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Journal Abstract Search


104 related items for PubMed ID: 8962138

  • 1. Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: targeting with a single chain antibody variable domain isolated by phage display.
    Lorimer IA, Keppler-Hafkemeyer A, Beers RA, Pegram CN, Bigner DD, Pastan I.
    Proc Natl Acad Sci U S A; 1996 Dec 10; 93(25):14815-20. PubMed ID: 8962138
    [Abstract] [Full Text] [Related]

  • 2. Isolation of a high-affinity stable single-chain Fv specific for mesothelin from DNA-immunized mice by phage display and construction of a recombinant immunotoxin with anti-tumor activity.
    Chowdhury PS, Viner JL, Beers R, Pastan I.
    Proc Natl Acad Sci U S A; 1998 Jan 20; 95(2):669-74. PubMed ID: 9435250
    [Abstract] [Full Text] [Related]

  • 3. Regional treatment of epidermal growth factor receptor vIII-expressing neoplastic meningitis with a single-chain immunotoxin, MR-1.
    Archer GE, Sampson JH, Lorimer IA, McLendon RE, Kuan CT, Friedman AH, Friedman HS, Pastan IH, Bigner DD.
    Clin Cancer Res; 1999 Sep 20; 5(9):2646-52. PubMed ID: 10499644
    [Abstract] [Full Text] [Related]

  • 4. Construction of an immunotoxin, D2C7-(scdsFv)-PE38KDEL, targeting EGFRwt and EGFRvIII for brain tumor therapy.
    Chandramohan V, Bao X, Keir ST, Pegram CN, Szafranski SE, Piao H, Wikstrand CJ, McLendon RE, Kuan CT, Pastan IH, Bigner DD.
    Clin Cancer Res; 2013 Sep 01; 19(17):4717-27. PubMed ID: 23857604
    [Abstract] [Full Text] [Related]

  • 5. Increased binding affinity enhances targeting of glioma xenografts by EGFRvIII-specific scFv.
    Kuan CT, Wikstrand CJ, Archer G, Beers R, Pastan I, Zalutsky MR, Bigner DD.
    Int J Cancer; 2000 Dec 15; 88(6):962-9. PubMed ID: 11093822
    [Abstract] [Full Text] [Related]

  • 6. Targeting IL-13Ralpha2-positive cancer with a novel recombinant immunotoxin composed of a single-chain antibody and mutated Pseudomonas exotoxin.
    Kioi M, Seetharam S, Puri RK.
    Mol Cancer Ther; 2008 Jun 15; 7(6):1579-87. PubMed ID: 18566228
    [Abstract] [Full Text] [Related]

  • 7. Improved cytotoxic activity toward cell lines and fresh leukemia cells of a mutant anti-CD22 immunotoxin obtained by antibody phage display.
    Salvatore G, Beers R, Margulies I, Kreitman RJ, Pastan I.
    Clin Cancer Res; 2002 Apr 15; 8(4):995-1002. PubMed ID: 11948105
    [Abstract] [Full Text] [Related]

  • 8. A bivalent recombinant immunotoxin with high potency against tumors with EGFR and EGFRvIII expression.
    Meng J, Liu Y, Gao S, Lin S, Gu X, Pomper MG, Wang PC, Shan L.
    Cancer Biol Ther; 2015 Apr 15; 16(12):1764-74. PubMed ID: 26467217
    [Abstract] [Full Text] [Related]

  • 9. Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors.
    Lorimer IA, Wikstrand CJ, Batra SK, Bigner DD, Pastan I.
    Clin Cancer Res; 1995 Aug 15; 1(8):859-64. PubMed ID: 9816055
    [Abstract] [Full Text] [Related]

  • 10. Antigen binding and cytotoxic properties of a recombinant immunotoxin incorporating the lytic peptide, melittin.
    Dunn RD, Weston KM, Longhurst TJ, Lilley GG, Rivett DE, Hudson PJ, Raison RL.
    Immunotechnology; 1996 Sep 15; 2(3):229-40. PubMed ID: 9373315
    [Abstract] [Full Text] [Related]

