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PUBMED FOR HANDHELDS

Journal Abstract Search


256 related items for PubMed ID: 8916913

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  • 4. The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant.
    Harrison DH, Bohren KM, Petsko GA, Ringe D, Gabbay KH.
    Biochemistry; 1997 Dec 23; 36(51):16134-40. PubMed ID: 9405046
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  • 5. Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites.
    El-Kabbani O, Old SE, Ginell SL, Carper DA.
    Mol Vis; 1999 Sep 03; 5():20. PubMed ID: 10493777
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  • 7. Kinetic and spectroscopic evidence for active site inhibition of human aldose reductase.
    Nakano T, Petrash JM.
    Biochemistry; 1996 Aug 27; 35(34):11196-202. PubMed ID: 8780524
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  • 8. Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.
    Kratzer R, Kavanagh KL, Wilson DK, Nidetzky B.
    Biochemistry; 2004 May 04; 43(17):4944-54. PubMed ID: 15109252
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  • 9. Structural features of the aldose reductase and aldehyde reductase inhibitor-binding sites.
    El-Kabbani O, Wilson DK, Petrash M, Quiocho FA.
    Mol Vis; 1998 Sep 29; 4():19. PubMed ID: 9756955
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  • 10. High-resolution crystal structure of aldose reductase complexed with the novel sulfonyl-pyridazinone inhibitor exhibiting an alternative active site anchoring group.
    Steuber H, Zentgraf M, Podjarny A, Heine A, Klebe G.
    J Mol Biol; 2006 Feb 10; 356(1):45-56. PubMed ID: 16337231
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  • 14. Electrostatic stabilization in a pre-organized polar active site: the catalytic role of Lys-80 in Candida tenuis xylose reductase (AKR2B5) probed by site-directed mutagenesis and functional complementation studies.
    Kratzer R, Nidetzky B.
    Biochem J; 2005 Jul 15; 389(Pt 2):507-15. PubMed ID: 15799715
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  • 16. Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases.
    Kavanagh KL, Klimacek M, Nidetzky B, Wilson DK.
    Biochem J; 2003 Jul 15; 373(Pt 2):319-26. PubMed ID: 12733986
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  • 17. Oxidized aldose reductase: in vivo factor not in vitro artifact.
    Grimshaw CE, Lai CJ.
    Arch Biochem Biophys; 1996 Mar 01; 327(1):89-97. PubMed ID: 8615700
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  • 19. Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity.
    El-Kabbani O, Carbone V, Darmanin C, Oka M, Mitschler A, Podjarny A, Schulze-Briese C, Chung RP.
    J Med Chem; 2005 Aug 25; 48(17):5536-42. PubMed ID: 16107153
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  • 20. Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features.
    Steuber H, Heine A, Podjarny A, Klebe G.
    J Mol Biol; 2008 Jun 20; 379(5):991-1016. PubMed ID: 18495158
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