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Journal Abstract Search

91 related items for PubMed ID: 8893837

  • 1. Synthesis of chiral 1-(2'-amino-2'-carboxyethyl)-1,4-dihydro-6,7-quinoxaline-2,3-diones: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor agonists and antagonists.
    Sun G, Uretsky NJ, Wallace LJ, Shams G, Weinstein DM, Miller DD.
    J Med Chem; 1996 Oct 25; 39(22):4430-8. PubMed ID: 8893837
    [Abstract] [Full Text] [Related]

  • 2. Heteroaryl analogues of AMPA. Synthesis and quantitative structure-activity relationships.
    Bang-Andersen B, Lenz SM, Skjaerbaek N, Søby KK, Hansen HO, Ebert B, Bøgesø KP, Krogsgaard-Larsen P.
    J Med Chem; 1997 Aug 29; 40(18):2831-42. PubMed ID: 9288165
    [Abstract] [Full Text] [Related]

  • 3. Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships.
    Falch E, Brehm L, Mikkelsen I, Johansen TN, Skjaerbaek N, Nielsen B, Stensbøl TB, Ebert B, Krogsgaard-Larsen P.
    J Med Chem; 1998 Jul 02; 41(14):2513-23. PubMed ID: 9651156
    [Abstract] [Full Text] [Related]

  • 4. AMPA receptor agonists: synthesis, protolytic properties, and pharmacology of 3-isothiazolol bioisosteres of glutamic acid.
    Matzen L, Engesgaard A, Ebert B, Didriksen M, Frølund B, Krogsgaard-Larsen P, Jaroszewski JW.
    J Med Chem; 1997 Feb 14; 40(4):520-7. PubMed ID: 9046343
    [Abstract] [Full Text] [Related]

  • 5. 5-(N-oxyaza)-7-substituted-1,4-dihydroquinoxaline-2,3-diones: novel, systemically active and broad spectrum antagonists for NMDA/glycine, AMPA, and kainate receptors.
    Cai SX, Huang JC, Espitia SA, Tran M, Ilyin VI, Hawkinson JE, Woodward RM, Weber E, Keana JF.
    J Med Chem; 1997 Oct 24; 40(22):3679-86. PubMed ID: 9357535
    [Abstract] [Full Text] [Related]

  • 6. AMPA receptor agonists: resolution, configurational assignment, and pharmacology of (+)-(S)- and (-)-(R)-2-amino-3-[3-hydroxy-5-(2-pyridyl)-isoxazol-4-yl]-propionic acid (2-Py-AMPA).
    Johansen TN, Ebert B, Falch E, Krogsgaard-Larsen P.
    Chirality; 1997 Oct 24; 9(3):274-80. PubMed ID: 9176992
    [Abstract] [Full Text] [Related]

  • 7. Design and synthesis of enantiomers of 3,5-dinitro-o-tyrosine: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid (AMPA) receptor antagonists.
    Sun G, Slavica M, Uretsky NJ, Wallace LJ, Shams G, Weinstein DM, Miller JC, Miller DD.
    J Med Chem; 1998 Mar 26; 41(7):1034-41. PubMed ID: 9544203
    [Abstract] [Full Text] [Related]

  • 8. SPD 502: a water-soluble and in vivo long-lasting AMPA antagonist with neuroprotective activity.
    Nielsen EO, Varming T, Mathiesen C, Jensen LH, Moller A, Gouliaev AH, Wätjen F, Drejer J.
    J Pharmacol Exp Ther; 1999 Jun 26; 289(3):1492-501. PubMed ID: 10336544
    [Abstract] [Full Text] [Related]

  • 9. 8-(1H-imidazol-1-yl)-7-nitro-4(5H)-imidazo[1,2-alpha]quinoxalinone and related compounds: synthesis and structure-activity relationships for the AMPA-type non-NMDA receptor.
    Ohmori J, Shimizu-Sasamata M, Okada M, Sakamoto S.
    J Med Chem; 1997 Jun 20; 40(13):2053-63. PubMed ID: 9207947
    [Abstract] [Full Text] [Related]

