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151 related items for PubMed ID: 8910319

  • 21. Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cells.
    Virtanen SS, Sandholm J, Yegutkin G, Kalervo Väänänen H, Härkönen PL.
    Cell Biol Int; 2010 Aug; 34(8):815-26. PubMed ID: 20446922
    [Abstract] [Full Text] [Related]

  • 22. Integrin-dependent leukocyte adhesion involves geranylgeranylated protein(s).
    Liu L, Moesner P, Kovach NL, Bailey R, Hamilton AD, Sebti SM, Harlan JM.
    J Biol Chem; 1999 Nov 19; 274(47):33334-40. PubMed ID: 10559211
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  • 23. Insulin stimulates mitogen-activated protein kinase by a Ras-independent pathway in 3T3-L1 adipocytes.
    Carel K, Kummer JL, Schubert C, Leitner W, Heidenreich KA, Draznin B.
    J Biol Chem; 1996 Nov 29; 271(48):30625-30. PubMed ID: 8940037
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  • 24. Inhibition of platelet-derived growth factor and epidermal growth factor receptor signaling events after treatment of cells with specific synthetic inhibitors of tyrosine kinase phosphorylation.
    Lipson KE, Pang L, Huber LJ, Chen H, Tsai JM, Hirth P, Gazit A, Levitzki A, McMahon G.
    J Pharmacol Exp Ther; 1998 May 29; 285(2):844-52. PubMed ID: 9580635
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  • 25. STAT activation by the PDGF receptor requires juxtamembrane phosphorylation sites but not Src tyrosine kinase activation.
    Sachsenmaier C, Sadowski HB, Cooper JA.
    Oncogene; 1999 Jun 17; 18(24):3583-92. PubMed ID: 10380880
    [Abstract] [Full Text] [Related]

  • 26. Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: combination therapy with the cytotoxic agents cisplatin, Taxol, and gemcitabine.
    Sun J, Blaskovich MA, Knowles D, Qian Y, Ohkanda J, Bailey RD, Hamilton AD, Sebti SM.
    Cancer Res; 1999 Oct 01; 59(19):4919-26. PubMed ID: 10519405
    [Abstract] [Full Text] [Related]

  • 27. Platelet-derived growth factor stimulates sodium-dependent Pi transport in osteoblastic cells via phospholipase Cgamma and phosphatidylinositol 3' -kinase.
    Zhen X, Bonjour JP, Caverzasio J.
    J Bone Miner Res; 1997 Jan 01; 12(1):36-44. PubMed ID: 9240723
    [Abstract] [Full Text] [Related]

  • 28. Insulin stimulates the phosphorylation and activity of farnesyltransferase via the Ras-mitogen-activated protein kinase pathway.
    Goalstone M, Carel K, Leitner JW, Draznin B.
    Endocrinology; 1997 Dec 01; 138(12):5119-24. PubMed ID: 9389491
    [Abstract] [Full Text] [Related]

  • 29. [Inhibitors of isoprenylation of ras p21].
    Yoshimatsu K.
    Gan To Kagaku Ryoho; 1997 Sep 01; 24(11):1495-502. PubMed ID: 9309147
    [Abstract] [Full Text] [Related]

  • 30. Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins.
    Yokote K, Hellman U, Ekman S, Saito Y, Rönnstrand L, Saito Y, Heldin CH, Mori S.
    Oncogene; 1998 Mar 12; 16(10):1229-39. PubMed ID: 9546424
    [Abstract] [Full Text] [Related]

  • 31. Requirement for phosphatidylinositol 3'-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin.
    Rankin S, Hooshmand-Rad R, Claesson-Welsh L, Rozengurt E.
    J Biol Chem; 1996 Mar 29; 271(13):7829-34. PubMed ID: 8631827
    [Abstract] [Full Text] [Related]

  • 32. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
    Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE.
    Cancer Res; 2001 Dec 15; 61(24):8758-68. PubMed ID: 11751396
    [Abstract] [Full Text] [Related]

  • 33. Lovastatin inhibits the stimulation of mitogen-activated protein kinase by insulin in HIRcB fibroblasts.
    Xu XQ, McGuire TF, Blaskovich MA, Sebti SM, Romero G.
    Arch Biochem Biophys; 1996 Feb 15; 326(2):233-7. PubMed ID: 8611028
    [Abstract] [Full Text] [Related]

  • 34. The catalytic subunit of phosphatidylinositol 3-kinase is a substrate for the activated platelet-derived growth factor receptor, but not for middle-T antigen-pp60c-src complexes.
    Roche S, Dhand R, Waterfield MD, Courtneidge SA.
    Biochem J; 1994 Aug 01; 301 ( Pt 3)(Pt 3):703-11. PubMed ID: 7519847
    [Abstract] [Full Text] [Related]

  • 35. Selective inhibition of platelet-derived growth factor (PDGF) receptor autophosphorylation and PDGF-mediated cellular events by a quinoline derivative.
    Yagi M, Kato S, Kobayashi Y, Kubo K, Oyama S, Shimizu T, Nishitoba T, Isoe T, Nakamura K, Ohashi H, Kobayashi N, Iinuma N, Osawa T, Onose R, Osada H.
    Exp Cell Res; 1997 Aug 01; 234(2):285-92. PubMed ID: 9260896
    [Abstract] [Full Text] [Related]

  • 36. Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro.
    James GL, Goldstein JL, Brown MS.
    J Biol Chem; 1995 Mar 17; 270(11):6221-6. PubMed ID: 7890759
    [Abstract] [Full Text] [Related]

  • 37. SHP-2 binds to Tyr763 and Tyr1009 in the PDGF beta-receptor and mediates PDGF-induced activation of the Ras/MAP kinase pathway and chemotaxis.
    Rönnstrand L, Arvidsson AK, Kallin A, Rorsman C, Hellman U, Engström U, Wernstedt C, Heldin CH.
    Oncogene; 1999 Jun 24; 18(25):3696-702. PubMed ID: 10391677
    [Abstract] [Full Text] [Related]

  • 38. A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling.
    Waltenberger J, Uecker A, Kroll J, Frank H, Mayr U, Bjorge JD, Fujita D, Gazit A, Hombach V, Levitzki A, Böhmer FD.
    Circ Res; 1999 Jul 09; 85(1):12-22. PubMed ID: 10400906
    [Abstract] [Full Text] [Related]

  • 39. Effect of insulin on farnesyltransferase. Specificity of insulin action and potentiation of nuclear effects of insulin-like growth factor-1, epidermal growth factor, and platelet-derived growth factor.
    Goalstone ML, Leitner JW, Wall K, Dolgonos L, Rother KI, Accili D, Draznin B.
    J Biol Chem; 1998 Sep 11; 273(37):23892-6. PubMed ID: 9727002
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  • 40. Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor.
    Kusama T, Mukai M, Tatsuta M, Matsumoto Y, Nakamura H, Inoue M.
    Clin Exp Metastasis; 2003 Sep 11; 20(6):561-7. PubMed ID: 14598891
    [Abstract] [Full Text] [Related]

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