full Text] [Related]

  • 35. IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression.
    Spanbroek R, Hildner M, Köhler A, Müller A, Zintl F, Kühn H, Rådmark O, Samuelsson B, Habenicht AJ.
    Proc Natl Acad Sci U S A; 2001 Apr 24; 98(9):5152-7. PubMed ID: 11320251
    [Abstract] [Full Text] [Related]

  • 36. Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase.
    Hutchinson JH, Charleson S, Evans JF, Falgueyret JP, Hoogsteen K, Jones TR, Kargman S, Macdonald D, McFarlane CS, Nicholson DW.
    J Med Chem; 1995 Oct 27; 38(22):4538-47. PubMed ID: 7473582
    [Abstract] [Full Text] [Related]

  • 37. 5-lipoxygenase inhibitory activity of zileuton.
    Carter GW, Young PR, Albert DH, Bouska J, Dyer R, Bell RL, Summers JB, Brooks DW.
    J Pharmacol Exp Ther; 1991 Mar 27; 256(3):929-37. PubMed ID: 1848634
    [Abstract] [Full Text] [Related]

  • 38. [Influence of 2-aryl-3-halogen/3-hydroxy-1,4-naphthoquinones with salicylic and cinnamic acid partial structures on the arachidonic acid cascade].
    Richwien A, Wurm G.
    Pharmazie; 2004 Mar 27; 59(3):163-9. PubMed ID: 15074584
    [Abstract] [Full Text] [Related]

  • 39. Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors.
    Hong SH, Avis I, Vos MD, Martínez A, Treston AM, Mulshine JL.
    Cancer Res; 1999 May 01; 59(9):2223-8. PubMed ID: 10232612
    [Abstract] [Full Text] [Related]

  • 40. Pharmacodynamic and pharmacokinetic characterisation of RBx 7796: a novel 5-lipoxygenase inhibitor.
    Shirumalla RK, Sharma P, Dastidar SG, Paliwal JK, Kakar S, Varshney B, Singh Saini G, Sattigeri V, Salman M, Ray A.
    Inflamm Res; 2008 Mar 01; 57(3):135-43. PubMed ID: 18369577
    [Abstract] [Full Text] [Related]

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