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Journal Abstract Search

538 related items for PubMed ID: 8832876

  • 1. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells.
    Bischoff JR, Kirn DH, Williams A, Heise C, Horn S, Muna M, Ng L, Nye JA, Sampson-Johannes A, Fattaey A, McCormick F.
    Science; 1996 Oct 18; 274(5286):373-6. PubMed ID: 8832876
    [Abstract] [Full Text] [Related]

  • 2. Will a twist of viral fate lead to a new cancer treatment?
    Pennisi E.
    Science; 1996 Oct 18; 274(5286):342-3. PubMed ID: 8927990
    [No Abstract] [Full Text] [Related]

  • 3. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial.
    Nemunaitis J, Ganly I, Khuri F, Arseneau J, Kuhn J, McCarty T, Landers S, Maples P, Romel L, Randlev B, Reid T, Kaye S, Kirn D.
    Cancer Res; 2000 Nov 15; 60(22):6359-66. PubMed ID: 11103798
    [Abstract] [Full Text] [Related]

  • 4. p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection.
    Goodrum FD, Ornelles DA.
    J Virol; 1998 Dec 15; 72(12):9479-90. PubMed ID: 9811681
    [Abstract] [Full Text] [Related]

  • 5. A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer.
    Ganly I, Kirn D, Eckhardt G, Rodriguez GI, Soutar DS, Otto R, Robertson AG, Park O, Gulley ML, Heise C, Von Hoff DD, Kaye SB.
    Clin Cancer Res; 2000 Mar 15; 6(3):798-806. PubMed ID: 10741699
    [Abstract] [Full Text] [Related]

  • 6. p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication.
    Harada JN, Berk AJ.
    J Virol; 1999 Jul 15; 73(7):5333-44. PubMed ID: 10364280
    [Abstract] [Full Text] [Related]

  • 7. Oncolysis of human gastric cancers by an E1B 55 kDa-deleted YKL-1 adenovirus.
    Lee B, Choi J, Kim J, Kim JH, Joo CH, Cho YK, Kim YK, Lee H.
    Cancer Lett; 2002 Nov 28; 185(2):225-33. PubMed ID: 12169397
    [Abstract] [Full Text] [Related]

  • 8. Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein.
    Shen Y, Kitzes G, Nye JA, Fattaey A, Hermiston T.
    J Virol; 2001 May 28; 75(9):4297-307. PubMed ID: 11287579
    [Abstract] [Full Text] [Related]

  • 9. The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle.
    Goodrum FD, Ornelles DA.
    J Virol; 1997 Jan 28; 71(1):548-61. PubMed ID: 8985383
    [Abstract] [Full Text] [Related]

  • 10. E1B-55-kilodalton protein is not required to block p53-induced transcription during adenovirus infection.
    Hobom U, Dobbelstein M.
    J Virol; 2004 Jul 28; 78(14):7685-97. PubMed ID: 15220443
    [Abstract] [Full Text] [Related]

  • 11. Comparative effect of oncolytic adenoviruses with E1A-55 kDa or E1B-55 kDa deletions in malignant gliomas.
    Jiang H, Gomez-Manzano C, Alemany R, Medrano D, Alonso M, Bekele BN, Lin E, Conrad CC, Yung WK, Fueyo J.
    Neoplasia; 2005 Jan 28; 7(1):48-56. PubMed ID: 15720816
    [Abstract] [Full Text] [Related]

  • 12. Genetically modified adenoviruses against gliomas: from bench to bedside.
    Gomez-Manzano C, Yung WK, Alemany R, Fueyo J.
    Neurology; 2004 Aug 10; 63(3):418-26. PubMed ID: 15304571
    [Abstract] [Full Text] [Related]

  • 13. Evaluation of E1B gene-attenuated replicating adenoviruses for cancer gene therapy.
    Kim J, Cho JY, Kim JH, Jung KC, Yun CO.
    Cancer Gene Ther; 2002 Sep 10; 9(9):725-36. PubMed ID: 12189522
    [Abstract] [Full Text] [Related]

  • 14. Oncolytic activity of the E1B-55 kDa-deleted adenovirus ONYX-015 is independent of cellular p53 status in human malignant glioma xenografts.
    Geoerger B, Grill J, Opolon P, Morizet J, Aubert G, Terrier-Lacombe MJ, Bressac De-Paillerets B, Barrois M, Feunteun J, Kirn DH, Vassal G.
    Cancer Res; 2002 Feb 01; 62(3):764-72. PubMed ID: 11830531
    [Abstract] [Full Text] [Related]

  • 15. Highly augmented cytopathic effect of a fiber-mutant E1B-defective adenovirus for gene therapy of gliomas.
    Shinoura N, Yoshida Y, Tsunoda R, Ohashi M, Zhang W, Asai A, Kirino T, Hamada H.
    Cancer Res; 1999 Jul 15; 59(14):3411-6. PubMed ID: 10416603
    [Abstract] [Full Text] [Related]

  • 16. Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells.
    Rothmann T, Hengstermann A, Whitaker NJ, Scheffner M, zur Hausen H.
    J Virol; 1998 Dec 15; 72(12):9470-8. PubMed ID: 9811680
    [Abstract] [Full Text] [Related]

  • 17. Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity.
    O'Shea CC, Johnson L, Bagus B, Choi S, Nicholas C, Shen A, Boyle L, Pandey K, Soria C, Kunich J, Shen Y, Habets G, Ginzinger D, McCormick F.
    Cancer Cell; 2004 Dec 15; 6(6):611-23. PubMed ID: 15607965
    [Abstract] [Full Text] [Related]

  • 18. Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants.
    Hann B, Balmain A.
    J Virol; 2003 Nov 15; 77(21):11588-95. PubMed ID: 14557644
    [Abstract] [Full Text] [Related]

  • 19. Infection with E1B-mutant adenovirus stabilizes p53 but blocks p53 acetylation and activity through E1A.
    Savelyeva I, Dobbelstein M.
    Oncogene; 2011 Feb 17; 30(7):865-75. PubMed ID: 20935676
    [Abstract] [Full Text] [Related]

  • 20. p53-dependent cell death/apoptosis is required for a productive adenovirus infection.
    Hall AR, Dix BR, O'Carroll SJ, Braithwaite AW.
    Nat Med; 1998 Sep 17; 4(9):1068-72. PubMed ID: 9734403
    [Abstract] [Full Text] [Related]

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