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Journal Abstract Search

95 related items for PubMed ID: 8893037

  • 1. Metabolite kinetics of ondansetron in rat. Comparison of hepatic microsomes, isolated hepatocytes and liver slices, with in vivo disposition.
    Worboys PD, Brennan B, Bradbury A, Houston JB.
    Xenobiotica; 1996 Sep; 26(9):897-907. PubMed ID: 8893037
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  • 2. Scaling factors to relate drug metabolic clearance in hepatic microsomes, isolated hepatocytes, and the intact liver: studies with induced livers involving diazepam.
    Carlile DJ, Zomorodi K, Houston JB.
    Drug Metab Dispos; 1997 Aug; 25(8):903-11. PubMed ID: 9280396
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  • 3. In vivo disposition of caffeine predicted from hepatic microsomal and hepatocyte data.
    Hayes KA, Brennan B, Chenery R, Houston JB.
    Drug Metab Dispos; 1995 Mar; 23(3):349-53. PubMed ID: 7628300
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  • 8. Kinetics of drug metabolism in rat liver slices. II. Comparison of clearance by liver slices and freshly isolated hepatocytes.
    Worboys PD, Bradbury A, Houston JB.
    Drug Metab Dispos; 1996 Jun; 24(6):676-81. PubMed ID: 8781785
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  • 9. Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance.
    Brown HS, Griffin M, Houston JB.
    Drug Metab Dispos; 2007 Feb; 35(2):293-301. PubMed ID: 17132764
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  • 10. Sigmoidal kinetics of CYP3A substrates: an approach for scaling dextromethorphan metabolism in hepatic microsomes and isolated hepatocytes to predict in vivo clearance in rat.
    Witherow LE, Houston JB.
    J Pharmacol Exp Ther; 1999 Jul; 290(1):58-65. PubMed ID: 10381760
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  • 11. Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.
    Naritomi Y, Terashita S, Kimura S, Suzuki A, Kagayama A, Sugiyama Y.
    Drug Metab Dispos; 2001 Oct; 29(10):1316-24. PubMed ID: 11560875
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  • 12. Pharmacokinetics and metabolism of a cysteinyl leukotriene-1 receptor antagonist from the heterocyclic chromanol series in rats: in vitro-in vivo correlation, gender-related differences, isoform identification, and comparison with metabolism in human hepatic tissue.
    Kuperman AV, Kalgutkar AS, Marfat A, Chambers RJ, Liston TE.
    Drug Metab Dispos; 2001 Nov; 29(11):1403-9. PubMed ID: 11602515
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  • 13. Species differences in the metabolism of a potent HIV-1 reverse transcriptase inhibitor L-738,372. In vivo and in vitro studies in rats, dogs, monkeys, and human.
    Prueksaritanont T, Balani SK, Dwyer LM, Ellis JD, Kauffman LR, Varga SL, Pitzenberger SM, Theoharides AD.
    Drug Metab Dispos; 1995 Jul; 23(7):688-95. PubMed ID: 7587955
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  • 20. Kinetics of drug metabolism in rat liver slices. Rates of oxidation of ethoxycoumarin and tolbutamide, examples of high- and low-clearance compounds.
    Worboys PD, Bradbury A, Houston JB.
    Drug Metab Dispos; 1995 Mar; 23(3):393-7. PubMed ID: 7628306
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