  • 10. N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
    Madsen U, Frydenvang K, Ebert B, Johansen TN, Brehm L, Krogsgaard-Larsen P.
    J Med Chem; 1996 Jan 05; 39(1):183-90. PubMed ID: 8568805
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of analogues of 7-chloro-4,5-dihydro-4- oxo-8-(1,2,4-triazol-4-yl)-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylic acid (TQX-173) as novel selective AMPA receptor antagonists.
    Catarzi D, Colotta V, Varano F, Calabri FR, Filacchioni G, Galli A, Costagli C, Carlà V.
    J Med Chem; 2004 Jan 01; 47(1):262-72. PubMed ID: 14695840
    [Abstract] [Full Text] [Related]

  • 12. The new 2,3-benzodiazepine derivative EGIS-8332 inhibits AMPA/kainate ion channels and cell death.
    Vegh MG, Kovács AD, Kovács G, Szabó G, Tihanyi K, Hársing LG, Lévay G.
    Neurochem Int; 2007 Feb 01; 50(3):555-63. PubMed ID: 17147974
    [Abstract] [Full Text] [Related]

  • 13. (2S,4R)-4-methylglutamic acid (SYM 2081): a selective, high-affinity ligand for kainate receptors.
    Zhou LM, Gu ZQ, Costa AM, Yamada KA, Mansson PE, Giordano T, Skolnick P, Jones KA.
    J Pharmacol Exp Ther; 1997 Jan 01; 280(1):422-7. PubMed ID: 8996224
    [Abstract] [Full Text] [Related]

  • 14. Novel AMPA receptor antagonists: synthesis and structure-activity relationships of 1-hydroxy-7-(1H-imidazol-1-yl)-6-nitro-2,3(1H,4H)- quinoxalinedione and related compounds.
    Ohmori J, Shimizu-Sasamata M, Okada M, Sakamoto S.
    J Med Chem; 1996 Sep 27; 39(20):3971-9. PubMed ID: 8831762
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido[3,4-f]- quinoxaline-2,3-dione and related quinoxalinediones: characterization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (and N-methyl-D-aspartate) receptor and anticonvulsant activity.
    Bigge CF, Malone TC, Boxer PA, Nelson CB, Ortwine DF, Schelkun RM, Retz DM, Lescosky LJ, Borosky SA, Vartanian MG.
    J Med Chem; 1995 Sep 15; 38(19):3720-40. PubMed ID: 7562904
    [Abstract] [Full Text] [Related]

  • 16. Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor.
    Cai SX, Kher SM, Zhou ZL, Ilyin V, Espitia SA, Tran M, Hawkinson JE, Woodward RM, Weber E, Keana JF.
    J Med Chem; 1997 Feb 28; 40(5):730-8. PubMed ID: 9057859
    [Abstract] [Full Text] [Related]

  • 17. Structure-activity studies of 6-(tetrazolylalkyl)-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 1. Effects of stereochemistry, chain length, and chain substitution.
    Ornstein PL, Arnold MB, Allen NK, Bleisch T, Borromeo PS, Lugar CW, Leander JD, Lodge D, Schoepp DD.
    J Med Chem; 1996 May 24; 39(11):2219-31. PubMed ID: 8667365
    [Abstract] [Full Text] [Related]

  • 18. Pharmacological characterization of the human ionotropic glutamate receptor subtype GluR3 stably expressed in mammalian cells.
    Varney MA, Rao SP, Jachec C, Deal C, Hess SD, Daggett LP, Lin F, Johnson EC, Veliçelebi G.
    J Pharmacol Exp Ther; 1998 Apr 24; 285(1):358-70. PubMed ID: 9536032
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA.
    Brehm L, Greenwood JR, Sløk FA, Holm MM, Nielsen B, Geneser U, Stensbøl TB, Bräuner-Osborne H, Begtrup M, Egebjerg J, Krogsgaard-Larsen P.
    Chirality; 2004 Aug 24; 16(7):452-66. PubMed ID: 15236343
    [Abstract] [Full Text] [Related]

  • 20. Trimetazidine modulates AMPA/kainate receptors in rat vestibular ganglion neurons.
    Dayanithi G, Desmadryl G, Travo C, Chabbert C, Sans A.
    Eur J Pharmacol; 2007 Nov 21; 574(1):8-14. PubMed ID: 17658512
    [Abstract] [Full Text] [Related]

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