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Journal Abstract Search

330 related items for PubMed ID: 8870981

  • 1. Pyridyloxobutylation of guanine residues by 4-[(acetoxymethyl)nitrosamino]-1-(3-pyridyl)-1-butanone generates substrates of O6-alkylguanine-DNA alkyltransferase.
    Liu XK, Spratt TE, Murphy SE, Peterson LA.
    Chem Res Toxicol; 1996 Sep; 9(6):949-53. PubMed ID: 8870981
    [Abstract] [Full Text] [Related]

  • 2. Pyridyloxobutyl adduct O6-[4-oxo-4-(3-pyridyl)butyl]guanine is present in 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-treated DNA and is a substrate for O6-alkylguanine-DNA alkyltransferase.
    Wang L, Spratt TE, Liu XK, Hecht SS, Pegg AE, Peterson LA.
    Chem Res Toxicol; 1997 May; 10(5):562-7. PubMed ID: 9168254
    [Abstract] [Full Text] [Related]

  • 3. Pyridyloxobutyl DNA adducts inhibit the repair of O6-methylguanine.
    Peterson LA, Liu XK, Hecht SS.
    Cancer Res; 1993 Jun 15; 53(12):2780-5. PubMed ID: 8504419
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of DNA oligonucleotides containing site-specifically incorporated O6-[4-oxo-4-(3-pyridyl)butyl]guanine and their reaction with O6-alkylguanine-DNA alkyltransferase.
    Wang L, Spratt TE, Pegg AE, Peterson LA.
    Chem Res Toxicol; 1999 Feb 15; 12(2):127-31. PubMed ID: 10027788
    [Abstract] [Full Text] [Related]

  • 5. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM, Kenney PM, Peterson LA.
    Chem Res Toxicol; 2003 Jan 15; 16(1):1-6. PubMed ID: 12693024
    [Abstract] [Full Text] [Related]

  • 6. The repair of the tobacco specific nitrosamine derived adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O6-alkylguanine-DNA alkyltransferase variants.
    Mijal RS, Thomson NM, Fleischer NL, Pauly GT, Moschel RC, Kanugula S, Fang Q, Pegg AE, Peterson LA.
    Chem Res Toxicol; 2004 Mar 15; 17(3):424-34. PubMed ID: 15025514
    [Abstract] [Full Text] [Related]

  • 7. O6-pyridyloxobutylguanine adducts contribute to the mutagenic properties of pyridyloxobutylating agents.
    Mijal RS, Loktionova NA, Vu CC, Pegg AE, Peterson LA.
    Chem Res Toxicol; 2005 Oct 15; 18(10):1619-25. PubMed ID: 16533027
    [Abstract] [Full Text] [Related]

  • 8. DNA sequence context affects repair of the tobacco-specific adduct O(6)-[4-Oxo-4-(3-pyridyl)butyl]guanine by human O(6)-alkylguanine-DNA alkyltransferases.
    Mijal RS, Kanugula S, Vu CC, Fang Q, Pegg AE, Peterson LA.
    Cancer Res; 2006 May 01; 66(9):4968-74. PubMed ID: 16651455
    [Abstract] [Full Text] [Related]

  • 9. A novel, sensitive assay for O6-methyl- and O6-ethylguanine in DNA, based on repair by the enzyme O6-alkylguanine-DNA-alkyltransferase in competition with an oligonucleotide containing O6-methylguanine.
    Souliotis VL, Kyrtopoulos SA.
    Cancer Res; 1989 Dec 15; 49(24 Pt 1):6997-7001. PubMed ID: 2684406
    [Abstract] [Full Text] [Related]

  • 10. Comparison of the rates of repair of O6-alkylguanines in DNA by rat liver and bacterial O6-alkylguanine-DNA alkyltransferase.
    Pegg AE, Scicchitano D, Dolan ME.
    Cancer Res; 1984 Sep 15; 44(9):3806-11. PubMed ID: 6378375
    [Abstract] [Full Text] [Related]

