These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

254 related items for PubMed ID: 8863835

  • 1. Mapping the functional domains of human recombinant phosphodiesterase 4A: structural requirements for catalytic activity and rolipram binding.
    Jacobitz S, McLaughlin MM, Livi GP, Burman M, Torphy TJ.
    Mol Pharmacol; 1996 Oct; 50(4):891-9. PubMed ID: 8863835
    [Abstract] [Full Text] [Related]

  • 2. Human recombinant phosphodiesterase 4B2B binds (R)-rolipram at a single site with two affinities.
    Rocque WJ, Tian G, Wiseman JS, Holmes WD, Zajac-Thompson I, Willard DH, Patel IR, Wisely GB, Clay WC, Kadwell SH, Hoffman CR, Luther MA.
    Biochemistry; 1997 Nov 18; 36(46):14250-61. PubMed ID: 9369498
    [Abstract] [Full Text] [Related]

  • 3. CDP840: a novel inhibitor of PDE-4.
    Perry MJ, O'Connell J, Walker C, Crabbe T, Baldock D, Russell A, Lumb S, Huang Z, Howat D, Allen R, Merriman M, Walls J, Daniel T, Hughes B, Laliberte F, Higgs GA, Owens RJ.
    Cell Biochem Biophys; 1998 Nov 18; 29(1-2):113-32. PubMed ID: 9631241
    [Abstract] [Full Text] [Related]

  • 4. Inhibitors of phosphodiesterase IV (PDE IV) increase acid secretion in rabbit isolated gastric glands: correlation between function and interaction with a high-affinity rolipram binding site.
    Barnette MS, Grous M, Cieslinski LB, Burman M, Christensen SB, Torphy TJ.
    J Pharmacol Exp Ther; 1995 Jun 18; 273(3):1396-402. PubMed ID: 7791113
    [Abstract] [Full Text] [Related]

  • 5. Dual inhibition of human type 4 phosphodiesterase isostates by (R, R)-(+/-)-methyl 3-acetyl-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-3- methyl-1-pyrrolidinecarboxylate.
    Tian G, Rocque WJ, Wiseman JS, Thompson IZ, Holmes WD, Domanico PL, Stafford JA, Feldman PL, Luther MA.
    Biochemistry; 1998 May 12; 37(19):6894-904. PubMed ID: 9578576
    [Abstract] [Full Text] [Related]

  • 6. Role of conserved histidines in catalytic activity and inhibitor binding of human recombinant phosphodiesterase 4A.
    Jacobitz S, Ryan MD, McLaughlin MM, Livi GP, DeWolf WE, Torphy TJ.
    Mol Pharmacol; 1997 Jun 12; 51(6):999-1006. PubMed ID: 9187266
    [Abstract] [Full Text] [Related]

  • 7. Detailed characterization of a purified type 4 phosphodiesterase, HSPDE4B2B: differentiation of high- and low-affinity (R)-rolipram binding.
    Rocque WJ, Holmes WD, Patel IR, Dougherty RW, Ittoop O, Overton L, Hoffman CR, Wisely GB, Willard DH, Luther MA.
    Protein Expr Purif; 1997 Mar 12; 9(2):191-202. PubMed ID: 9056484
    [Abstract] [Full Text] [Related]

  • 8. The ability of phosphodiesterase IV inhibitors to suppress superoxide production in guinea pig eosinophils is correlated with inhibition of phosphodiesterase IV catalytic activity.
    Barnette MS, Manning CD, Cieslinski LB, Burman M, Christensen SB, Torphy TJ.
    J Pharmacol Exp Ther; 1995 May 12; 273(2):674-9. PubMed ID: 7752069
    [Abstract] [Full Text] [Related]

  • 9. Biarylcarboxylic acids and -amides: inhibition of phosphodiesterase type IV versus [3H]rolipram binding activity and their relationship to emetic behavior in the ferret.
    Duplantier AJ, Biggers MS, Chambers RJ, Cheng JB, Cooper K, Damon DB, Eggler JF, Kraus KG, Marfat A, Masamune H, Pillar JS, Shirley JT, Umland JP, Watson JW.
    J Med Chem; 1996 Jan 05; 39(1):120-5. PubMed ID: 8568798
    [Abstract] [Full Text] [Related]

  • 10. Evidence that cyclic AMP phosphodiesterase inhibitors suppress interleukin-2 release from murine splenocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer.
    Souness JE, Houghton C, Sardar N, Withnall MT.
    Br J Pharmacol; 1997 Jun 05; 121(4):743-50. PubMed ID: 9208143
    [Abstract] [Full Text] [Related]

  • 11. Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors.
    Kelly JJ, Barnes PJ, Giembycz MA.
    Biochem J; 1996 Sep 01; 318 ( Pt 2)(Pt 2):425-36. PubMed ID: 8809029
    [Abstract] [Full Text] [Related]

  • 12. Inhibitor binding to type 4 phosphodiesterase (PDE4) assessed using [3H]piclamilast and [3H]rolipram.
    Zhao Y, Zhang HT, O'Donnell JM.
    J Pharmacol Exp Ther; 2003 May 01; 305(2):565-72. PubMed ID: 12704225
    [Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14. Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast.
    Torphy TJ, Stadel JM, Burman M, Cieslinski LB, McLaughlin MM, White JR, Livi GP.
    J Biol Chem; 1992 Jan 25; 267(3):1798-804. PubMed ID: 1309798
    [Abstract] [Full Text] [Related]

  • 15.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 16. Behavioural effects of selective PDE4 inhibitors in relation to inhibition of catalytic activity and competition for [3H]rolipram binding.
    Kapui Z, Bence J, Boronkay E, Mikus E, Urbán Szabó K, Baranyi A, Arányi P.
    Neurobiology (Bp); 1999 Jan 25; 7(1):71-3. PubMed ID: 10746252
    [No Abstract] [Full Text] [Related]

  • 17. Characterization of CHO-K1 cells stably expressing PDE-IV enzymes. Whole-cell cAMP determinations vs broken-cell enzymatic assays.
    Pon DJ, Plant M, Tkach J, Boulet L, Muise E, Allen RA, Rodger IW.
    Cell Biochem Biophys; 1998 Jan 25; 29(1-2):159-78. PubMed ID: 9631244
    [Abstract] [Full Text] [Related]

  • 18. Human phosphodiesterase 4A: characterization of full-length and truncated enzymes expressed in COS cells.
    Owens RJ, Catterall C, Batty D, Jappy J, Russell A, Smith B, O'Connell J, Perry MJ.
    Biochem J; 1997 Aug 15; 326 ( Pt 1)(Pt 1):53-60. PubMed ID: 9337850
    [Abstract] [Full Text] [Related]

  • 19. Expression and characterization of deletion recombinants of two cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE-3).
    He R, Komas N, Ekholm D, Murata T, Taira M, Hockman S, Degerman E, Manganiello VC.
    Cell Biochem Biophys; 1998 Aug 15; 29(1-2):89-111. PubMed ID: 9631240
    [Abstract] [Full Text] [Related]

  • 20. Pregnancy induces a modulation of the cAMP phosphodiesterase 4-conformers ratio in human myometrium: consequences for the utero-relaxant effect of PDE4-selective inhibitors.
    Méhats C, Tanguy G, Paris B, Robert B, Pernin N, Ferré F, Leroy MJ.
    J Pharmacol Exp Ther; 2000 Feb 15; 292(2):817-23. PubMed ID: 10640323
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 13.