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115 related items for PubMed ID: 8894110

  • 1. Inhibitors of farnesyl:protein transferase--a possible cancer chemotherapeutic.
    Scholten JD, Zimmerman K, Oxender M, Sebolt-Leopold J, Gowan R, Leonard D, Hupe DJ.
    Bioorg Med Chem; 1996 Sep; 4(9):1537-43. PubMed ID: 8894110
    [Abstract] [Full Text] [Related]

  • 2. Synergy between anions and farnesyldiphosphate competitive inhibitors of farnesyl:protein transferase.
    Scholten JD, Zimmerman KK, Oxender MG, Leonard D, Sebolt-Leopold J, Gowan R, Hupe DJ.
    J Biol Chem; 1997 Jul 18; 272(29):18077-81. PubMed ID: 9218438
    [Abstract] [Full Text] [Related]

  • 3. Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases.
    Omer CA, Kral AM, Diehl RE, Prendergast GC, Powers S, Allen CM, Gibbs JB, Kohl NE.
    Biochemistry; 1993 May 18; 32(19):5167-76. PubMed ID: 8494894
    [Abstract] [Full Text] [Related]

  • 4. From pure FPP to mixed FPP and CAAX competitive inhibitors of farnesyl protein transferase.
    Lannuzel M, Lamothe M, Schambel P, Etiévant C, Hill B, Perez M.
    Bioorg Med Chem Lett; 2003 Apr 17; 13(8):1459-62. PubMed ID: 12668012
    [Abstract] [Full Text] [Related]

  • 5. Photoaffinity labeling of yeast farnesyl protein transferase and enzymatic synthesis of a Ras protein incorporating a photoactive isoprenoid.
    Edelstein RL, Distefano MD.
    Biochem Biophys Res Commun; 1997 Jun 18; 235(2):377-82. PubMed ID: 9199201
    [Abstract] [Full Text] [Related]

  • 6. Phosphonate and bisphosphonate analogues of farnesyl pyrophosphate as potential inhibitors of farnesyl protein transferase.
    Holstein SA, Cermak DM, Wiemer DF, Lewis K, Hohl RJ.
    Bioorg Med Chem; 1998 Jun 18; 6(6):687-94. PubMed ID: 9681134
    [Abstract] [Full Text] [Related]

  • 7. Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.
    Lingham RB, Silverman KC, Jayasuriya H, Kim BM, Amo SE, Wilson FR, Rew DJ, Schaber MD, Bergstrom JD, Koblan KS, Graham SL, Kohl NE, Gibbs JB, Singh SB.
    J Med Chem; 1998 Nov 05; 41(23):4492-501. PubMed ID: 9804689
    [Abstract] [Full Text] [Related]

  • 8. Selection of potent inhibitors of farnesyl-protein transferase from a synthetic tetrapeptide combinatorial library.
    Wallace A, Koblan KS, Hamilton K, Marquis-Omer DJ, Miller PJ, Mosser SD, Omer CA, Schaber MD, Cortese R, Oliff A, Gibbs JB, Pessi A.
    J Biol Chem; 1996 Dec 06; 271(49):31306-11. PubMed ID: 8940136
    [Abstract] [Full Text] [Related]

  • 9. Identification of spinach farnesyl protein transferase. Dithiothreitol as an acceptor in vitro.
    Parmryd I, Shipton CA, Swiezewska E, Andersson B, Dallner G.
    Eur J Biochem; 1995 Dec 15; 234(3):723-31. PubMed ID: 8575428
    [Abstract] [Full Text] [Related]

  • 10. Farnesyl-derived inhibitors of ras farnesyl transferase.
    Kang MS, Stemerick DM, Zwolshen JH, Harry BS, Sunkara PS, Harrison BL.
    Biochem Biophys Res Commun; 1995 Dec 05; 217(1):245-9. PubMed ID: 8526918
    [Abstract] [Full Text] [Related]

  • 11. Biochemical and structural studies with prenyl diphosphate analogues provide insights into isoprenoid recognition by protein farnesyl transferase.
    Turek-Etienne TC, Strickland CL, Distefano MD.
    Biochemistry; 2003 Apr 08; 42(13):3716-24. PubMed ID: 12667062
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of farnesyl transferases from malignant and non-malignant cultured human lymphocytes by prenyl substrate analogues.
    Das NP, Allen CM.
    Biochem Biophys Res Commun; 1991 Dec 16; 181(2):729-35. PubMed ID: 1755854
    [Abstract] [Full Text] [Related]

  • 13. Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents.
    Cohen LH, Valentijn AR, Roodenburg L, Van Leeuwen RE, Huisman RH, Lutz RJ, Van der Marel GA, Van Boom JH.
    Biochem Pharmacol; 1995 Mar 15; 49(6):839-45. PubMed ID: 7702642
    [Abstract] [Full Text] [Related]

  • 14. Oreganic acid, a potent inhibitor of ras farnesyl-protein transferase.
    Silverman KC, Jayasuriya H, Cascales C, Vilella D, Bills GF, Jenkins RG, Singh SB, Lingham RB.
    Biochem Biophys Res Commun; 1997 Mar 17; 232(2):478-81. PubMed ID: 9125205
    [Abstract] [Full Text] [Related]

  • 15. A new class of highly potent farnesyl diphosphate-competitive inhibitors of farnesyltransferase.
    Aoyama T, Satoh T, Yonemoto M, Shibata J, Nonoshita K, Arai S, Kawakami K, Iwasawa Y, Sano H, Tanaka K, Monden Y, Kodera T, Arakawa H, Suzuki-Takahashi I, Kamei T, Tomimoto K.
    J Med Chem; 1998 Jan 15; 41(2):143-7. PubMed ID: 9457237
    [No Abstract] [Full Text] [Related]

  • 16. Steady-state kinetic mechanism of Ras farnesyl:protein transferase.
    Pompliano DL, Rands E, Schaber MD, Mosser SD, Anthony NJ, Gibbs JB.
    Biochemistry; 1992 Apr 21; 31(15):3800-7. PubMed ID: 1567835
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and evaluation of a novel series of farnesyl protein transferase inhibitors as non-peptidic CAAX tetrapeptide analogues.
    Perez M, Maraval C, Dumond S, Lamothe M, Schambel P, Etiévant C, Hill B.
    Bioorg Med Chem Lett; 2003 Apr 17; 13(8):1455-8. PubMed ID: 12668011
    [Abstract] [Full Text] [Related]

  • 18. Selective modification of CaaX peptides with ortho-substituted anilinogeranyl lipids by protein farnesyl transferase: competitive substrates and potent inhibitors from a library of farnesyl diphosphate analogues.
    Troutman JM, Subramanian T, Andres DA, Spielmann HP.
    Biochemistry; 2007 Oct 09; 46(40):11310-21. PubMed ID: 17854205
    [Abstract] [Full Text] [Related]

  • 19. Functional consequence of mutating conserved residues of the yeast farnesyl-protein transferase beta-subunit Ram1(Dpr1).
    Kurth DD, Farh L, Deschenes RJ.
    Biochemistry; 1997 Dec 16; 36(50):15932-9. PubMed ID: 9398327
    [Abstract] [Full Text] [Related]

  • 20. Aromatic farnesyl diphosphate analogues: vinyl triflate-mediated synthesis and preliminary enzymatic evaluation.
    Zhou C, Shao Y, Gibbs RA.
    Bioorg Med Chem Lett; 2002 May 20; 12(10):1417-20. PubMed ID: 11992789
    [Abstract] [Full Text] [Related]

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