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Journal Abstract Search

110 related items for PubMed ID: 8894493

  • 1. Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1 and identification of insulin receptor substrate-2.
    Kadowaki T, Tamemoto H, Tobe K, Terauchi Y, Ueki K, Kaburagi Y, Yamauchi T, Satoh S, Sekihara H, Aizawa S, Yazaki Y.
    Diabet Med; 1996 Sep; 13(9 Suppl 6):S103-8. PubMed ID: 8894493
    [Abstract] [Full Text] [Related]

  • 2. Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.
    Tamemoto H, Kadowaki T, Tobe K, Yagi T, Sakura H, Hayakawa T, Terauchi Y, Ueki K, Kaburagi Y, Satoh S.
    Nature; 1994 Nov 10; 372(6502):182-6. PubMed ID: 7969452
    [Abstract] [Full Text] [Related]

  • 3. Insulin signalling and insulin actions in the muscles and livers of insulin-resistant, insulin receptor substrate 1-deficient mice.
    Yamauchi T, Tobe K, Tamemoto H, Ueki K, Kaburagi Y, Yamamoto-Honda R, Takahashi Y, Yoshizawa F, Aizawa S, Akanuma Y, Sonenberg N, Yazaki Y, Kadowaki T.
    Mol Cell Biol; 1996 Jun 10; 16(6):3074-84. PubMed ID: 8649419
    [Abstract] [Full Text] [Related]

  • 4. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.
    Araki E, Lipes MA, Patti ME, Brüning JC, Haag B, Johnson RS, Kahn CR.
    Nature; 1994 Nov 10; 372(6502):186-90. PubMed ID: 7526222
    [Abstract] [Full Text] [Related]

  • 5. Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.
    Kubota N, Tobe K, Terauchi Y, Eto K, Yamauchi T, Suzuki R, Tsubamoto Y, Komeda K, Nakano R, Miki H, Satoh S, Sekihara H, Sciacchitano S, Lesniak M, Aizawa S, Nagai R, Kimura S, Akanuma Y, Taylor SI, Kadowaki T.
    Diabetes; 2000 Nov 10; 49(11):1880-9. PubMed ID: 11078455
    [Abstract] [Full Text] [Related]

  • 6. Identification of a 190-kDa protein as a novel substrate for the insulin receptor kinase functionally similar to insulin receptor substrate-1.
    Tobe K, Tamemoto H, Yamauchi T, Aizawa S, Yazaki Y, Kadowaki T.
    J Biol Chem; 1995 Mar 17; 270(11):5698-701. PubMed ID: 7534300
    [Abstract] [Full Text] [Related]

  • 7. Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease.
    Terauchi Y, Iwamoto K, Tamemoto H, Komeda K, Ishii C, Kanazawa Y, Asanuma N, Aizawa T, Akanuma Y, Yasuda K, Kodama T, Tobe K, Yazaki Y, Kadowaki T.
    J Clin Invest; 1997 Mar 01; 99(5):861-6. PubMed ID: 9062343
    [Abstract] [Full Text] [Related]

  • 8. Signal transduction mechanism of insulin and insulin-like growth factor-1.
    Kadowaki T, Tobe K, Honda-Yamamoto R, Tamemoto H, Kaburagi Y, Momomura K, Ueki K, Takahashi Y, Yamauchi T, Akanuma Y, Yazaki Y.
    Endocr J; 1996 Oct 01; 43 Suppl():S33-41. PubMed ID: 9076340
    [Abstract] [Full Text] [Related]

  • 9. ATP-sensitive K+ channel-mediated glucose uptake is independent of IRS-1/phosphatidylinositol 3-kinase signaling.
    Minami K, Morita M, Saraya A, Yano H, Terauchi Y, Miki T, Kuriyama T, Kadowaki T, Seino S.
    Am J Physiol Endocrinol Metab; 2003 Dec 01; 285(6):E1289-96. PubMed ID: 12933351
    [Abstract] [Full Text] [Related]

