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117 related items for PubMed ID: 8901913

  • 1. A physiological toxicokinetic model for 1,3-butadiene in rodents and man: blood concentrations of 1,3-butadiene, its metabolically formed epoxides, and of haemoglobin adducts--relevance of glutathione depletion.
    Csanády GA, Kreuzer PE, Baur C, Filser JG.
    Toxicology; 1996 Oct 28; 113(1-3):300-5. PubMed ID: 8901913
    [Abstract] [Full Text] [Related]

  • 2. A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation.
    Johanson G, Filser JG.
    Arch Toxicol; 1993 Oct 28; 67(3):151-63. PubMed ID: 8494494
    [Abstract] [Full Text] [Related]

  • 3. Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation.
    Himmelstein MW, Turner MJ, Asgharian B, Bond JA.
    Carcinogenesis; 1994 Aug 28; 15(8):1479-86. PubMed ID: 8055623
    [Abstract] [Full Text] [Related]

  • 4. Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice.
    Csanády GA, Guengerich FP, Bond JA.
    Carcinogenesis; 1992 Jul 28; 13(7):1143-53. PubMed ID: 1638680
    [Abstract] [Full Text] [Related]

  • 5. Physiologically based pharmacokinetic modeling of 1,3-butadiene, 1,2-epoxy-3-butene, and 1,2:3,4-diepoxybutane toxicokinetics in mice and rats.
    Sweeney LM, Schlosser PM, Medinsky MA, Bond JA.
    Carcinogenesis; 1997 Apr 28; 18(4):611-25. PubMed ID: 9111190
    [Abstract] [Full Text] [Related]

  • 6. PBPK model for butadiene metabolism to epoxides: quantitative species differences in metabolism.
    Johanson G, Filser JG.
    Toxicology; 1996 Oct 28; 113(1-3):40-7. PubMed ID: 8901881
    [Abstract] [Full Text] [Related]

  • 7. Metabolism of 1,3-butadiene: inhalation pharmacokinetics and tissue dosimetry of butadiene epoxides in rats and mice.
    Himmelstein MW, Turner MJ, Asgharian B, Bond JA.
    Toxicology; 1996 Oct 28; 113(1-3):306-9. PubMed ID: 8901914
    [Abstract] [Full Text] [Related]

  • 8. Glutathione conjugation of 1,2:3,4- diepoxybutane in human liver and rat and mouse liver and lung in vitro.
    Boogaard PJ, Sumner SC, Bond JA.
    Toxicol Appl Pharmacol; 1996 Feb 28; 136(2):307-16. PubMed ID: 8619238
    [Abstract] [Full Text] [Related]

  • 9. Research strategy for assessing target tissue dosimetry of 1,3-butadiene in laboratory animals and humans.
    Bond JA, Csanády GA, Leavens T, Medinsky MA.
    IARC Sci Publ; 1993 Feb 28; (127):45-55. PubMed ID: 8070886
    [Abstract] [Full Text] [Related]

  • 10. Effects of the structure of a toxicokinetic model of butadiene inhalation exposure on computed production of carcinogenic intermediates.
    Kohn MC, Melnick RL.
    Toxicology; 1996 Oct 28; 113(1-3):31-9. PubMed ID: 8901880
    [Abstract] [Full Text] [Related]

  • 11. High concentrations of butadiene epoxides in livers and lungs of mice compared to rats exposed to 1,3-butadiene.
    Himmelstein MW, Asgharian B, Bond JA.
    Toxicol Appl Pharmacol; 1995 Jun 28; 132(2):281-8. PubMed ID: 7785055
    [Abstract] [Full Text] [Related]

  • 12. Stereochemical aspects of the conjugation of epoxide metabolites of butadiene with glutathione in rat liver cytosol and freshly isolated rat hepatocytes.
    Nieusma JL, Claffey DJ, Ruth JA, Ross D.
    Toxicol Sci; 1998 Jun 28; 43(2):102-9. PubMed ID: 9710951
    [Abstract] [Full Text] [Related]

  • 13. Disposition of butadiene epoxides in Sprague-Dawley rats.
    Valentine JL, Boogaard PJ, Sweeney LM, Turner MJ, Bond JA, Medinsky MA.
    Chem Biol Interact; 1997 May 02; 104(2-3):103-15. PubMed ID: 9212778
    [Abstract] [Full Text] [Related]

  • 14. Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes.
    Seaton MJ, Follansbee MH, Bond JA.
    Carcinogenesis; 1995 Oct 02; 16(10):2287-93. PubMed ID: 7586124
    [Abstract] [Full Text] [Related]

  • 15. In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.
    Motwani HV, Törnqvist M.
    Toxicol Appl Pharmacol; 2014 Dec 15; 281(3):276-84. PubMed ID: 25448046
    [Abstract] [Full Text] [Related]

  • 16. Metabolism of butadiene by mice, rats, and humans: a comparison of physiologically based toxicokinetic model predictions and experimental data.
    Bond JA, Himmelstein MW, Seaton M, Boogaard P, Medinsky MA.
    Toxicology; 1996 Oct 28; 113(1-3):48-54. PubMed ID: 8901882
    [Abstract] [Full Text] [Related]

  • 17. DNA adducts in rats and mice following exposure to [4-14C]-1,2-epoxy-3-butene and to [2,3-14C]-1,3-butadiene.
    Boogaard PJ, de Kloe KP, Booth ED, Watson WP.
    Chem Biol Interact; 2004 Jun 30; 148(1-2):69-92. PubMed ID: 15223358
    [Abstract] [Full Text] [Related]

  • 18. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
    Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF, Health Review Committee.
    Res Rep Health Eff Inst; 2009 Aug 30; (144):3-79. PubMed ID: 20017413
    [Abstract] [Full Text] [Related]

  • 19. Haemoglobin adducts of epoxybutanediol from exposure to 1,3-butadiene or butadiene epoxides.
    Pérez HL, Lähdetie J, Landin H, Kilpeläinen I, Koivisto P, Peltonen K, Osterman-Golkar S.
    Chem Biol Interact; 1997 Aug 01; 105(3):181-98. PubMed ID: 9291996
    [Abstract] [Full Text] [Related]

  • 20. 1,2:3,4-Diepoxybutane in blood of male B6C3F1 mice and male Sprague-Dawley rats exposed to 1,3-butadiene.
    Csanády GA, Steinhoff R, Riester MB, Semder B, Pütz C, Li Q, Richter N, Kessler W, Klein D, Filser JG.
    Toxicol Lett; 2011 Dec 15; 207(3):286-90. PubMed ID: 21983653
    [Abstract] [Full Text] [Related]

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