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Journal Abstract Search

121 related items for PubMed ID: 8894306

  • 1. N alpha-acetylcarnosine is a prodrug of L-carnosine in ophthalmic application as antioxidant.
    Babizhayev MA, Yermakova VN, Sakina NL, Evstigneeva RP, Rozhkova EA, Zheltukhina GA.
    Clin Chim Acta; 1996 Oct 15; 254(1):1-21. PubMed ID: 8894306
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  • 2. The natural histidine-containing dipeptide Nalpha-acetylcarnosine as an antioxidant for ophthalmic use.
    Babizhayev MA, Yermakova VN, Semiletov YA, Deyev AI.
    Biochemistry (Mosc); 2000 May 15; 65(5):588-98. PubMed ID: 10851037
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  • 3. Analysis of lipid peroxidation and electron microscopic survey of maturation stages during human cataractogenesis: pharmacokinetic assay of Can-C N-acetylcarnosine prodrug lubricant eye drops for cataract prevention.
    Babizhayev MA.
    Drugs R D; 2005 May 15; 6(6):345-69. PubMed ID: 16274259
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  • 4. Potentiation of intraocular absorption and drug metabolism of N-acetylcarnosine lubricant eye drops: drug interaction with sight threatening lipid peroxides in the treatment for age-related eye diseases.
    Babizhayev MA.
    Drug Metabol Drug Interact; 2009 May 15; 24(2-4):275-323. PubMed ID: 20408504
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  • 7. Bioactivation antioxidant and transglycating properties of N-acetylcarnosine autoinduction prodrug of a dipeptide L-carnosine in mucoadhesive drug delivery eye-drop formulation: powerful eye health application technique and therapeutic platform.
    Babizhayev MA.
    Drug Test Anal; 2012 Jun 15; 4(6):468-85. PubMed ID: 21416634
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  • 8. N-acetylcarnosine lubricant eyedrops possess all-in-one universal antioxidant protective effects of L-carnosine in aqueous and lipid membrane environments, aldehyde scavenging, and transglycation activities inherent to cataracts: a clinical study of the new vision-saving drug N-acetylcarnosine eyedrop therapy in a database population of over 50,500 patients.
    Babizhayev MA, Micans P, Guiotto A, Kasus-Jacobi A.
    Am J Ther; 2009 Jun 15; 16(6):517-33. PubMed ID: 19487926
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  • 9. Telomere Attrition in Human Lens Epithelial Cells Associated with Oxidative Stress Provide a New Therapeutic Target for the Treatment, Dissolving and Prevention of Cataract with N-Acetylcarnosine Lubricant Eye Drops. Kinetic, Pharmacological and Activity-Dependent Separation of Therapeutic Targeting: Transcorneal Penetration and Delivery of L-Carnosine in the Aqueous Humor and Hormone-Like Hypothalamic Antiaging Effects of the Instilled Ophthalmic Drug Through a Safe Eye Medication Technique.
    Babizhayev MA, Yegorov YE.
    Recent Pat Drug Deliv Formul; 2016 Jun 15; 10(2):82-129. PubMed ID: 26084629
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  • 10. N-Acetylcarnosine sustained drug delivery eye drops to control the signs of ageless vision: glare sensitivity, cataract amelioration and quality of vision currently available treatment for the challenging 50,000-patient population.
    Babizhayev MA, Burke L, Micans P, Richer SP.
    Clin Interv Aging; 2009 Jun 15; 4():31-50. PubMed ID: 19503764
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  • 13. Mitochondria induce oxidative stress, generation of reactive oxygen species and redox state unbalance of the eye lens leading to human cataract formation: disruption of redox lens organization by phospholipid hydroperoxides as a common basis for cataract disease.
    Babizhayev MA.
    Cell Biochem Funct; 2011 Apr 15; 29(3):183-206. PubMed ID: 21381059
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  • 14. Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool to manage age-related cataracts in human and in canine eyes.
    Babizhayev MA, Deyev AI, Yermakova VN, Brikman IV, Bours J.
    Drugs R D; 2004 Apr 15; 5(3):125-39. PubMed ID: 15139774
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  • 15. Biomarkers and special features of oxidative stress in the anterior segment of the eye linked to lens cataract and the trabecular meshwork injury in primary open-angle glaucoma: challenges of dual combination therapy with N-acetylcarnosine lubricant eye drops and oral formulation of nonhydrolyzed carnosine.
    Babizhayev MA.
    Fundam Clin Pharmacol; 2012 Feb 15; 26(1):86-117. PubMed ID: 21883446
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  • 17. Novel intraocular and systemic absorption drug delivery and efficacy of N-acetylcarnosine lubricant eye drops or carcinine biologics in pharmaceutical usage and therapeutic vision care.
    Babizhayev MA, Khoroshilova-Maslova IP, Kasus-Jacobi A.
    Fundam Clin Pharmacol; 2012 Oct 15; 26(5):644-78. PubMed ID: 21793899
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  • 18. Ocular pharmacokinetics of carnosine 5% eye drops following topical application in rabbit.
    Tianyang Z, Ling Z, Liya W, Junjie Z.
    J Ocul Pharmacol Ther; 2011 Feb 15; 27(1):93-7. PubMed ID: 20085487
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  • 20. Generation of reactive oxygen species in the anterior eye segment. Synergistic codrugs of N-acetylcarnosine lubricant eye drops and mitochondria-targeted antioxidant act as a powerful therapeutic platform for the treatment of cataracts and primary open-angle glaucoma.
    Babizhayev MA.
    BBA Clin; 2016 Dec 15; 6():49-68. PubMed ID: 27413694
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