These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

583 related items for PubMed ID: 8930177

  • 1. Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.
    Masubuchi Y, Igarashi S, Suzuki T, Horie T, Narimatsu S.
    J Pharmacol Exp Ther; 1996 Nov; 279(2):724-31. PubMed ID: 8930177
    [Abstract] [Full Text] [Related]

  • 2. Inhibition and induction of cytochrome P450 isozymes after repetitive administration of imipramine in rats.
    Masubuchi Y, Takahashii C, Fujio N, Horie T, Suzuki T, Imaoka S, Funae Y, Narimatsu S.
    Drug Metab Dispos; 1995 Sep; 23(9):999-1003. PubMed ID: 8565792
    [Abstract] [Full Text] [Related]

  • 3. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
    Hissink AM, Oudshoorn MJ, Van Ommen B, Haenen GR, Van Bladeren PJ.
    Chem Res Toxicol; 1996 Dec; 9(8):1249-56. PubMed ID: 8951226
    [Abstract] [Full Text] [Related]

  • 4. Regioselective contribution of the cytochrome P-450 2D subfamily to propranolol metabolism in rat liver microsomes.
    Masubuchi Y, Kagimoto N, Narimatsu S, Fujita S, Suzuki T.
    Drug Metab Dispos; 1993 Dec; 21(6):1012-6. PubMed ID: 7905378
    [Abstract] [Full Text] [Related]

  • 5. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Woodcroft KJ, Webb CD, Yao M, Weedon AC, Bend JR.
    Chem Res Toxicol; 1997 May; 10(5):589-99. PubMed ID: 9168258
    [Abstract] [Full Text] [Related]

  • 6. Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein.
    Masubuchi Y, Araki J, Narimatsu S, Suzuki T.
    Biochem Pharmacol; 1992 Jun 23; 43(12):2551-7. PubMed ID: 1632813
    [Abstract] [Full Text] [Related]

  • 7. Covalent binding of a reactive metabolite derived from propranolol and its active metabolite 4-hydroxypropranolol to hepatic microsomal proteins of the rat.
    Narimatsu S, Arai T, Watanabe T, Masubuchi Y, Horie T, Suzuki T, Ishikawa T, Tsutsui M, Kumagai Y, Cho AK.
    Chem Res Toxicol; 1997 Mar 23; 10(3):289-95. PubMed ID: 9084908
    [Abstract] [Full Text] [Related]

  • 8. Microsomal metabolism of delavirdine: evidence for mechanism-based inactivation of human cytochrome P450 3A.
    Voorman RL, Maio SM, Payne NA, Zhao Z, Koeplinger KA, Wang X.
    J Pharmacol Exp Ther; 1998 Oct 23; 287(1):381-8. PubMed ID: 9765359
    [Abstract] [Full Text] [Related]

  • 9. Suicide inactivation of cytochrome P-450 by methoxsalen. Evidence for the covalent binding of a reactive intermediate to the protein moiety.
    Labbe G, Descatoire V, Beaune P, Letteron P, Larrey D, Pessayre D.
    J Pharmacol Exp Ther; 1989 Sep 23; 250(3):1034-42. PubMed ID: 2506333
    [Abstract] [Full Text] [Related]

  • 10. Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats.
    Suzuki T, Narimatsu S, Fujita S, Masubuchi Y, Umeda S, Imaoka S, Funae Y.
    Drug Metab Dispos; 1992 Sep 23; 20(3):367-73. PubMed ID: 1355709
    [Abstract] [Full Text] [Related]

  • 11. Role of the CYP2D subfamily in metabolism-dependent covalent binding of propranolol to liver microsomal protein in rats.
    Masubuchi Y, Narimatsu S, Hosokawa S, Suzuki T.
    Biochem Pharmacol; 1994 Nov 16; 48(10):1891-8. PubMed ID: 7986200
    [Abstract] [Full Text] [Related]

  • 12. Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol.
    Narimatsu S, Arai T, Masubuchi Y, Horie T, Hosokawa M, Ueno K, Kataoka H, Yamamoto S, Ishikawa T, Cho AK.
    Biol Pharm Bull; 2001 Sep 16; 24(9):988-94. PubMed ID: 11558582
    [Abstract] [Full Text] [Related]

  • 13. Characterization of the NADPH-dependent covalent binding of [14C]halothane to human liver microsomes: a role for cytochrome P4502E1 at low substrate concentrations.
    Madan A, Parkinson A.
    Drug Metab Dispos; 1996 Dec 16; 24(12):1307-13. PubMed ID: 8971135
    [Abstract] [Full Text] [Related]

  • 14. Purification and characterization of a dog cytochrome P450 isozyme belonging to the CYP2D subfamily and development of its antipeptide antibody.
    Nakamura A, Yamamoto Y, Tasaki T, Sugimoto C, Masuda M, Kazusaka A, Fujita S.
    Drug Metab Dispos; 1995 Nov 16; 23(11):1268-73. PubMed ID: 8591729
    [Abstract] [Full Text] [Related]

  • 15. Different effects of desipramine on bufuralol 1''-hydroxylation by rat and human CYP2D enzymes.
    Isobe T, Hichiya H, Hanioka N, Yamamoto S, Shinoda S, Funae Y, Satoh T, Yamano S, Narimatsu S.
    Biol Pharm Bull; 2005 Apr 16; 28(4):634-40. PubMed ID: 15802801
    [Abstract] [Full Text] [Related]

  • 16. Effects of antidepressant drugs on the activity of cytochrome P-450 measured by caffeine oxidation in rat liver microsomes.
    Danie WA, Syrek M, Ryłko Z, Wójcikowski J.
    Pol J Pharmacol; 2001 Apr 16; 53(4):351-7. PubMed ID: 11990081
    [Abstract] [Full Text] [Related]

  • 17. Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.
    Munns AJ, De Voss JJ, Hooper WD, Dickinson RG, Gillam EM.
    Chem Res Toxicol; 1997 Sep 16; 10(9):1049-58. PubMed ID: 9305589
    [Abstract] [Full Text] [Related]

  • 18.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 19. The 1'-hydroxylation of Rac-bufuralol by rat brain microsomes.
    Coleman T, Spellman EF, Rostami-Hodjegan A, Lennard MS, Tucker GT.
    Drug Metab Dispos; 2000 Sep 16; 28(9):1094-9. PubMed ID: 10950855
    [Abstract] [Full Text] [Related]

  • 20.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 30.