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187 related items for PubMed ID: 8917684

  • 1. Physiologically based pharmacodynamic modeling of an interaction threshold between trichloroethylene and 1,1-dichloroethylene in Fischer 344 rats.
    el-Masri HA, Constan AA, Ramsdell HS, Yang RS.
    Toxicol Appl Pharmacol; 1996 Nov; 141(1):124-32. PubMed ID: 8917684
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  • 2. Chloroethylene mixtures: pharmacokinetic modeling and in vitro metabolism of vinyl chloride, trichloroethylene, and trans-1,2-dichloroethylene in rat.
    Barton HA, Creech JR, Godin CS, Randall GM, Seckel CS.
    Toxicol Appl Pharmacol; 1995 Feb; 130(2):237-47. PubMed ID: 7871537
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  • 3. Exploration of an interaction threshold for the joint toxicity of trichloroethylene and 1,1-dichloroethylene: utilization of a PBPK model.
    el-Masri HA, Tessari JD, Yang RS.
    Arch Toxicol; 1996 Feb; 70(9):527-39. PubMed ID: 8831903
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  • 4. Quantitative evaluation of the metabolic interactions between trichloroethylene and 1,1-dichloroethylene in vivo using gas uptake methods.
    Andersen ME, Gargas ML, Clewell HJ, Severyn KM.
    Toxicol Appl Pharmacol; 1987 Jun 30; 89(2):149-57. PubMed ID: 3603553
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  • 6. A gas-liquid system for enzyme kinetic studies of volatile organic chemicals. Determination of enzyme kinetic constants and partition coefficients of trichloroethylene.
    Hwang IY, Reardon KF, Tessari JD, Yang RS.
    Drug Metab Dispos; 1996 Apr 30; 24(4):377-82. PubMed ID: 8801050
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  • 7. Development of an updated PBPK model for trichloroethylene and metabolites in mice, and its application to discern the role of oxidative metabolism in TCE-induced hepatomegaly.
    Evans MV, Chiu WA, Okino MS, Caldwell JC.
    Toxicol Appl Pharmacol; 2009 May 01; 236(3):329-40. PubMed ID: 19249323
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  • 8. Conjugation of glutathione with the reactive metabolites of 1, 1-dichloroethylene in murine lung and liver.
    Forkert PG.
    Microsc Res Tech; 1997 Feb 15; 36(4):234-42. PubMed ID: 9140924
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  • 9. 1,1-Dichloroethylene elicits dose-dependent alterations in covalent binding and glutathione in murine liver.
    Gek Forkert P, Moussa M.
    Drug Metab Dispos; 1991 Feb 15; 19(3):580-6. PubMed ID: 1717215
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  • 13. A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
    Abbas R, Fisher JW.
    Toxicol Appl Pharmacol; 1997 Nov 15; 147(1):15-30. PubMed ID: 9356303
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  • 15. Assessing interaction thresholds for trichloroethylene in combination with tetrachloroethylene and 1,1,1-trichloroethane using gas uptake studies and PBPK modeling.
    Dobrev ID, Andersen ME, Yang RS.
    Arch Toxicol; 2001 May 15; 75(3):134-44. PubMed ID: 11409535
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  • 17. Physiologically based pharmacokinetic modeling of a ternary mixture of alkyl benzenes in rats and humans.
    Tardif R, Charest-Tardif G, Brodeur J, Krishnan K.
    Toxicol Appl Pharmacol; 1997 May 15; 144(1):120-34. PubMed ID: 9169076
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  • 18. A physiologically based pharmacokinetic (PB-PK) model for 1,2-dichlorobenzene linked to two possible parameters of toxicity.
    Hissink AM, Van Ommen B, Krüse J, Van Bladeren PJ.
    Toxicol Appl Pharmacol; 1997 Aug 15; 145(2):301-10. PubMed ID: 9266803
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  • 19. A comparison of physiologically based pharmacokinetic model predictions and experimental data for inhaled ethanol in male and female B6C3F1 mice, F344 rats, and humans.
    Pastino GM, Asgharian B, Roberts K, Medinsky MA, Bond JA.
    Toxicol Appl Pharmacol; 1997 Jul 15; 145(1):147-57. PubMed ID: 9221833
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  • 20. Theoretical study of the SNV reaction of trichloroethylene (TCE) and CH3S- as a model for glutathione conjugation of TCE.
    Shim JY, Boone PF, Richard AM.
    Chem Res Toxicol; 1999 Apr 15; 12(4):308-16. PubMed ID: 10207118
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