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Journal Abstract Search

188 related items for PubMed ID: 8939861

  • 1. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation.
    Wolozin B, Iwasaki K, Vito P, Ganjei JK, Lacanà E, Sunderland T, Zhao B, Kusiak JW, Wasco W, D'Adamio L.
    Science; 1996 Dec 06; 274(5293):1710-3. PubMed ID: 8939861
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  • 2. Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.
    Guo Q, Sopher BL, Furukawa K, Pham DG, Robinson N, Martin GM, Mattson MP.
    J Neurosci; 1997 Jun 01; 17(11):4212-22. PubMed ID: 9151738
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  • 5. Cytotoxic mechanisms by M239V presenilin 2, a little-analyzed Alzheimer's disease-causative mutant.
    Abe Y, Hashimoto Y, Tomita Y, Terashita K, Aiso S, Tajima H, Niikura T, Matsuoka M, Nishimoto I.
    J Neurosci Res; 2004 Aug 15; 77(4):583-95. PubMed ID: 15264228
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  • 6. G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP.
    Giambarella U, Yamatsuji T, Okamoto T, Matsui T, Ikezu T, Murayama Y, Levine MA, Katz A, Gautam N, Nishimoto I.
    EMBO J; 1997 Aug 15; 16(16):4897-907. PubMed ID: 9305632
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  • 7. Sensitization of differentiated PC12 cells to apoptosis by presenilin-2 is mediated by p38.
    Sun J, Li M, Han J, Gu J.
    Biochem Biophys Res Commun; 2001 Sep 21; 287(2):536-41. PubMed ID: 11554762
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  • 8. The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue.
    Tomita T, Maruyama K, Saido TC, Kume H, Shinozaki K, Tokuhiro S, Capell A, Walter J, Grünberg J, Haass C, Iwatsubo T, Obata K.
    Proc Natl Acad Sci U S A; 1997 Mar 04; 94(5):2025-30. PubMed ID: 9050898
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  • 17. Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease.
    Guo Q, Fu W, Xie J, Luo H, Sells SF, Geddes JW, Bondada V, Rangnekar VM, Mattson MP.
    Nat Med; 1998 Aug 04; 4(8):957-62. PubMed ID: 9701251
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  • 18. [The AAP and PS1/2 mutations linked to early onset familial Alzheimer's disease increase the extracellular concentration and A beta 1-42 (43)].
    Younkin SG.
    Rinsho Shinkeigaku; 1997 Dec 04; 37(12):1099. PubMed ID: 9577655
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  • 19. [Alzheimer's disease due to presenilin mutations].
    Tabira T.
    Nihon Rinsho; 2004 Jan 04; 62 Suppl():90-4. PubMed ID: 15011327
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  • 20. Dissecting how presinilins function--and malfunction.
    Marx J.
    Science; 1996 Dec 13; 274(5294):1838-40. PubMed ID: 8984642
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