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Journal Abstract Search


162 related items for PubMed ID: 8937438

  • 1. Biological properties of fluoroglutamate-containing analogs of folates and methotrexate with altered capacities to form poly (gamma-glutamate) metabolites.
    McGuire JJ, Hart BP, Haile WH, Magee KJ, Rhee M, Bolanowska WE, Russell C, Galivan J, Paul B, Coward JK.
    Biochem Pharmacol; 1996 Oct 25; 52(8):1295-303. PubMed ID: 8937438
    [Abstract] [Full Text] [Related]

  • 2. gamma-Fluoromethotrexate: synthesis and biological activity of a potent inhibitor of dihydrofolate reductase with greatly diminished ability to form poly-gamma-glutamates.
    Galivan J, Inglese J, McGuire JJ, Nimec Z, Coward JK.
    Proc Natl Acad Sci U S A; 1985 May 25; 82(9):2598-602. PubMed ID: 2581252
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  • 3. Biochemical and growth inhibitory effects of the erythro and threo isomers of gamma-fluoromethotrexate, a methotrexate analogue defective in polyglutamylation.
    McGuire JJ, Graber M, Licato N, Vincenz C, Coward JK, Nimec Z, Galivan J.
    Cancer Res; 1989 Aug 15; 49(16):4517-25. PubMed ID: 2472880
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  • 4. Synthesis and biological activity of folic acid and methotrexate analogues containing L-threo-(2S,4S)-4-fluoroglutamic acid and DL-3,3-difluoroglutamic acid.
    Hart BP, Haile WH, Licato NJ, Bolanowska WE, McGuire JJ, Coward JK.
    J Med Chem; 1996 Jan 05; 39(1):56-65. PubMed ID: 8568827
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  • 5. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.
    Jansen G, Mauritz RM, Assaraf YG, Sprecher H, Drori S, Kathmann I, Westerhof GR, Priest DG, Bunni M, Pinedo HM, Schornagel JH, Peters GJ.
    Adv Enzyme Regul; 1997 Jan 05; 37():59-76. PubMed ID: 9381986
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  • 7. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
    Mauritz R, Peters GJ, Priest DG, Assaraf YG, Drori S, Kathmann I, Noordhuis P, Bunni MA, Rosowsky A, Schornagel JH, Pinedo HM, Jansen G.
    Biochem Pharmacol; 2002 Jan 15; 63(2):105-15. PubMed ID: 11841783
    [Abstract] [Full Text] [Related]

  • 8. DL-beta,beta-difluoroglutamic acid mediates position-dependent enhancement or termination of pteroylpoly(gamma-glutamate) synthesis catalyzed by folylpolyglutamate synthetase.
    McGuire JJ, Hart BP, Haile WH, Rhee MS, Galivan J, Coward JK.
    Arch Biochem Biophys; 1995 Aug 20; 321(2):319-28. PubMed ID: 7646057
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  • 10. Folate analogues. 33. Synthesis of folate and antifolate poly-gamma-glutamates by [(9-fluorenylmethoxy)oxy]carbonyl chemistry and biological evaluation of certain methotrexate polyglutamate polylysine conjugates as inhibitors of the growth of H35 hepatoma cells.
    Abraham A, Nair MG, Kisliuk RL, Gaumont Y, Galivan J.
    J Med Chem; 1990 Feb 20; 33(2):711-7. PubMed ID: 1688946
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  • 11. Folate analog nonsubstrates and inhibitors of folylpolyglutamate synthetase as potential cancer chemotherapy drugs.
    McGuire JJ, Piper JR, Coward JK, Galivan J.
    NCI Monogr; 1987 Feb 20; (5):139-44. PubMed ID: 2448652
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  • 12. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
    Rosowsky A, Galivan J, Beardsley GP, Bader H, O'Connor BM, Russello O, Moroson BA, DeYarman MT, Kerwar SS, Freisheim JH.
    Cancer Res; 1992 Apr 15; 52(8):2148-55. PubMed ID: 1313737
    [Abstract] [Full Text] [Related]

  • 13. Rescue effect of exogenous reduced folates on methotrexate polyglutamylation and dihydrofolate reductase activity in L1210 cells.
    Balińska M.
    Acta Biochim Pol; 1988 Apr 15; 35(3):199-205. PubMed ID: 2469275
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  • 14. Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance.
    Jansen G, Westerhof GR, Kathmann I, Rademaker BC, Rijksen G, Schornagel JH.
    Cancer Res; 1989 May 01; 49(9):2455-9. PubMed ID: 2706633
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  • 15. Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
    Miyachi H, Takemura Y, Kobayashi H, Ando Y.
    Jpn J Cancer Res; 1997 Sep 01; 88(9):900-6. PubMed ID: 9369939
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  • 17. Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors.
    Jansen G, Schornagel JH, Westerhof GR, Rijksen G, Newell DR, Jackman AL.
    Cancer Res; 1990 Dec 01; 50(23):7544-8. PubMed ID: 2253202
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  • 18. Further studies on the pharmacologic effects of the 7-hydroxy catabolite of methotrexate in the L1210 murine leukemia cell.
    Seither RL, Rape TJ, Goldman ID.
    Biochem Pharmacol; 1989 Mar 01; 38(5):815-22. PubMed ID: 2467676
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  • 19. Thymidylate synthase as a target for growth inhibition in methotrexate-sensitive and -resistant human head and neck cancer and leukemia cell lines.
    McGuire JJ, Magee KJ, Russell CA, Canestrari JM.
    Oncol Res; 1997 Mar 01; 9(3):139-47. PubMed ID: 9220499
    [Abstract] [Full Text] [Related]

  • 20. Interaction of methotrexate polyglutamates and dihydrofolate during leucovorin rescue in a human breast cancer cell line (MCF-7).
    Allegra CJ, Boarman D.
    Cancer Res; 1990 Jun 15; 50(12):3574-8. PubMed ID: 1692762
    [Abstract] [Full Text] [Related]


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