  • 11. Mass spectrometry based approach to study the kinetics of O6-alkylguanine DNA alkyltransferase-mediated repair of O6-pyridyloxobutyl-2'-deoxyguanosine adducts in DNA.
    Kotandeniya D, Murphy D, Seneviratne U, Guza R, Pegg A, Kanugula S, Tretyakova N.
    Chem Res Toxicol; 2011 Nov 21; 24(11):1966-75. PubMed ID: 21913712
    [Abstract] [Full Text] [Related]

  • 12. Interactions between methylating and pyridyloxobutylating agents in A/J mouse lungs: implications for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.
    Peterson LA, Thomson NM, Crankshaw DL, Donaldson EE, Kenney PJ.
    Cancer Res; 2001 Aug 01; 61(15):5757-63. PubMed ID: 11479212
    [Abstract] [Full Text] [Related]

  • 13. Development of a quantitative liquid chromatography/electrospray mass spectrometric assay for a mutagenic tobacco specific nitrosamine-derived DNA adduct, O6-[4-Oxo-4-(3-pyridyl)butyl]-2'-deoxyguanosine.
    Thomson NM, Mijal RS, Ziegel R, Fleischer NL, Pegg AE, Tretyakova NY, Peterson LA.
    Chem Res Toxicol; 2004 Dec 01; 17(12):1600-6. PubMed ID: 15606135
    [Abstract] [Full Text] [Related]

  • 14. The influence of repair pathways on the cytotoxicity and mutagenicity induced by the pyridyloxobutylation pathway of tobacco-specific nitrosamines.
    Li L, Perdigao J, Pegg AE, Lao Y, Hecht SS, Lindgren BR, Reardon JT, Sancar A, Wattenberg EV, Peterson LA.
    Chem Res Toxicol; 2009 Aug 01; 22(8):1464-72. PubMed ID: 19601657
    [Abstract] [Full Text] [Related]

  • 15. Specific labeling of O6-alkylguanine-DNA alkyltransferase by reaction with O6-(p-hydroxy[3H]methylbenzyl)guanine.
    Ciocco GM, Moschel RC, Chae MY, McLaughlin PJ, Zagon IS, Pegg AE.
    Cancer Res; 1995 Sep 15; 55(18):4085-91. PubMed ID: 7664284
    [Abstract] [Full Text] [Related]

  • 16. Formation and repair of pyridyloxobutyl DNA adducts and their relationship to tumor yield in A/J mice.
    Urban AM, Upadhyaya P, Cao Q, Peterson LA.
    Chem Res Toxicol; 2012 Oct 15; 25(10):2167-78. PubMed ID: 22928598
    [Abstract] [Full Text] [Related]

  • 17. Enhanced repair of O6-methylguanine DNA adducts in the liver of transgenic mice expressing the ada gene.
    Dumenco LL, Arce C, Norton K, Yun J, Wagner T, Gerson SL.
    Cancer Res; 1991 Jul 01; 51(13):3391-8. PubMed ID: 2054779
    [Abstract] [Full Text] [Related]

  • 18. Endogenous 5-methylcytosine protects neighboring guanines from N7 and O6-methylation and O6-pyridyloxobutylation by the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Ziegel R, Shallop A, Upadhyaya P, Jones R, Tretyakova N.
    Biochemistry; 2004 Jan 20; 43(2):540-9. PubMed ID: 14717610
    [Abstract] [Full Text] [Related]

  • 19. Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens.
    Wang M, Cheng G, Sturla SJ, Shi Y, McIntee EJ, Villalta PW, Upadhyaya P, Hecht SS.
    Chem Res Toxicol; 2003 May 20; 16(5):616-26. PubMed ID: 12755591
    [Abstract] [Full Text] [Related]

  • 20. Kinetics of O(6)-pyridyloxobutyl-2'-deoxyguanosine repair by human O(6)-alkylguanine DNA alkyltransferase.
    Kotandeniya D, Murphy D, Yan S, Park S, Seneviratne U, Koopmeiners JS, Pegg A, Kanugula S, Kassie F, Tretyakova N.
    Biochemistry; 2013 Jun 11; 52(23):4075-88. PubMed ID: 23683164
    [Abstract] [Full Text] [Related]

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