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121 related items for PubMed ID: 8955373

  • 1. Overexpression of G(s)alpha in NG108-15, neuroblastomaXglioma cells: effects on receptor regulation of the stimulatory adenylyl cyclase cascade.
    Mullaney I, Carr IC, Milligan G.
    FEBS Lett; 1996 Nov 18; 397(2-3):325-30. PubMed ID: 8955373
    [Abstract] [Full Text] [Related]

  • 2. A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization.
    Mundell SJ, Benovic JL, Kelly E.
    Mol Pharmacol; 1997 Jun 18; 51(6):991-8. PubMed ID: 9187265
    [Abstract] [Full Text] [Related]

  • 3. Concurrent down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs) during prolonged exposure of neuroblastoma x glioma cells to prostanoid agonists. Quantification and functional implications.
    Adie EJ, Mullaney I, McKenzie FR, Milligan G.
    Biochem J; 1992 Jul 15; 285 ( Pt 2)(Pt 2):529-36. PubMed ID: 1379045
    [Abstract] [Full Text] [Related]

  • 4. Gs alpha-dependent and -independent desensitisation of prostanoid IP receptor-activated adenylyl cyclase in NG108-15 cells.
    Williams RJ, Kelly E.
    Eur J Pharmacol; 1994 Jul 15; 268(2):177-86. PubMed ID: 7525317
    [Abstract] [Full Text] [Related]

  • 5. Quantitative stoichiometry of the proteins of the stimulatory arm of the adenylyl cyclase cascade in neuroblastoma x glioma hybrid, NG108-15 cells.
    Kim GD, Adie EJ, Milligan G.
    Eur J Biochem; 1994 Jan 15; 219(1-2):135-43. PubMed ID: 8306980
    [Abstract] [Full Text] [Related]

  • 6. Enhanced expression of G protein-coupled receptor kinase 2 selectively increases the sensitivity of A2A adenosine receptors to agonist-induced desensitization.
    Mundell SJ, Luty JS, Willets J, Benovic JL, Kelly E.
    Br J Pharmacol; 1998 Sep 15; 125(2):347-56. PubMed ID: 9786508
    [Abstract] [Full Text] [Related]

  • 7. Segregation of discrete GS alpha-mediated responses that accompany homologous or heterologous desensitization in two related somatic hybrids.
    Kelly E, Keen M, Nobbs P, MacDermot J.
    Br J Pharmacol; 1990 Feb 15; 99(2):309-16. PubMed ID: 1691675
    [Abstract] [Full Text] [Related]

  • 8. Agonist regulation of cellular Gs alpha-subunit levels in neuroblastoma x glioma hybrid NG108-15 cells transfected to express different levels of the human beta 2 adrenoceptor.
    Adie EJ, Milligan G.
    Biochem J; 1994 Jun 15; 300 ( Pt 3)(Pt 3):709-15. PubMed ID: 7516655
    [Abstract] [Full Text] [Related]

  • 9. Evidence for co-expression and desensitization of A2a and A2b adenosine receptors in NG108-15 cells.
    Mundell SJ, Kelly E.
    Biochem Pharmacol; 1998 Mar 01; 55(5):595-603. PubMed ID: 9515570
    [Abstract] [Full Text] [Related]

  • 10. Agonist regulation of adenylate cyclase activity in neuroblastoma x glioma hybrid NG108-15 cells transfected to co-express adenylate cyclase type II and the beta 2-adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediated stimulation of adenylate cyclase activity.
    MacEwan DJ, Kim GD, Milligan G.
    Biochem J; 1996 Sep 15; 318 ( Pt 3)(Pt 3):1033-9. PubMed ID: 8836153
    [Abstract] [Full Text] [Related]

  • 11. Detection and analysis of agonist-induced formation of the complex of the stimulatory guanine nucleotide-binding protein with adenylate cyclase in intact wild-type and beta 2-adrenoceptor-expressing NG108-15 cells.
    Kim GD, Carr IC, Milligan G.
    Biochem J; 1995 May 15; 308 ( Pt 1)(Pt 1):275-81. PubMed ID: 7538756
    [Abstract] [Full Text] [Related]

  • 12. G protein-coupled receptor kinase 6 (GRK6) selectively regulates endogenous secretin receptor responsiveness in NG108-15 cells.
    Ghadessy RS, Willets JM, Kelly E.
    Br J Pharmacol; 2003 Feb 15; 138(4):660-70. PubMed ID: 12598420
    [Abstract] [Full Text] [Related]

  • 13. Regulation of cellular Gs alpha levels and basal adenylyl cyclase activity by expression of the beta 2-adrenoceptor in neuroblastoma cell lines.
    Milligan G, Kim GD, Mullaney I, Adie EJ.
    Mol Cell Biochem; 1995 Feb 15; 149-150():213-6. PubMed ID: 8569731
    [Abstract] [Full Text] [Related]

  • 14. Evidence for the shuttle model for Gs alpha activation of adenylyl cyclase.
    Krumins AM, Lapeyre JN, Clark RB, Barber R.
    Biochem Pharmacol; 1997 Jul 01; 54(1):43-59. PubMed ID: 9296350
    [Abstract] [Full Text] [Related]

  • 15. NaF and guanine nucleotides modulate adenylate cyclase activity in NG108-15 cells by interacting with both Gs and Gi.
    Kelly E, Keen M, Nobbs P, MacDermot J.
    Br J Pharmacol; 1990 Jun 01; 100(2):223-30. PubMed ID: 1696150
    [Abstract] [Full Text] [Related]

  • 16. The effect of inhibitors of receptor internalization on the desensitization and resensitization of three Gs-coupled receptor responses.
    Mundell SJ, Kelly E.
    Br J Pharmacol; 1998 Dec 01; 125(7):1594-600. PubMed ID: 9884089
    [Abstract] [Full Text] [Related]

  • 17. Cyclopentyladenosine-induced homologous down-regulation of A1 adenosine receptors (A1AR) in intact neurons is accompanied by receptor sequestration but not a reduction in A1AR mRNA expression or G protein alpha-subunit content.
    Hettinger BD, Leid M, Murray TF.
    J Neurochem; 1998 Jul 01; 71(1):221-30. PubMed ID: 9648869
    [Abstract] [Full Text] [Related]

  • 18. Regulation of basal adenylate cyclase activity in neuroblastoma x glioma hybrid, NG108-15, cells transfected to express the human beta 2 adrenoceptor: evidence for empty receptor stimulation of the adenylate cyclase cascade.
    Adie EJ, Milligan G.
    Biochem J; 1994 Nov 01; 303 ( Pt 3)(Pt 3):803-8. PubMed ID: 7980449
    [Abstract] [Full Text] [Related]

  • 19. Equivalent regulation of wild type and an epitope-tagged variant of Gs alpha by the IP prostanoid receptor following expression in neuroblastoma x glioma hybrid, NG108-15, cells.
    Mullaney I, Milligan G.
    FEBS Lett; 1994 Oct 24; 353(3):231-4. PubMed ID: 7525345
    [Abstract] [Full Text] [Related]

  • 20. A galpha(s) carboxyl-terminal peptide prevents G(s) activation by the A(2A) adenosine receptor.
    Mazzoni MR, Taddei S, Giusti L, Rovero P, Galoppini C, D'Ursi A, Albrizio S, Triolo A, Novellino E, Greco G, Lucacchini A, Hamm HE.
    Mol Pharmacol; 2000 Jul 24; 58(1):226-36. PubMed ID: 10860945
    [Abstract] [Full Text] [Related]


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