  • 10. Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis.
    Fantin VR, Wang Q, Lienhard GE, Keller SR.
    Am J Physiol Endocrinol Metab; 2000 Jan 01; 278(1):E127-33. PubMed ID: 10644546
    [Abstract] [Full Text] [Related]

  • 11. Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.
    Valverde AM, Lorenzo M, Pons S, White MF, Benito M.
    Mol Endocrinol; 1998 May 01; 12(5):688-97. PubMed ID: 9605931
    [Abstract] [Full Text] [Related]

  • 12. Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.
    Kido Y, Burks DJ, Withers D, Bruning JC, Kahn CR, White MF, Accili D.
    J Clin Invest; 2000 Jan 01; 105(2):199-205. PubMed ID: 10642598
    [Abstract] [Full Text] [Related]

  • 13. Disruption of IRS-2 causes type 2 diabetes in mice.
    Withers DJ, Gutierrez JS, Towery H, Burks DJ, Ren JM, Previs S, Zhang Y, Bernal D, Pons S, Shulman GI, Bonner-Weir S, White MF.
    Nature; 1998 Feb 26; 391(6670):900-4. PubMed ID: 9495343
    [Abstract] [Full Text] [Related]

  • 14. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.
    Withers DJ, Burks DJ, Towery HH, Altamuro SL, Flint CL, White MF.
    Nat Genet; 1999 Sep 26; 23(1):32-40. PubMed ID: 10471495
    [Abstract] [Full Text] [Related]

  • 15. Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action.
    Bard-Chapeau EA, Hevener AL, Long S, Zhang EE, Olefsky JM, Feng GS.
    Nat Med; 2005 May 26; 11(5):567-71. PubMed ID: 15821749
    [Abstract] [Full Text] [Related]

  • 16. Antiinsulin receptor autoantibodies induce insulin receptors to constitutively associate with insulin receptor substrate-1 and -2 and cause severe cell resistance to both insulin and insulin-like growth factor I.
    Auclair M, Vigouroux C, Desbois-Mouthon C, Deibener J, Kaminski P, Lascols O, Cherqui G, Capeau J, Caron M.
    J Clin Endocrinol Metab; 1999 Sep 26; 84(9):3197-206. PubMed ID: 10487687
    [Abstract] [Full Text] [Related]

  • 17. Receptors for insulin and insulin-like growth factor-1 and insulin receptor substrate-1 mediate pathways that regulate islet function.
    Kulkarni RN.
    Biochem Soc Trans; 2002 Apr 26; 30(2):317-22. PubMed ID: 12023872
    [Abstract] [Full Text] [Related]

  • 18. Restored insulin-sensitivity in IRS-1-deficient mice treated by adenovirus-mediated gene therapy.
    Ueki K, Yamauchi T, Tamemoto H, Tobe K, Yamamoto-Honda R, Kaburagi Y, Akanuma Y, Yazaki Y, Aizawa S, Nagai R, Kadowaki T.
    J Clin Invest; 2000 May 26; 105(10):1437-45. PubMed ID: 10811851
    [Abstract] [Full Text] [Related]

  • 19. Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice.
    Carvalho-Filho MA, Ueno M, Carvalheira JB, Velloso LA, Saad MJ.
    Am J Physiol Endocrinol Metab; 2006 Sep 26; 291(3):E476-82. PubMed ID: 16638822
    [Abstract] [Full Text] [Related]

  • 20. Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury.
    Kubota T, Kubota N, Moroi M, Terauchi Y, Kobayashi T, Kamata K, Suzuki R, Tobe K, Namiki A, Aizawa S, Nagai R, Kadowaki T, Yamaguchi T.
    Circulation; 2003 Jun 24; 107(24):3073-80. PubMed ID: 12810606
    [Abstract] [Full Text] [Related]

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