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Journal Abstract Search

284 related items for PubMed ID: 8911874

  • 1. Phenotype and genotype analysis of debrisoquine hydroxylase (CYP2D6) in a black Zimbabwean population. Reduced enzyme activity and evaluation of metabolic correlation of CYP2D6 probe drugs.
    Masimirembwa C, Hasler J, Bertilssons L, Johansson I, Ekberg O, Ingelman-Sundberg M.
    Eur J Clin Pharmacol; 1996; 51(2):117-22. PubMed ID: 8911874
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  • 2. Metabolic ratios of four probes of CYP2D6 in Turkish subjects: a cross-over study.
    Bozkurt A, Basçi NE, Işimer A, Sayal A, Kayaalp SO.
    Eur J Drug Metab Pharmacokinet; 1996; 21(4):309-14. PubMed ID: 9074895
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  • 3. A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: association with diminished debrisoquine hydroxylase activity.
    Masimirembwa C, Persson I, Bertilsson L, Hasler J, Ingelman-Sundberg M.
    Br J Clin Pharmacol; 1996 Dec; 42(6):713-9. PubMed ID: 8971426
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  • 4. Decreased capacity for debrisoquine metabolism among black Tanzanians: analyses of the CYP2D6 genotype and phenotype.
    Wennerholm A, Johansson I, Massele AY, Lande M, Alm C, Aden-Abdi Y, Dahl ML, Ingelman-Sundberg M, Bertilsson L, Gustafsson LL.
    Pharmacogenetics; 1999 Dec; 9(6):707-14. PubMed ID: 10634133
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  • 5. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.
    Sachse C, Brockmöller J, Bauer S, Roots I.
    Am J Hum Genet; 1997 Feb; 60(2):284-95. PubMed ID: 9012401
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  • 8. Genetic polymorphism of debrisoquine (CYP2D6) and proguanil (CYP2C19) in South Pacific Polynesian populations.
    Wanwimolruk S, Bhawan S, Coville PF, Chalcroft SC.
    Eur J Clin Pharmacol; 1998 Jul; 54(5):431-5. PubMed ID: 9754989
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  • 9. 3,4-Dehydrodebrisoquine, a novel debrisoquine metabolite formed from 4-hydroxydebrisoquine that affects the CYP2D6 metabolic ratio.
    Zhen Y, Slanar O, Krausz KW, Chen C, Slavík J, McPhail KL, Zabriskie TM, Perlík F, Gonzalez FJ, Idle JR.
    Drug Metab Dispos; 2006 Sep; 34(9):1563-74. PubMed ID: 16782768
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  • 12. Determination of debrisoquine and 4-hydroxydebrisoquine by high-performance liquid chromatography: application to the evaluation of CYP2D6 genotype and debrisoquine metabolic ratio relationship.
    Dorado P, Berecz R, Cáceres MC, González I, Cobaleda J, Llerena A.
    Clin Chem Lab Med; 2005 Sep; 43(3):275-9. PubMed ID: 15843230
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  • 15. Debrisoquine and mephenytoin oxidation in Sinhalese: a population study.
    Weerasuriya K, Jayakody RL, Smith CA, Wolf CR, Tucker GT, Lennard MS.
    Br J Clin Pharmacol; 1994 Nov; 38(5):466-70. PubMed ID: 7893590
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  • 16. CYP2D6 polymorphism in systemic lupus erythematosus patients.
    Kortunay S, Bozkurt A, Bathum L, Basci NE, Calgüneri M, Brøsen K, Kayaalp SO.
    Eur J Clin Pharmacol; 1999 Mar; 55(1):21-5. PubMed ID: 10206080
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  • 17. The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity.
    Wennerholm A, Dandara C, Sayi J, Svensson JO, Abdi YA, Ingelman-Sundberg M, Bertilsson L, Hasler J, Gustafsson LL.
    Clin Pharmacol Ther; 2002 Jan; 71(1):77-88. PubMed ID: 11823760
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  • 18. Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes.
    Daly AK, Armstrong M, Monkman SC, Idle ME, Idle JR.
    Pharmacogenetics; 1991 Oct; 1(1):33-41. PubMed ID: 1688241
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  • 20. Influence of phenylalanine-481 substitutions on the catalytic activity of cytochrome P450 2D6.
    Hayhurst GP, Harlow J, Chowdry J, Gross E, Hilton E, Lennard MS, Tucker GT, Ellis SW.
    Biochem J; 2001 Apr 15; 355(Pt 2):373-9. PubMed ID: 11284724
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