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143 related items for PubMed ID: 8863834

  • 1. Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation.
    Conklin BR, Herzmark P, Ishida S, Voyno-Yasenetskaya TA, Sun Y, Farfel Z, Bourne HR.
    Mol Pharmacol; 1996 Oct; 50(4):885-90. PubMed ID: 8863834
    [Abstract] [Full Text] [Related]

  • 2. Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha.
    Conklin BR, Farfel Z, Lustig KD, Julius D, Bourne HR.
    Nature; 1993 May 20; 363(6426):274-6. PubMed ID: 8387644
    [Abstract] [Full Text] [Related]

  • 3. Identification of a novel site within G protein alpha subunits important for specificity of receptor-G protein interaction.
    Heydorn A, Ward RJ, Jorgensen R, Rosenkilde MM, Frimurer TM, Milligan G, Kostenis E.
    Mol Pharmacol; 2004 Aug 20; 66(2):250-9. PubMed ID: 15266015
    [Abstract] [Full Text] [Related]

  • 4. Receptor-coupling properties of the invertebrate visual guanine nucleotide binding protein iGqalpha.
    Go L, Mitchell J.
    Cell Signal; 2007 Sep 20; 19(9):1919-27. PubMed ID: 17560078
    [Abstract] [Full Text] [Related]

  • 5. Molecular basis of receptor/G protein coupling selectivity studied by coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits.
    Kostenis E, Conklin BR, Wess J.
    Biochemistry; 1997 Feb 11; 36(6):1487-95. PubMed ID: 9063897
    [Abstract] [Full Text] [Related]

  • 6. G protein amino-terminal alpha i2/alpha s chimeras reveal amino acids important in regulating alpha s activity.
    Russell M, Johnson GL.
    Mol Pharmacol; 1993 Aug 11; 44(2):255-63. PubMed ID: 8394989
    [Abstract] [Full Text] [Related]

  • 7. Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling.
    Evanko DS, Thiyagarajan MM, Takida S, Wedegaertner PB.
    Cell Signal; 2005 Oct 11; 17(10):1218-28. PubMed ID: 16038796
    [Abstract] [Full Text] [Related]

  • 8. Coupling of metabotropic glutamate receptors 2 and 4 to G alpha 15, G alpha 16, and chimeric G alpha q/i proteins: characterization of new antagonists.
    Gomeza J, Mary S, Brabet I, Parmentier ML, Restituito S, Bockaert J, Pin JP.
    Mol Pharmacol; 1996 Oct 11; 50(4):923-30. PubMed ID: 8863838
    [Abstract] [Full Text] [Related]

  • 9. A surface-exposed region of G(salpha) in which substitutions decrease receptor-mediated activation and increase receptor affinity.
    Grishina G, Berlot CH.
    Mol Pharmacol; 2000 Jun 11; 57(6):1081-92. PubMed ID: 10825378
    [Abstract] [Full Text] [Related]

  • 10. Gq-mediated activation of c-Jun N-terminal kinase by the gastrin-releasing peptide-preferring bombesin receptor is inhibited upon costimulation of the Gs-coupled dopamine D1 receptor in COS-7 cells.
    Chan AS, Wong YH.
    Mol Pharmacol; 2005 Nov 11; 68(5):1354-64. PubMed ID: 16061771
    [Abstract] [Full Text] [Related]

  • 11. Incorporation of Galpha(z)-specific sequence at the carboxyl terminus increases the promiscuity of galpha(16) toward G(i)-coupled receptors.
    Mody SM, Ho MK, Joshi SA, Wong YH.
    Mol Pharmacol; 2000 Jan 11; 57(1):13-23. PubMed ID: 10617674
    [Abstract] [Full Text] [Related]

  • 12. Activating mutations in the NH2- and COOH-terminal moieties of the Gs alpha subunit have dominant phenotypes and distinguishable kinetics of adenylyl cyclase stimulation.
    Gupta SK, Dhanasekaran N, Heasley LE, Johnson GL.
    J Cell Biochem; 1991 Dec 11; 47(4):359-68. PubMed ID: 1665495
    [Abstract] [Full Text] [Related]

  • 13. Disruption of receptor-mediated activation of G protein by mutating a conserved arginine residue in the switch II region of the alpha subunit.
    Ho MK, Yung LY, Wong YH.
    J Neurochem; 1999 Nov 11; 73(5):2101-9. PubMed ID: 10537070
    [Abstract] [Full Text] [Related]

  • 14. Muscarinic M2 receptors directly activate Gq/11 and Gs G-proteins.
    Michal P, El-Fakahany EE, Dolezal V.
    J Pharmacol Exp Ther; 2007 Feb 11; 320(2):607-14. PubMed ID: 17065363
    [Abstract] [Full Text] [Related]

  • 15. G-protein betagamma-subunits contribute to the coupling specificity of the beta2-adrenergic receptor to G(s).
    Kühn B, Christel C, Wieland T, Schultz G, Gudermann T.
    Naunyn Schmiedebergs Arch Pharmacol; 2002 Mar 11; 365(3):231-41. PubMed ID: 11882919
    [Abstract] [Full Text] [Related]

  • 16. G(alpha)s levels regulate Xenopus laevis oocyte maturation.
    Romo X, Hinrichs MV, Guzmán L, Olate J.
    Mol Reprod Dev; 2002 Sep 11; 63(1):104-9. PubMed ID: 12211067
    [Abstract] [Full Text] [Related]

  • 17. A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity.
    Kostenis E, Martini L, Ellis J, Waldhoer M, Heydorn A, Rosenkilde MM, Norregaard PK, Jorgensen R, Whistler JL, Milligan G.
    J Pharmacol Exp Ther; 2005 Apr 11; 313(1):78-87. PubMed ID: 15615862
    [Abstract] [Full Text] [Related]

  • 18. Adrenergic stimulation of lacrimal protein secretion is mediated by G(q/11)alpha and G(s)alpha.
    Meneray MA, Fields TY.
    Curr Eye Res; 2000 Aug 11; 21(2):602-7. PubMed ID: 11148596
    [Abstract] [Full Text] [Related]

  • 19. A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor.
    Stables J, Green A, Marshall F, Fraser N, Knight E, Sautel M, Milligan G, Lee M, Rees S.
    Anal Biochem; 1997 Oct 01; 252(1):115-26. PubMed ID: 9324949
    [Abstract] [Full Text] [Related]

  • 20. Multiple regions of G alpha 16 contribute to the specificity of activation by the C5a receptor.
    Lee CH, Katz A, Simon MI.
    Mol Pharmacol; 1995 Feb 01; 47(2):218-23. PubMed ID: 7870028
    [Abstract] [Full Text] [Related]

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