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Journal Abstract Search

171 related items for PubMed ID: 8924375

  • 1. New antifolates in clinical development.
    Takimoto CH, Allegra CJ.
    Oncology (Williston Park); 1995 Jul; 9(7):649-56, 659 DISC 660, 662, 665. PubMed ID: 8924375
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  • 2. Antifolates: the next generation.
    Fleming GF, Schilsky RL.
    Semin Oncol; 1992 Dec; 19(6):707-19. PubMed ID: 1462168
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  • 3. Antifolates in clinical development.
    Takimoto CH.
    Semin Oncol; 1997 Oct; 24(5 Suppl 18):S18-40-S18-51. PubMed ID: 9420020
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  • 9. Activity of antifolates against Pneumocystis carinii dihydrofolate reductase and identification of a potent new agent.
    Allegra CJ, Kovacs JA, Drake JC, Swan JC, Chabner BA, Masur H.
    J Exp Med; 1987 Mar 01; 165(3):926-31. PubMed ID: 2950200
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  • 12. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
    Rosowsky A, Galivan J, Beardsley GP, Bader H, O'Connor BM, Russello O, Moroson BA, DeYarman MT, Kerwar SS, Freisheim JH.
    Cancer Res; 1992 Apr 15; 52(8):2148-55. PubMed ID: 1313737
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  • 13. Characterization of trimetrexate transport in human lymphoblastoid cells and development of impaired influx as a mechanism of resistance to lipophilic antifolates.
    Fry DW, Besserer JA.
    Cancer Res; 1988 Dec 15; 48(24 Pt 1):6986-91. PubMed ID: 2973370
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  • 14. Mutant Gly482 and Thr482 ABCG2 mediate high-level resistance to lipophilic antifolates.
    Bram E, Ifergan I, Shafran A, Berman B, Jansen G, Assaraf YG.
    Cancer Chemother Pharmacol; 2006 Dec 15; 58(6):826-34. PubMed ID: 16612649
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  • 15. Cellular and molecular mechanisms of resistance to antifolate drugs: new analogues and approaches to overcome the resistance.
    Takemura Y, Kobayashi H, Miyachi H.
    Int J Hematol; 1997 Dec 15; 66(4):459-77. PubMed ID: 9479873
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  • 16. Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets.
    Assaraf YG, Ifergan I, Kadry WN, Pinter RY.
    J Theor Biol; 2006 Jun 21; 240(4):637-47. PubMed ID: 16352313
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  • 17. A phenotype conferring selective resistance to lipophilic antifolates in Chinese hamster ovary cells.
    Sharma RC, Assaraf YG, Schimke RT.
    Cancer Res; 1991 Jun 01; 51(11):2949-59. PubMed ID: 1674447
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  • 18. Tomudex (ZD1694): from concept to care, a programme in rational drug discovery.
    Jackman AL, Boyle FT, Harrap KR.
    Invest New Drugs; 1996 Jun 01; 14(3):305-16. PubMed ID: 8958186
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  • 19. Synthesis and antiparasitic and antitumor activity of 2, 4-diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritrexim.
    Rosowsky A, Papoulis AT, Forsch RA, Queener SF.
    J Med Chem; 1999 Mar 25; 42(6):1007-17. PubMed ID: 10090784
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  • 20. 6-Substituted 2,4-diaminopyrido[3,2-d]pyrimidine analogues of piritrexim as inhibitors of dihydrofolate reductase from rat liver, Pneumocystis carinii, and Toxoplasma gondii and as antitumor agents.
    Gangjee A, Zhu Y, Queener SF.
    J Med Chem; 1998 Nov 05; 41(23):4533-41. PubMed ID: 9804692
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