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Journal Abstract Search

268 related items for PubMed ID: 8894517

  • 1. Metabolism of an atypical antipsychotic agent, 3-[4-[4-(6-fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2, 5,5-trimethyl-4-thiazolidinone (HP236).
    Mutlib AE, Jurcak J, Hrib N.
    Drug Metab Dispos; 1996 Oct; 24(10):1139-50. PubMed ID: 8894517
    [Abstract] [Full Text] [Related]

  • 2. Structure-activity relationships of a series of novel (piperazinylbutyl)thiazolidinone antipsychotic agents related to 3-[4-[4-(6-fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2,5,5- trimethyl-4-thiazolidinone maleate.
    Hrib NJ, Jurcak JG, Bregna DE, Burgher KL, Hartman HB, Kafka S, Kerman LL, Kongsamut S, Roehr JE, Szewczak MR, Woods-Kettelberger AT, Corbett R.
    J Med Chem; 1996 Sep 27; 39(20):4044-57. PubMed ID: 8831770
    [Abstract] [Full Text] [Related]

  • 3. Metabolism and excretion of a new antipsychotic drug, ziprasidone, in humans.
    Prakash C, Kamel A, Gummerus J, Wilner K.
    Drug Metab Dispos; 1997 Jul 27; 25(7):863-72. PubMed ID: 9224781
    [Abstract] [Full Text] [Related]

  • 4. Application of hyphenated LC/NMR and LC/MS techniques in rapid identification of in vitro and in vivo metabolites of iloperidone.
    Mutlib AE, Strupczewski JT, Chesson SM.
    Drug Metab Dispos; 1995 Sep 27; 23(9):951-64. PubMed ID: 8565786
    [Abstract] [Full Text] [Related]

  • 5. Metabolism and excretion of the novel antipsychotic drug ziprasidone in rats after oral administration of a mixture of 14C- and 3H-labeled ziprasidone.
    Prakash C, Kamel A, Anderson W, Howard H.
    Drug Metab Dispos; 1997 Feb 27; 25(2):206-18. PubMed ID: 9029052
    [Abstract] [Full Text] [Related]

  • 6. 3-[4-[1-(6-Fluorobenzo[b]thiophen-3-yl)-4-piperazinyl]butyl]- 2,5,5-trimethyl-4-thiazolidinone: a new atypical antipsychotic agent for the treatment of schizophrenia.
    Hrib NJ, Jurcak JG, Bregna DE, Dunn RW, Geyer HM, Hartman HB, Roehr JE, Rogers KL, Rush DK, Szczepanik AM.
    J Med Chem; 1992 Jul 10; 35(14):2712-5. PubMed ID: 1353116
    [No Abstract] [Full Text] [Related]

  • 7. Orally active inhibitors of human leukocyte elastase. III. Identification and characterization of metabolites of L-694,458 by liquid chromatography-tandem mass spectrometry.
    Luffer-Atlas D, Vincent SH, Painter SK, Arison BH, Stearns RA, Chiu SH.
    Drug Metab Dispos; 1997 Aug 10; 25(8):940-52. PubMed ID: 9280402
    [Abstract] [Full Text] [Related]

  • 8. Metabolism of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): identification of an unusual N-acetylglucosamine conjugate in the cynomolgus monkey.
    Johnson BM, Kamath AV, Leet JE, Liu X, Bhide RS, Tejwani RW, Zhang Y, Qian L, Wei DD, Lombardo LJ, Shu YZ.
    Drug Metab Dispos; 2008 Dec 10; 36(12):2475-83. PubMed ID: 18787055
    [Abstract] [Full Text] [Related]

  • 9. Characterization of metabolites of xylazine produced in vivo and in vitro by LC/MS/MS and by GC/MS.
    Mutlib AE, Chui YC, Young LM, Abbott FS.
    Drug Metab Dispos; 1992 Dec 10; 20(6):840-8. PubMed ID: 1362936
    [Abstract] [Full Text] [Related]

  • 10. Characterization of the novel benzisothiazole ring-cleaved products of the antipsychotic drug ziprasidone.
    Prakash C, Kamel A, Cui D.
    Drug Metab Dispos; 1997 Jul 10; 25(7):897-901. PubMed ID: 9224786
    [Abstract] [Full Text] [Related]

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  • 12. Metabolism of a 14C/3H-labeled GABAA receptor partial agonist in rat, dog and human liver microsomes: evaluation of a dual-radiolabel strategy.
    Shaffer CL, Langer CS.
    J Pharm Biomed Anal; 2007 Mar 12; 43(4):1195-205. PubMed ID: 17150324
    [Abstract] [Full Text] [Related]

  • 13. Biotransformation of 2,3,3,3-tetrafluoropropene (HFO-1234yf).
    Schuster P, Bertermann R, Snow TA, Han X, Rusch GM, Jepson GW, Dekant W.
    Toxicol Appl Pharmacol; 2008 Dec 01; 233(2):323-32. PubMed ID: 18817801
    [Abstract] [Full Text] [Related]

  • 14. Thiophene sulfoxides as reactive metabolites: formation upon microsomal oxidation of a 3-aroylthiophene and fate in the presence of nucleophiles in vitro and in vivo.
    Valadon P, Dansette PM, Girault JP, Amar C, Mansuy D.
    Chem Res Toxicol; 1996 Dec 01; 9(8):1403-13. PubMed ID: 8951246
    [Abstract] [Full Text] [Related]

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  • 16. Liquid chromatography/nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry identification of novel metabolites of the multidrug resistance modulator LY335979 in rat bile and human liver microsomal incubations.
    Ehlhardt WJ, Woodland JM, Baughman TM, Vandenbranden M, Wrighton SA, Kroin JS, Norman BH, Maple SR.
    Drug Metab Dispos; 1998 Jan 01; 26(1):42-51. PubMed ID: 9443851
    [Abstract] [Full Text] [Related]

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  • 18. Characterization of metabolic profile of mosapride citrate in rat and identification of two new metabolites: Mosapride N-oxide and morpholine ring-opened mosapride by UPLC-ESI-MS/MS.
    Sun X, Niu L, Li X, Lu X, Li F.
    J Pharm Biomed Anal; 2009 Aug 15; 50(1):27-34. PubMed ID: 19362796
    [Abstract] [Full Text] [Related]

  • 19. Biotransformation of 3-amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a novel 5-hydroxytryptamine (5-HT)1A agonist/5-HT3 antagonist, in human hepatic cytochrome P450 enzymes.
    Minato K, Suzuki R, Asagarasu A, Matsui T, Sato M.
    Drug Metab Dispos; 2008 May 15; 36(5):831-40. PubMed ID: 18238859
    [Abstract] [Full Text] [Related]

  • 20. In vivo and in vitro metabolism of lefucoxib in rats.
    Bi X, Meng Z, Chen H, Zhu X, Dou G.
    J Pharm Biomed Anal; 2008 Sep 10; 48(1):134-9. PubMed ID: 18538525
    [Abstract] [Full Text] [Related]

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