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Journal Abstract Search

486 related items for PubMed ID: 8839057

  • 1. Bioactivation of a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, via glucuronidation. LC/MS/MS characterization of the GSH-glucuronide diconjugates.
    Tang W, Abbott FS.
    Chem Res Toxicol; 1996 Mar; 9(2):517-26. PubMed ID: 8839057
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  • 2. Identification and characterization of the glutathione and N-acetylcysteine conjugates of (E)-2-propyl-2,4-pentadienoic acid, a toxic metabolite of valproic acid, in rats and humans.
    Kassahun K, Farrell K, Abbott F.
    Drug Metab Dispos; 1991 Mar; 19(2):525-35. PubMed ID: 1676665
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  • 4. Characterization of thiol-conjugated metabolites of 2-propylpent-4-enoic acid (4-ene VPA), a toxic metabolite of valproic acid, by electrospray tandem mass spectrometry.
    Tang W, Abbott FS.
    J Mass Spectrom; 1996 Aug; 31(8):926-36. PubMed ID: 8799319
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  • 6. Gas chromatography/negative ion chemical ionization mass spectrometry and liquid chromatography/electrospray ionization tandem mass spectrometry quantitative profiling of N-acetylcysteine conjugates of valproic acid in urine: application in drug metabolism studies in humans.
    Gopaul SV, Farrell K, Abbott FS.
    J Mass Spectrom; 2000 Jun; 35(6):698-704. PubMed ID: 10862121
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  • 7. Partial characterization of biliary metabolites of pulegone by tandem mass spectrometry. Detection of glucuronide, glutathione, and glutathionyl glucuronide conjugates.
    Thomassen D, Pearson PG, Slattery JT, Nelson SD.
    Drug Metab Dispos; 1991 Jun; 19(5):997-1003. PubMed ID: 1686249
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  • 11. In vivo formation of the thiol conjugates of reactive metabolites of 4-ene VPA and its analog 4-pentenoic acid.
    Kassahun K, Abbott F.
    Drug Metab Dispos; 1993 Jun; 21(6):1098-106. PubMed ID: 7905390
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  • 13. Cytotoxicity of unsaturated metabolites of valproic acid and protection by vitamins C and E in glutathione-depleted rat hepatocytes.
    Jurima-Romet M, Abbott FS, Tang W, Huang HS, Whitehouse LW.
    Toxicology; 1996 Aug 01; 112(1):69-85. PubMed ID: 8792850
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  • 14. Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes.
    Surendradoss J, Chang TK, Abbott FS.
    Toxicol Appl Pharmacol; 2012 Nov 01; 264(3):413-22. PubMed ID: 22940460
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  • 15. Negative ion tandem mass spectrometry for the detection of glutathione conjugates.
    Dieckhaus CM, Fernández-Metzler CL, King R, Krolikowski PH, Baillie TA.
    Chem Res Toxicol; 2005 Apr 01; 18(4):630-8. PubMed ID: 15833023
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  • 16. Chemical and immunochemical comparison of protein adduct formation of four carboxylate drugs in rat liver and plasma.
    Bailey MJ, Dickinson RG.
    Chem Res Toxicol; 1996 Apr 01; 9(3):659-66. PubMed ID: 8728513
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  • 17. Metabolic activation of unsaturated derivatives of valproic acid. Identification of novel glutathione adducts formed through coenzyme A-dependent and -independent processes.
    Kassahun K, Hu P, Grillo MP, Davis MR, Jin L, Baillie TA.
    Chem Biol Interact; 1994 Mar 01; 90(3):253-75. PubMed ID: 8168173
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  • 18. Determination of enzyme kinetics and glutathione conjugates of chlortetracycline and chloroacetanilides using liquid chromatography-mass spectrometry.
    Farkas M, Berry JO, Aga DS.
    Analyst; 2007 Jul 01; 132(7):664-71. PubMed ID: 17592585
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  • 19. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
    Zhao SX, Dalvie DK, Kelly JM, Soglia JR, Frederick KS, Smith EB, Obach RS, Kalgutkar AS.
    Chem Res Toxicol; 2007 Nov 01; 20(11):1649-57. PubMed ID: 17907785
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