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Journal Abstract Search


219 related items for PubMed ID: 8831817

  • 1. Mechanism-based inactivation of hepatic ethoxyresorufin O-dealkylation activity by naturally occurring coumarins.
    Cai Y, Baer-Dubowska W, Ashwood-Smith MJ, Ceska O, Tachibana S, DiGiovanni J.
    Chem Res Toxicol; 1996 Jun; 9(4):729-36. PubMed ID: 8831817
    [Abstract] [Full Text] [Related]

  • 2. Inhibition and inactivation of murine hepatic ethoxy- and pentoxyresorufin O-dealkylase by naturally occurring coumarins.
    Cai Y, Bennett D, Nair RV, Ceska O, Ashwood-Smith MJ, DiGiovanni J.
    Chem Res Toxicol; 1993 Jun; 6(6):872-9. PubMed ID: 8117927
    [Abstract] [Full Text] [Related]

  • 3. Bioactivation of 8-methoxypsoralen and irreversible inactivation of cytochrome P-450 in mouse liver microsomes: modification by monoclonal antibodies, inhibition of drug metabolism and distribution of covalent adducts.
    Mays DC, Hilliard JB, Wong DD, Chambers MA, Park SS, Gelboin HV, Gerber N.
    J Pharmacol Exp Ther; 1990 Aug; 254(2):720-31. PubMed ID: 2117068
    [Abstract] [Full Text] [Related]

  • 4. Inhibitory effects of naturally occurring coumarins on the metabolic activation of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured mouse keratinocytes.
    Cai Y, Baer-Dubowska W, Ashwood-Smith M, DiGiovanni J.
    Carcinogenesis; 1997 Jan; 18(1):215-22. PubMed ID: 9054609
    [Abstract] [Full Text] [Related]

  • 5. Activation of microsomal glutathione S-transferase and inhibition of cytochrome P450 1A1 activity as a model system for detecting protein alkylation by thiourea-containing compounds in rat liver microsomes.
    Onderwater RC, Commandeur JN, Menge WM, Vermeulen NP.
    Chem Res Toxicol; 1999 May; 12(5):396-402. PubMed ID: 10328749
    [Abstract] [Full Text] [Related]

  • 6. Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.
    Foroozesh M, Primrose G, Guo Z, Bell LC, Alworth WL, Guengerich FP.
    Chem Res Toxicol; 1997 Jan; 10(1):91-102. PubMed ID: 9074808
    [Abstract] [Full Text] [Related]

  • 7. Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice.
    Cai Y, Kleiner H, Johnston D, Dubowski A, Bostic S, Ivie W, DiGiovanni J.
    Carcinogenesis; 1997 Aug; 18(8):1521-7. PubMed ID: 9276625
    [Abstract] [Full Text] [Related]

  • 8. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Woodcroft KJ, Webb CD, Yao M, Weedon AC, Bend JR.
    Chem Res Toxicol; 1997 May; 10(5):589-99. PubMed ID: 9168258
    [Abstract] [Full Text] [Related]

  • 9. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin.
    Chun YJ, Ryu SY, Jeong TC, Kim MY.
    Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):389-93. PubMed ID: 11259321
    [Abstract] [Full Text] [Related]

  • 10. Induction and purification of cytochrome P450 1A1 from 3-methylcholanthrene-treated tilapia, Oreochromis niloticus x Oreochromis aureus.
    Ueng YF, Ueng TH.
    Arch Biochem Biophys; 1995 Oct 01; 322(2):347-56. PubMed ID: 7574707
    [Abstract] [Full Text] [Related]

  • 11. Mechanism-based inactivation of cytochrome P450 1A1 by N-aralkyl-1-aminobenzotriazoles in guinea pig kidney in vivo and in vitro: minimal effects on metabolism of arachidonic acid by renal P450-dependent monooxygenases.
    Knickle LC, Webb CD, House AA, Bend JR.
    J Pharmacol Exp Ther; 1993 Nov 01; 267(2):758-64. PubMed ID: 8246152
    [Abstract] [Full Text] [Related]

  • 12. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
    Hissink AM, Oudshoorn MJ, Van Ommen B, Haenen GR, Van Bladeren PJ.
    Chem Res Toxicol; 1996 Dec 01; 9(8):1249-56. PubMed ID: 8951226
    [Abstract] [Full Text] [Related]

  • 13. Mechanism-based inactivation of cytochrome P450 2B1 by 8-methoxypsoralen and several other furanocoumarins.
    Koenigs LL, Trager WF.
    Biochemistry; 1998 Sep 22; 37(38):13184-93. PubMed ID: 9748325
    [Abstract] [Full Text] [Related]

  • 14. Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.
    Munns AJ, De Voss JJ, Hooper WD, Dickinson RG, Gillam EM.
    Chem Res Toxicol; 1997 Sep 22; 10(9):1049-58. PubMed ID: 9305589
    [Abstract] [Full Text] [Related]

  • 15. Cytochrome P450 (P450) isoenzyme specific dealkylation of alkoxyresorufins in rat brain microsomes.
    Dhawan A, Parmar D, Dayal M, Seth PK.
    Mol Cell Biochem; 1999 Oct 22; 200(1-2):169-76. PubMed ID: 10569197
    [Abstract] [Full Text] [Related]

  • 16. Effect of p-amino-diphenyl ethers on hepatic microsomal cytochrome P450.
    Jiang H, Xuan G.
    Pharmazie; 2003 Sep 22; 58(9):654-6. PubMed ID: 14531464
    [Abstract] [Full Text] [Related]

  • 17. Naturally occurring coumarins inhibit human cytochromes P450 and block benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene DNA adduct formation in MCF-7 cells.
    Kleiner HE, Reed MJ, DiGiovanni J.
    Chem Res Toxicol; 2003 Mar 22; 16(3):415-22. PubMed ID: 12641443
    [Abstract] [Full Text] [Related]

  • 18. Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1.
    Goosen TC, Mills DE, Hollenberg PF.
    J Pharmacol Exp Ther; 2001 Jan 22; 296(1):198-206. PubMed ID: 11123381
    [Abstract] [Full Text] [Related]

  • 19. Effect of inducers of cytochrome P-450 on the metabolism of [3-14C]coumarin by rat hepatic microsomes.
    Peters MM, Walters DG, van Ommen B, van Bladeren PJ, Lake BG.
    Xenobiotica; 1991 Apr 22; 21(4):499-514. PubMed ID: 1897250
    [Abstract] [Full Text] [Related]

  • 20. The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5.
    Lin HL, Kent UM, Hollenberg PF.
    J Pharmacol Exp Ther; 2005 Apr 22; 313(1):154-64. PubMed ID: 15608076
    [Abstract] [Full Text] [Related]


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