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837 related items for PubMed ID: 8895571

  • 1. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.
    Brunn GJ, Williams J, Sabers C, Wiederrecht G, Lawrence JC, Abraham RT.
    EMBO J; 1996 Oct 01; 15(19):5256-67. PubMed ID: 8895571
    [Abstract] [Full Text] [Related]

  • 2. Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin.
    Brunn GJ, Hudson CC, Sekulić A, Williams JM, Hosoi H, Houghton PJ, Lawrence JC, Abraham RT.
    Science; 1997 Jul 04; 277(5322):99-101. PubMed ID: 9204908
    [Abstract] [Full Text] [Related]

  • 3. Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
    Bishop JD, Nien WL, Dauphinee SM, Too CK.
    J Endocrinol; 2006 Aug 04; 190(2):307-12. PubMed ID: 16899564
    [Abstract] [Full Text] [Related]

  • 4. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T, Nishioka C, Bandobashi K, Yang Y, Kuwayama Y, Adachi Y, Takeuchi T, Koeffler HP, Taguchi H.
    Leuk Res; 2007 May 04; 31(5):673-82. PubMed ID: 17007924
    [Abstract] [Full Text] [Related]

  • 5. IL-2 induces beta2-integrin adhesion via a wortmannin/LY294002-sensitive, rapamycin-resistant pathway. Phosphorylation of a 125-kilodalton protein correlates with induction of adhesion, but not mitogenesis.
    Nielsen M, Svejgaard A, Skov S, Dobson P, Bendtzen K, Geisler C, Odum N.
    J Immunol; 1996 Dec 15; 157(12):5350-8. PubMed ID: 8955182
    [Abstract] [Full Text] [Related]

  • 6. Activation of phosphatidylinositol 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects of rapamycin, Ly294002, and wortmannin on nitric oxide production.
    Salh B, Wagey R, Marotta A, Tao JS, Pelech S.
    J Immunol; 1998 Dec 15; 161(12):6947-54. PubMed ID: 9862729
    [Abstract] [Full Text] [Related]

  • 7. ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells.
    Hafizi S, Wang X, Chester AH, Yacoub MH, Proud CG.
    Am J Physiol Heart Circ Physiol; 2004 Sep 15; 287(3):H1232-8. PubMed ID: 15317677
    [Abstract] [Full Text] [Related]

  • 8. Regulation of protein synthesis by cholecystokinin in rat pancreatic acini involves PHAS-I and the p70 S6 kinase pathway.
    Bragado MJ, Groblewski GE, Williams JA.
    Gastroenterology; 1998 Sep 15; 115(3):733-42. PubMed ID: 9721171
    [Abstract] [Full Text] [Related]

  • 9. 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway.
    Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N.
    Genes Dev; 1998 Feb 15; 12(4):502-13. PubMed ID: 9472019
    [Abstract] [Full Text] [Related]

  • 10. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.
    Cancer Res; 2000 Jul 01; 60(13):3504-13. PubMed ID: 10910062
    [Abstract] [Full Text] [Related]

  • 11. Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts.
    Takuwa N, Fukui Y, Takuwa Y.
    Mol Cell Biol; 1999 Feb 01; 19(2):1346-58. PubMed ID: 9891068
    [Abstract] [Full Text] [Related]

  • 12. Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathway.
    Li W, Sumpio BE.
    Am J Physiol Heart Circ Physiol; 2005 Apr 01; 288(4):H1591-7. PubMed ID: 15591103
    [Abstract] [Full Text] [Related]

  • 13. Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70 S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine.
    Crawley JB, Williams LM, Mander T, Brennan FM, Foxwell BM.
    J Biol Chem; 1996 Jul 05; 271(27):16357-62. PubMed ID: 8663063
    [Abstract] [Full Text] [Related]

  • 14. Cellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein.
    Fraser CS, Pain VM, Morley SJ.
    Biochem J; 1999 Sep 15; 342 Pt 3(Pt 3):519-26. PubMed ID: 10477262
    [Abstract] [Full Text] [Related]

  • 15. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism.
    Hara K, Yonezawa K, Weng QP, Kozlowski MT, Belham C, Avruch J.
    J Biol Chem; 1998 Jun 05; 273(23):14484-94. PubMed ID: 9603962
    [Abstract] [Full Text] [Related]

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  • 17. Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.
    Pham PT, Heydrick SJ, Fox HL, Kimball SR, Jefferson LS, Lynch CJ.
    J Cell Biochem; 2000 Sep 07; 79(3):427-41. PubMed ID: 10972980
    [Abstract] [Full Text] [Related]

  • 18. Rapamycin resistance in ataxia-telangiectasia.
    Beamish H, Williams R, Chen P, Khanna KK, Hobson K, Watters D, Shiloh Y, Lavin M.
    Oncogene; 1996 Sep 05; 13(5):963-70. PubMed ID: 8806686
    [Abstract] [Full Text] [Related]

  • 19. Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.
    Hou L, Klann E.
    J Neurosci; 2004 Jul 14; 24(28):6352-61. PubMed ID: 15254091
    [Abstract] [Full Text] [Related]

  • 20. Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway.
    Scott PH, Brunn GJ, Kohn AD, Roth RA, Lawrence JC.
    Proc Natl Acad Sci U S A; 1998 Jun 23; 95(13):7772-7. PubMed ID: 9636226
    [Abstract] [Full Text] [Related]

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