  • 11. An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA') is a potent immunotoxin against a Hodgkin-derived cell line.
    Klimka A, Barth S, Matthey B, Roovers RC, Lemke H, Hansen H, Arends JW, Diehl V, Hoogenboom HR, Engert A.
    Br J Cancer; 1999 Jun 15; 80(8):1214-22. PubMed ID: 10376974
    [Abstract] [Full Text] [Related]

  • 12. 125I-labeled anti-epidermal growth factor receptor-vIII single-chain Fv exhibits specific and high-level targeting of glioma xenografts.
    Kuan CT, Reist CJ, Foulon CF, Lorimer IA, Archer G, Pegram CN, Pastan I, Zalutsky MR, Bigner DD.
    Clin Cancer Res; 1999 Jun 15; 5(6):1539-49. PubMed ID: 10389943
    [Abstract] [Full Text] [Related]

  • 13. Immunotoxins with increased activity against epidermal growth factor receptor vIII-expressing cells produced by antibody phage display.
    Beers R, Chowdhury P, Bigner D, Pastan I.
    Clin Cancer Res; 2000 Jul 15; 6(7):2835-43. PubMed ID: 10914732
    [Abstract] [Full Text] [Related]

  • 14. Isolation and characterization of a novel human scFv inhibiting EGFR vIII expressing cancers.
    Rahbarnia L, Farajnia S, Babaei H, Majidi J, Dariushnejad H, Hosseini MK.
    Immunol Lett; 2016 Dec 15; 180():31-38. PubMed ID: 27984065
    [Abstract] [Full Text] [Related]

  • 15. Expression of an oncogenic mutant EGF receptor markedly increases the sensitivity of cells to an EGF-receptor-specific antibody-toxin.
    Schmidt M, Reiser P, Hills D, Gullick WJ, Wels W.
    Int J Cancer; 1998 Mar 16; 75(6):878-84. PubMed ID: 9506533
    [Abstract] [Full Text] [Related]

  • 16. Affinity-matured anti-glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas.
    Kuan CT, Wakiya K, Keir ST, Li J, Herndon JE, Pastan I, Bigner DD.
    Int J Cancer; 2011 Jul 01; 129(1):111-21. PubMed ID: 20824708
    [Abstract] [Full Text] [Related]

  • 17. Radiolabeled novel mAb 4G1 for immunoSPECT imaging of EGFRvIII expression in preclinical glioblastoma xenografts.
    Liu X, Dong C, Shi J, Ma T, Jin Z, Jia B, Liu Z, Shen L, Wang F.
    Oncotarget; 2017 Jan 24; 8(4):6364-6375. PubMed ID: 28031526
    [Abstract] [Full Text] [Related]

  • 18. Development of a Novel Human Single Chain Antibody Against EGFRVIII Antigen by Phage Display Technology.
    Rahbarnia L, Farajnia S, Babaei H, Majidi J, Akbari B, Ahdi Khosroshahi S.
    Adv Pharm Bull; 2016 Dec 24; 6(4):563-571. PubMed ID: 28101463
    [Abstract] [Full Text] [Related]

  • 19. Improvement of a recombinant anti-monkey anti-CD3 diphtheria toxin based immunotoxin by yeast display affinity maturation of the scFv.
    Wang Z, Kim GB, Woo JH, Liu YY, Mathias A, Stavrou S, Neville DM.
    Bioconjug Chem; 2007 Dec 24; 18(3):947-55. PubMed ID: 17352456
    [Abstract] [Full Text] [Related]

  • 20. Affinity-matured recombinant immunotoxin targeting gangliosides 3'-isoLM1 and 3',6'-isoLD1 on malignant gliomas.
    Piao H, Kuan CT, Chandramohan V, Keir ST, Pegram CN, Bao X, Månsson JE, Pastan IH, Bigner DD.
    MAbs; 2013 Dec 24; 5(5):748-62. PubMed ID: 23924792
    [Abstract] [Full Text] [Related]


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