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Journal Abstract Search

248 related items for PubMed ID: 8906793

  • 1. Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
    Weidner KM, Di Cesare S, Sachs M, Brinkmann V, Behrens J, Birchmeier W.
    Nature; 1996 Nov 14; 384(6605):173-6. PubMed ID: 8906793
    [Abstract] [Full Text] [Related]

  • 2. Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.
    Bardelli A, Longati P, Gramaglia D, Stella MC, Comoglio PM.
    Oncogene; 1997 Dec 18; 15(25):3103-11. PubMed ID: 9444958
    [Abstract] [Full Text] [Related]

  • 3. The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.
    Lewitzky M, Kardinal C, Gehring NH, Schmidt EK, Konkol B, Eulitz M, Birchmeier W, Schaeper U, Feller SM.
    Oncogene; 2001 Mar 01; 20(9):1052-62. PubMed ID: 11314042
    [Abstract] [Full Text] [Related]

  • 4. Gab2 requires membrane targeting and the Met binding motif to promote lamellipodia, cell scatter, and epithelial morphogenesis downstream from the Met receptor.
    Frigault MM, Naujokas MA, Park M.
    J Cell Physiol; 2008 Mar 01; 214(3):694-705. PubMed ID: 17894413
    [Abstract] [Full Text] [Related]

  • 5. The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R.
    Jones N, Dumont DJ.
    Oncogene; 1998 Sep 03; 17(9):1097-108. PubMed ID: 9764820
    [Abstract] [Full Text] [Related]

  • 6. MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
    Higuchi T, Orita T, Katsuya K, Yamasaki Y, Akiyama K, Li H, Yamamoto T, Saito Y, Nakamura M.
    Mol Cell Biol; 2004 Sep 03; 24(17):7456-68. PubMed ID: 15314156
    [Abstract] [Full Text] [Related]

  • 7. Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases.
    Lock LS, Royal I, Naujokas MA, Park M.
    J Biol Chem; 2000 Oct 06; 275(40):31536-45. PubMed ID: 10913131
    [Abstract] [Full Text] [Related]

  • 8. Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain.
    Lock LS, Frigault MM, Saucier C, Park M.
    J Biol Chem; 2003 Aug 08; 278(32):30083-90. PubMed ID: 12766170
    [Abstract] [Full Text] [Related]

  • 9. Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
    Schaeper U, Gehring NH, Fuchs KP, Sachs M, Kempkes B, Birchmeier W.
    J Cell Biol; 2000 Jun 26; 149(7):1419-32. PubMed ID: 10871282
    [Abstract] [Full Text] [Related]

  • 10. Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis.
    Saucier C, Papavasiliou V, Palazzo A, Naujokas MA, Kremer R, Park M.
    Oncogene; 2002 Mar 14; 21(12):1800-11. PubMed ID: 11896612
    [Abstract] [Full Text] [Related]

  • 11. Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis.
    Gual P, Giordano S, Williams TA, Rocchi S, Van Obberghen E, Comoglio PM.
    Oncogene; 2000 Mar 16; 19(12):1509-18. PubMed ID: 10734310
    [Abstract] [Full Text] [Related]

  • 12. Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis.
    Lock LS, Maroun CR, Naujokas MA, Park M.
    Mol Biol Cell; 2002 Jun 16; 13(6):2132-46. PubMed ID: 12058075
    [Abstract] [Full Text] [Related]

  • 13. The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase.
    Maroun CR, Holgado-Madruga M, Royal I, Naujokas MA, Fournier TM, Wong AJ, Park M.
    Mol Cell Biol; 1999 Mar 16; 19(3):1784-99. PubMed ID: 10022866
    [Abstract] [Full Text] [Related]

  • 14. Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes.
    Nakaoka Y, Nishida K, Fujio Y, Izumi M, Terai K, Oshima Y, Sugiyama S, Matsuda S, Koyasu S, Yamauchi-Takihara K, Hirano T, Kawase I, Hirota H.
    Circ Res; 2003 Aug 08; 93(3):221-9. PubMed ID: 12855672
    [Abstract] [Full Text] [Related]

  • 15. Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells.
    Holland SJ, Gale NW, Gish GD, Roth RA, Songyang Z, Cantley LC, Henkemeyer M, Yancopoulos GD, Pawson T.
    EMBO J; 1997 Jul 01; 16(13):3877-88. PubMed ID: 9233798
    [Abstract] [Full Text] [Related]

  • 16. Unique phosphorylation mechanism of Gab1 using PI 3-kinase as an adaptor protein.
    Onishi-Haraikawa Y, Funaki M, Gotoh N, Shibuya M, Inukai K, Katagiri H, Fukushima Y, Anai M, Ogihara T, Sakoda H, Ono H, Kikuchi M, Oka Y, Asano T.
    Biochem Biophys Res Commun; 2001 Oct 26; 288(2):476-82. PubMed ID: 11606067
    [Abstract] [Full Text] [Related]

  • 17. Membrane targeting of Grb2-associated binder-1 (Gab1) scaffolding protein through Src myristoylation sequence substitutes for Gab1 pleckstrin homology domain and switches an epidermal growth factor response to an invasive morphogenic program.
    Maroun CR, Naujokas MA, Park M.
    Mol Biol Cell; 2003 Apr 26; 14(4):1691-708. PubMed ID: 12686619
    [Abstract] [Full Text] [Related]

  • 18. Redundant roles for Met docking site tyrosines and the Gab1 pleckstrin homology domain in InlB-mediated entry of Listeria monocytogenes.
    Basar T, Shen Y, Ireton K.
    Infect Immun; 2005 Apr 26; 73(4):2061-74. PubMed ID: 15784547
    [Abstract] [Full Text] [Related]

  • 19. Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.
    Nguyen L, Holgado-Madruga M, Maroun C, Fixman ED, Kamikura D, Fournier T, Charest A, Tremblay ML, Wong AJ, Park M.
    J Biol Chem; 1997 Aug 15; 272(33):20811-9. PubMed ID: 9252406
    [Abstract] [Full Text] [Related]

  • 20. Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
    Schaeper U, Vogel R, Chmielowiec J, Huelsken J, Rosario M, Birchmeier W.
    Proc Natl Acad Sci U S A; 2007 Sep 25; 104(39):15376-81. PubMed ID: 17881575
    [Abstract] [Full Text] [Related]

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