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162 related items for PubMed ID: 8903321

  • 1. The mutation in the mitochondrial aldehyde dehydrogenase (ALDH2) gene responsible for alcohol-induced flushing increases turnover of the enzyme tetramers in a dominant fashion.
    Xiao Q, Weiner H, Crabb DW.
    J Clin Invest; 1996 Nov 01; 98(9):2027-32. PubMed ID: 8903321
    [Abstract] [Full Text] [Related]

  • 2. Studies on the enzymology of aldehyde dehydrogenase-2 in genetically modified HeLa cells.
    Crabb D, Xiao Q.
    Alcohol Clin Exp Res; 1998 Jun 01; 22(4):780-1. PubMed ID: 9660300
    [Abstract] [Full Text] [Related]

  • 3. The aldehyde dehydrogenase ALDH2*2 allele exhibits dominance over ALDH2*1 in transduced HeLa cells.
    Xiao Q, Weiner H, Johnston T, Crabb DW.
    J Clin Invest; 1995 Nov 01; 96(5):2180-6. PubMed ID: 7593603
    [Abstract] [Full Text] [Related]

  • 4. Dominance of the inactive Asian variant over activity and protein contents of mitochondrial aldehyde dehydrogenase 2 in human liver.
    Lai CL, Yao CT, Chau GY, Yang LF, Kuo TY, Chiang CP, Yin SJ.
    Alcohol Clin Exp Res; 2014 Jan 01; 38(1):44-50. PubMed ID: 23909789
    [Abstract] [Full Text] [Related]

  • 5. Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant.
    Crabb DW, Edenberg HJ, Bosron WF, Li TK.
    J Clin Invest; 1989 Jan 01; 83(1):314-6. PubMed ID: 2562960
    [Abstract] [Full Text] [Related]

  • 6. Dominance of the mutant ALDH2(2) allele in the expression of human stomach aldehyde dehydrogenase-2 activity.
    Chao YC, Liou SR, Tsai SF, Yin SJ.
    Proc Natl Sci Counc Repub China B; 1993 Jul 01; 17(3):98-102. PubMed ID: 8290656
    [Abstract] [Full Text] [Related]

  • 7. ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis.
    Jin S, Chen J, Chen L, Histen G, Lin Z, Gross S, Hixon J, Chen Y, Kung C, Chen Y, Fu Y, Lu Y, Lin H, Cai X, Yang H, Cairns RA, Dorsch M, Su SM, Biller S, Mak TW, Cang Y.
    Proc Natl Acad Sci U S A; 2015 Jul 21; 112(29):9088-93. PubMed ID: 26150517
    [Abstract] [Full Text] [Related]

  • 8. Eliciting the low-activity aldehyde dehydrogenase Asian phenotype by an antisense mechanism results in an aversion to ethanol.
    Garver E, Tu Gc, Cao QN, Aini M, Zhou F, Israel Y.
    J Exp Med; 2001 Sep 03; 194(5):571-80. PubMed ID: 11535626
    [Abstract] [Full Text] [Related]

  • 9. Genetic polymorphism of cytochrome P-4502E1 and mitochondrial aldehyde dehydrogenase in a Korean population.
    Lee KH, Kwak BY, Kim JH, Yoo SK, Yum SK, Jeong HS.
    Alcohol Clin Exp Res; 1997 Sep 03; 21(6):953-6. PubMed ID: 9309300
    [Abstract] [Full Text] [Related]

  • 10. Polymorphism of alcohol-metabolizing genes affects drinking behavior and alcoholic liver disease in Japanese men.
    Tanaka F, Shiratori Y, Yokosuka O, Imazeki F, Tsukada Y, Omata M.
    Alcohol Clin Exp Res; 1997 Jun 03; 21(4):596-601. PubMed ID: 9194910
    [Abstract] [Full Text] [Related]

  • 11. Mutations in mitochondrial aldehyde dehydrogenase (ALDH2) change cofactor affinity and segregate with voluntary alcohol consumption in rats.
    Sapag A, Tampier L, Valle-Prieto A, Quintanilla ME, Moncada C, Israel Y.
    Pharmacogenetics; 2003 Aug 03; 13(8):509-15. PubMed ID: 12893989
    [Abstract] [Full Text] [Related]

  • 12. Alcohol and aldehyde dehydrogenase gene polymorphisms influence susceptibility to esophageal cancer in Japanese alcoholics.
    Yokoyama A, Muramatsu T, Omori T, Matsushita S, Yoshimizu H, Higuchi S, Yokoyama T, Maruyama K, Ishii H.
    Alcohol Clin Exp Res; 1999 Nov 03; 23(11):1705-10. PubMed ID: 10591585
    [Abstract] [Full Text] [Related]

  • 13. RNA interference against aldehyde dehydrogenase-2: development of tools for alcohol research.
    Cortínez G, Sapag A, Israel Y.
    Alcohol; 2009 Mar 03; 43(2):97-104. PubMed ID: 19251111
    [Abstract] [Full Text] [Related]

  • 14. Genetic polymorphism of alcohol and aldehyde dehydrogenase and the effects on alcohol metabolism.
    Yamamoto K, Ueno Y, Mizoi Y, Tatsuno Y.
    Arukoru Kenkyuto Yakubutsu Ison; 1993 Feb 03; 28(1):13-25. PubMed ID: 8512495
    [Abstract] [Full Text] [Related]

  • 15. Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant.
    Perez-Miller S, Younus H, Vanam R, Chen CH, Mochly-Rosen D, Hurley TD.
    Nat Struct Mol Biol; 2010 Feb 03; 17(2):159-64. PubMed ID: 20062057
    [Abstract] [Full Text] [Related]

  • 16. Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion.
    Steinmetz CG, Xie P, Weiner H, Hurley TD.
    Structure; 1997 May 15; 5(5):701-11. PubMed ID: 9195888
    [Abstract] [Full Text] [Related]

  • 17. Monoamine metabolism and behavioral responses to ethanol in mitochondrial aldehyde dehydrogenase knockout mice.
    Fernandez E, Koek W, Ran Q, Gerhardt GA, France CP, Strong R.
    Alcohol Clin Exp Res; 2006 Oct 15; 30(10):1650-8. PubMed ID: 17010132
    [Abstract] [Full Text] [Related]

  • 18. Chaperonin GroESL mediates the protein folding of human liver mitochondrial aldehyde dehydrogenase in Escherichia coli.
    Lee KH, Kim HS, Jeong HS, Lee YS.
    Biochem Biophys Res Commun; 2002 Oct 25; 298(2):216-24. PubMed ID: 12387818
    [Abstract] [Full Text] [Related]

  • 19. Formation of acetaldehyde-derived DNA adducts due to alcohol exposure.
    Yu HS, Oyama T, Isse T, Kitagawa K, Pham TT, Tanaka M, Kawamoto T.
    Chem Biol Interact; 2010 Dec 05; 188(3):367-75. PubMed ID: 20813101
    [Abstract] [Full Text] [Related]

  • 20. Ethanol and acetaldehyde metabolism in chinese with different aldehyde dehydrogenase-2 genotypes.
    Luu SU, Wang MF, Lin DL, Kao MH, Chen ML, Chiang CH, Pai L, Yin SJ.
    Proc Natl Sci Counc Repub China B; 1995 Jul 05; 19(3):129-36. PubMed ID: 7480358
    [Abstract] [Full Text] [Related]

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