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Journal Abstract Search


151 related items for PubMed ID: 8874049

  • 1. Characterizing the DNA binding modes of a topoisomerase I-poisoning terbenzimidazole: evidence for both intercalative and minor groove binding properties.
    Pilch DS, Xu Z, Sun Q, Lavoie EJ, Liu LF, Geacintov NE, Breslauer KJ.
    Drug Des Discov; 1996 Apr; 13(3-4):115-33. PubMed ID: 8874049
    [Abstract] [Full Text] [Related]

  • 2. DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles.
    Xu Z, Li TK, Kim JS, LaVoie EJ, Breslauer KJ, Liu LF, Pilch DS.
    Biochemistry; 1998 Mar 10; 37(10):3558-66. PubMed ID: 9521677
    [Abstract] [Full Text] [Related]

  • 3. Aminoglycoside binding in the major groove of duplex RNA: the thermodynamic and electrostatic forces that govern recognition.
    Jin E, Katritch V, Olson WK, Kharatisvili M, Abagyan R, Pilch DS.
    J Mol Biol; 2000 Apr 21; 298(1):95-110. PubMed ID: 10756107
    [Abstract] [Full Text] [Related]

  • 4. Berenil [1,3-bis(4'-amidinophenyl)triazene] binding to DNA duplexes and to a RNA duplex: evidence for both intercalative and minor groove binding properties.
    Pilch DS, Kirolos MA, Liu X, Plum GE, Breslauer KJ.
    Biochemistry; 1995 Aug 08; 34(31):9962-76. PubMed ID: 7632695
    [Abstract] [Full Text] [Related]

  • 5. A terbenzimidazole that preferentially binds and conformationally alters structurally distinct DNA duplex domains: a potential mechanism for topoisomerase I poisoning.
    Pilch DS, Xu Z, Sun Q, LaVoie EJ, Liu LF, Breslauer KJ.
    Proc Natl Acad Sci U S A; 1997 Dec 09; 94(25):13565-70. PubMed ID: 9391066
    [Abstract] [Full Text] [Related]

  • 6. Minor groove-directed and intercalative ligand-DNA interactions in the poisoning of human DNA topoisomerase I by protoberberine analogs.
    Pilch DS, Yu C, Makhey D, LaVoie EJ, Srinivasan AR, Olson WK, Sauers RR, Breslauer KJ, Geacintov NE, Liu LF.
    Biochemistry; 1997 Oct 14; 36(41):12542-53. PubMed ID: 9376359
    [Abstract] [Full Text] [Related]

  • 7. Simultaneous binding of meso-tetrakis(N-methylpyridinium-4-yl)porphyrin and 4',6-diamidino-2-phenylindole at the minor grooves of poly(dA).poly(dT) and poly[d(A-T)(2)]: fluorescence resonance energy transfer between DNA bound drugs.
    Jin B, Lee HM, Lee YA, Ko JH, Kim C, Kim SK.
    J Am Chem Soc; 2005 Mar 02; 127(8):2417-24. PubMed ID: 15724996
    [Abstract] [Full Text] [Related]

  • 8. Interactions of intercalative and minor groove binding ligands with triplex poly(dA).[poly(dT)]2 and with duplex poly(dA).poly(dT) and poly[d(A-T)]2 studied by CD, LD, and normal absorption.
    Kim HK, Kim JM, Kim SK, Rodger A, Nordén B.
    Biochemistry; 1996 Jan 30; 35(4):1187-94. PubMed ID: 8573573
    [Abstract] [Full Text] [Related]

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  • 12. Characterization of the binding of YO to [poly(dA-dT)]2 and [poly(dG-dC)]2, and of the fluorescent properties of YO and YOYO complexed with the polynucleotides and double-stranded DNA.
    Larsson A, Carlsson C, Jonsson M.
    Biopolymers; 1995 Aug 30; 36(2):153-67. PubMed ID: 7492743
    [Abstract] [Full Text] [Related]

  • 13. Binding of nonintercalative antitumor drugs to DNA-polymers: structural effects of bisquaternary ammonium heterocycles.
    Burckhardt G, Zimmer C, Baguley B.
    J Biomol Struct Dyn; 1987 Apr 30; 4(5):813-31. PubMed ID: 2855923
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  • 14. Characterization of parazoanthoxanthin A binding to a series of natural and synthetic host DNA duplexes.
    Pasic L, Sepcic K, Turk T, Macek P, Poklar N.
    Arch Biochem Biophys; 2001 Sep 01; 393(1):132-42. PubMed ID: 11516170
    [Abstract] [Full Text] [Related]

  • 15. Interactions of the antiviral quinoxaline derivative 9-OH-B220 [2, 3-dimethyl-6-(dimethylaminoethyl)- 9-hydroxy-6H-indolo-[2, 3-b]quinoxaline] with duplex and triplex forms of synthetic DNA and RNA.
    Sehlstedt U, Aich P, Bergman J, Vallberg H, Nordén B, Gräslund A.
    J Mol Biol; 1998 Apr 24; 278(1):31-56. PubMed ID: 9571032
    [Abstract] [Full Text] [Related]

  • 16. Investigation of DNA binding modes for a symmetrical cyanine dye trication: effect of DNA sequence and structure.
    Cao R, Venezia CF, Armitage BA.
    J Biomol Struct Dyn; 2001 Jun 24; 18(6):844-56. PubMed ID: 11444373
    [Abstract] [Full Text] [Related]

  • 17. Binding of 2-azaanthraquinone derivatives to DNA and their interference with the activity of DNA topoisomerases in vitro.
    Burckhardt G, Walter A, Triebel H, Störl K, Simon H, Störl J, Opitz A, Roemer E, Zimmer C.
    Biochemistry; 1998 Apr 07; 37(14):4703-11. PubMed ID: 9537985
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  • 18. [Interaction of topotecan, DNA topoisomerase I inhibitor, with double-stranded polydeoxyribonucleotides. III. Binding at the minor groove].
    Strel'tsov SA, Mikheĭkin AL, Grokhovskiĭ SL, Oleĭnikov VA, Zhuze AL.
    Mol Biol (Mosk); 2002 Apr 07; 36(3):511-24. PubMed ID: 12068638
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  • 19. Synthesis, DNA-binding and cytotoxic properties of a bis(netropsin)-anthracenedione conjugate.
    Boitte N, Pommery N, Colson P, Houssier C, Waring MJ, Hénichart JP, Bailly C.
    Anticancer Drug Des; 1997 Sep 07; 12(6):481-501. PubMed ID: 9311557
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